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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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Q276562-20mM-ml | 20mM/ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $100.90 |
Group I mGlu agonist. AMPA agonist. 1 ml water soluble pack.
Synonyms | NCGC00024489-07 | NCGC00261724-01 | HMS2233G05 | (S)-2-AMINO-3-(3,5-DIOXO-[1,2,4]OXADIAZOLIDIN-2-YL)-PROPIONIC ACID | MS-23020 | HMS3411A13 | L-quisqualic-acid | [3H]quisqualate | 1mm7 | (L)-(+)-?-Amino-3,5-dioxo-1,2,4-oxadiazolidine-2-propanoic acid | 8O |
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Specifications & Purity | Moligand™, ≥99% |
Biochemical and Physiological Mechanisms | Potent group I mGlu agonist and AMPA receptor agonist. Soluble in 1 ml water to give specified mM/ml concentration. Find out more. |
Storage Temp | Store at 2-8°C,Desiccated |
Shipped In | Wet ice |
Grade | Moligand™ |
Action Type | AGONIST, INHIBITOR |
Mechanism of action | Inhibitor of Cystine/glutamate transporter;Agonist of mGlu 1 receptor;Agonist of mGlu 5 receptor |
Note | Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details. |
Product Description | Store at +4°C. Store under desiccating conditions. The product can be stored for up to 12 months. |
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IUPAC Name | (2S)-2-amino-3-(3,5-dioxo-1,2,4-oxadiazolidin-2-yl)propanoic acid |
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INCHI | InChI=1S/C5H7N3O5/c6-2(3(9)10)1-8-4(11)7-5(12)13-8/h2H,1,6H2,(H,9,10)(H,7,11,12)/t2-/m0/s1 |
InChi Key | ASNFTDCKZKHJSW-REOHCLBHSA-N |
Canonical SMILES | C(C(C(=O)O)N)N1C(=O)NC(=O)O1 |
Isomeric SMILES | C([C@@H](C(=O)O)N)N1C(=O)NC(=O)O1 |
WGK Germany | 3 |
Alternate CAS | 52809-07-1 |
PubChem CID | 40539 |
MeSH Entry Terms | Quisqualate;Quisqualic Acid |
Molecular Weight | 189.13 |
Beilstein | 1078734 |
PubChem CID | 40539 |
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DrugBank Ligand | DB02999 |
Wikipedia | Quisqualic_acid |
ChEMBL Ligand | CHEMBL279956 |
CAS Registry No. | 52809-07-1 |
RCSB PDB Ligand | QUS |
GPCRdb Ligand | quisqualate |
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Solubility | Soluble in 1ml of water to give specified mM/ml concentration |
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Pictogram(s) | GHS07 |
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Signal | Warning |
Hazard Statements | H302:Harmful if swallowed H312:Harmful in contact with skin H332:Harmful if inhaled H302+H312+H332:Harmful if swallowed, in contact with skin or if inhaled |
Precautionary Statements | P261:Avoid breathing dust/fume/gas/mist/vapors/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of water. P321:Specific treatment (see ... on this label). P501:Dispose of contents/container to ... P264:Wash hands [and …] thoroughly after handling. P271:Use only outdoors or in a well-ventilated area. P270:Do not eat, drink or smoke when using this product. P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing. P362+P364:Take off contaminated clothing and wash it before reuse. P330:Rinse mouth. P301+P317:IF SWALLOWED: Get medical help. P317:Get emergency medical help. |
WGK Germany | 3 |