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(R)-CPP - ≥95%, high purity , CAS No.126453-07-4

  • ≥95%
Item Number
C274937
Grouped product items
SKUSizeAvailabilityPrice Qty
C274937-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$149.90
C274937-5mg
5mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$599.90
C274937-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,119.90
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Potent NMDA antagonist

View related series
Antagonists iGluR

Basic Description

Synonyms(R)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid | (2R)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid
Specifications & Purity≥95%
Biochemical and Physiological MechanismsHighly potent, competitive NMDA antagonist; more active enantiomer of ( RS )-CPP . (K i values are 0.04 (NR1/NR2A), 0.3 (NR1/NR2B), 0.6 (NR1/NR2C) and 2.0 μM (NR1/NR2D)).
Storage TempStore at -20°C,Desiccated
Shipped InIce chest + Ice pads
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.

Associated Targets

CYP1A2 Tchem Cytochrome P450 1A2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2D6 Tclin Cytochrome P450 2D6 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2C19 Tchem Cytochrome P450 2C19 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP3A4 Tclin Cytochrome P450 3A4 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CYP2C9 Tchem Cytochrome P450 2C9 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

HSD17B10 Tchem 3-hydroxyacyl-CoA dehydrogenase type-2 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

ALOX15 Tchem Arachidonate 15-lipoxygenase 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

CHRM1 Tclin Muscarinic acetylcholine receptor M1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

THRB Tclin Thyroid hormone receptor beta 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRIA3 Tclin Glutamate receptor 3 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRIN3A Tclin Glutamate receptor ionotropic, NMDA 3A 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

GRIN1 Tclin Glutamate receptor ionotropic, NMDA 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Names and Identifiers

IUPAC Name (2R)-4-(3-phosphonopropyl)piperazine-2-carboxylic acid
INCHI InChI=1S/C8H17N2O5P/c11-8(12)7-6-10(4-2-9-7)3-1-5-16(13,14)15/h7,9H,1-6H2,(H,11,12)(H2,13,14,15)/t7-/m1/s1
InChi Key CUVGUPIVTLGRGI-SSDOTTSWSA-N
Canonical SMILES C1CN(CC(N1)C(=O)O)CCCP(=O)(O)O
Isomeric SMILES C1CN(C[C@@H](N1)C(=O)O)CCCP(=O)(O)O
PubChem CID 6603754
Molecular Weight 252.21

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in water to 100 mM

Related Documents

 SDS

 Specification Sheet

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