My Cart
You have no items in your shopping cart.
SKU | Size | Availability | Price | Qty |
---|---|---|---|---|
R609244-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $570.90 | |
R609244-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,000.90 |
Specifications & Purity | Moligand™ |
---|---|
Grade | Moligand™ |
Action Type | INHIBITOR |
Mechanism of action | Inhibitor of sphingosine kinase 1;Inhibitor of sphingosine kinase 2 |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
---|
IUPAC Name | (R)-(1-(4-((3-(Benzyloxy)phenoxy)methyl)benzyl)pyrrolidin-2-yl)methanol |
---|---|
INCHI | InChI=1S/C26H29NO3/c28-18-24-8-5-15-27(24)17-21-11-13-23(14-12-21)20-30-26-10-4-9-25(16-26)29-19-22-6-2-1-3-7-22/h1-4,6-7,9-14,16,24,28H,5,8,15,17-20H2/t24-/m1/s1 |
InChi Key | SPXSEZMVRJLHQG-XMMPIXPASA-N |
Canonical SMILES | OC[C@H]1CCCN1Cc1ccc(cc1)COc1cccc(c1)OCc1ccccc1 |
Isomeric SMILES | C1C[C@@H](N(C1)CC2=CC=C(C=C2)COC3=CC=CC(=C3)OCC4=CC=CC=C4)CO |
PubChem CID | 154699447 |
1. Adams DR, Tawati S, Berretta G, Rivas PL, Baiget J, Jiang Z, Alsfouk A, Mackay SP, Pyne NJ, Pyne S. (2019) Topographical Mapping of Isoform-Selectivity Determinants for J-Channel-Binding Inhibitors of Sphingosine Kinases 1 and 2.. J Med Chem, 62 (7): (3658-3676). [PMID:30889352] [10.1021/op500134e] |