Quisqualic acid - ≥99%, high purity , CAS No.52809-07-1, Inhibitor of Cystine/glutamate transporter;Agonist of mGlu 1 receptor;Agonist of mGlu 5 receptor

Item Number
Q276562
Grouped product items
SKUSizeAvailabilityPrice Qty
Q276562-20mM-ml
20mM/ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$100.90

Group I mGlu agonist. AMPA agonist. 1 ml water soluble pack.

Basic Description

SynonymsNCGC00024489-07 | NCGC00261724-01 | HMS2233G05 | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID | MS-23020 | HMS3411A13 | L-quisqualic-acid | [3H]quisqualate | 1mm7 | (L)-(+)-?-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid | 8O
Specifications & PurityMoligand™, ≥99%
Biochemical and Physiological MechanismsPotent group I mGlu agonist and AMPA receptor agonist. Soluble in 1 ml water to give specified mM/ml concentration. Find out more.
Storage TempStore at 2-8°C,Desiccated
Shipped InWet ice
GradeMoligand™
Action TypeAGONIST, INHIBITOR
Mechanism of actionInhibitor of Cystine/glutamate transporter;Agonist of mGlu 1 receptor;Agonist of mGlu 5 receptor
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months.

Associated Targets(Human)

CYP3A4 Tclin Cytochrome P450 3A4 (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
SLC7A11 Tchem Cystine/glutamate transporter (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRM1 Tchem Metabotropic glutamate receptor 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
GRM5 Tchem Metabotropic glutamate receptor 5 (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid
INCHI InChI=1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1
InChi Key ASNFTDCKZKHJSW-REOHCLBHSA-N
Canonical SMILES C(C(C(=O)O)N)N1C(=O)NC(=O)O1
Isomeric SMILES C([C@@H](C(=O)O)N)N1C(=O)NC(=O)O1
WGK Germany 3
Alternate CAS 52809-07-1
PubChem CID 40539
MeSH Entry Terms Quisqualate;Quisqualic Acid
Molecular Weight 189.13
Beilstein 1078734

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Chemical and Physical Properties

SolubilitySoluble in 1ml of water to give specified mM/ml concentration

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

H312:Harmful in contact with skin

H332:Harmful if inhaled

H302+H312+H332:Harmful if swallowed, in contact with skin or if inhaled

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P271:Use only outdoors or in a well-ventilated area.

P270:Do not eat, drink or smoke when using this product.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P362+P364:Take off contaminated clothing and wash it before reuse.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

P317:Get emergency medical help.

WGK Germany 3

Related Documents

Solution Calculators