(R)-(+)-Blebbistatin - ≥99%(HPLC), high purity , CAS No.1177356-70-5

  • ≥99%(HPLC)
Item Number
R287278
Grouped product items
SKUSizeAvailabilityPrice Qty
R287278-5mg
5mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$212.90
R287278-10mg
10mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$327.90
R287278-25mg
25mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$735.90
R287278-50mg
50mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,326.90
R287278-100mg
100mg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$2,157.90

Selective inhibitor of myosin II ATPase activity. Inactive enantiomer of(±)-blebbistatin

Basic Description

Synonyms(3aR)-3a-hydroxy-6-methyl-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one | Blebbistatin, (+)- | CHEBI:75387 | (R)-3A-hydroxy-6-methyl-1-phenyl-3,3a-dihydro-1H-pyrrolo[2,3-b]quinolin-4(2H)-one | Q27145266 | J-003661 | UNII-XWG1958E8I | NCGC00025281-01 |
Specifications & Purity≥99%(HPLC)
Biochemical and Physiological MechanismsInactive enantiomer of the selective inhibitor of myosin II (±)-blebbistatin.Active EnantiomerandRacematealso available. Cell permeable: no Primary Target Inactive enantiomer of (±)-Blebbistatin Product does not compete with ATP. Reversible: no
Storage TempProtected from light,Store at -20°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 (345557 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
USP1 Tchem Ubiquitin carboxyl-terminal hydrolase 1 (22556 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Luciferin 4-monooxygenase (66902 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mapt Microtubule-associated protein tau (6 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rorc Nuclear receptor ROR-gamma (89407 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (3aR)-3a-hydroxy-6-methyl-1-phenyl-2,3-dihydropyrrolo[2,3-b]quinolin-4-one
INCHI InChI=1S/C18H16N2O2/c1-12-7-8-15-14(11-12)16(21)18(22)9-10-20(17(18)19-15)13-5-3-2-4-6-13/h2-8,11,22H,9-10H2,1H3/t18-/m0/s1
InChi Key LZAXPYOBKSJSEX-SFHVURJKSA-N
Canonical SMILES CC1=CC2=C(C=C1)N=C3C(C2=O)(CCN3C4=CC=CC=C4)O
Isomeric SMILES CC1=CC2=C(C=C1)N=C3[C@@](C2=O)(CCN3C4=CC=CC=C4)O
PubChem CID 6604910
Molecular Weight 292.34

Certificates

Certificate of Analysis(COA)

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5 results found

Lot NumberCertificate TypeDateItem
C2308052Certificate of AnalysisNov 16, 2022 R287278
C2308053Certificate of AnalysisNov 16, 2022 R287278
C2308054Certificate of AnalysisNov 16, 2022 R287278
C2308055Certificate of AnalysisNov 16, 2022 R287278
C2308056Certificate of AnalysisNov 16, 2022 R287278

Chemical and Physical Properties

SolubilitySolvent:DMSO, Max Conc. mg/mL: 29.23, Max Conc. mM: 100
Sensitivitylight sensitive

Related Documents

Solution Calculators