Highly potent, selective H 3 receptor agonist (K d = 50 nM). Induces H 4 -mediated eosinophil shape change (EC 50 = 66 nM). Inhibits H 3 -mediated histamine synthesis and release in the CNS. Active in vivo.
Storage Temp
Room temperature
Shipped In
Normal
Grade
Moligand™
Action Type
AGONIST
Mechanism of action
Agonist of H 3 receptor;Agonist of H 4 receptor
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
Store at Room Temperature. The product can be stored for up to 12 months.
1.Zhenyu Shen, Zhexin Zhu, Gangqiang Wang, Zhendong Wang, Wenxing Chen, Wangyang Lu. (2023) Solar-initiated continuous electron injection to promote Fe3+/Fe2+ catalytic cycle in tourmaline/g-C3N4 composite system for enhanced PMS activation. JOURNAL OF SOLID STATE CHEMISTRY, 319 (123806). [PMID:]
References
1.West Jr RE, Zweig A, Shih NY, Siegel MI, Egan RW, Clark MA. (1990) Identification of two H3-histamine receptor subtypes.. Mol Pharmacol, 38 (5):(610-3). [PMID:2172771]
2.Zhenyu Shen, Zhexin Zhu, Gangqiang Wang, Zhendong Wang, Wenxing Chen, Wangyang Lu. (2023) Solar-initiated continuous electron injection to promote Fe3+/Fe2+ catalytic cycle in tourmaline/g-C3N4 composite system for enhanced PMS activation. JOURNAL OF SOLID STATE CHEMISTRY, 319 (123806). [PMID:]
Solution Calculators
Molarity Calculator
Determine the necessary mass, volume, or concentration for preparing a solution.
Dilution Calculator
Determine the dilution needed to prepare a stock solution.
