(R)-CPPene (SDZ EAA 494) - ≥98%, high purity , CAS No.117414-74-1

  • ≥98%
Item Number
C275335
Grouped product items
SKUSizeAvailabilityPrice Qty
C275335-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$393.90

Potent competitive NMDA antagonist

Basic Description

SynonymsMidafotel | D-Cpp-ene | 117414-74-1 | SDZ-EAA 494 | SDZ-EAA-494 | Midafotel [INN] | d-cppene | Sdz eaa 494 | D-4-[(2E)-3-PHOSPHONO-2-PROPENYL]-2-PIPERAZINECARBOXYLIC ACID | 7LYU6ZF84G | DTXSID1045740 | (R,E)-4-(3-Phosphonoallyl)piperazine-2-carboxylic acid | NCGC00092278-02 | (R)-
Specifications & Purity≥98%
Biochemical and Physiological MechanismsPotent competitive NMDA antagonist. Centrally active following systemic administration. Also available in simple stock solutions add 1 ml of water to get an exact, ready-to-use concentration.
Storage TempRoom temperature,Desiccated
Shipped InNormal
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Store at Room Temperature. Store under desiccating conditions. The product can be stored for up to 12 months.

Associated Targets(Human)

ALOX15 Tchem Arachidonate 15-lipoxygenase (7108 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
PMP22 Tbio Peripheral myelin protein 22 (699 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Mus musculus (284745 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Rattus norvegicus (775804 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Grin1 Glutamate NMDA receptor (6467 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (2R)-4-[(E)-3-phosphonoprop-2-enyl]piperazine-2-carboxylic acid
INCHI InChI=1S/C8H15N2O5P/c11-8(12)7-6-10(4-2-9-7)3-1-5-16(13,14)15/h1,5,7,9H,2-4,6H2,(H,11,12)(H2,13,14,15)/b5-1+/t7-/m1/s1
InChi Key VZXMZMJSGLFKQI-ABVWVHJUSA-N
Canonical SMILES C1CN(CC(N1)C(=O)O)CC=CP(=O)(O)O
Isomeric SMILES C1CN(C[C@@H](N1)C(=O)O)C/C=C/P(=O)(O)O
PubChem CID 6435801
Molecular Weight 250.19

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySoluble in water to 100 mM

Related Documents

References

1. Chokshi V et al..  (2019)  Input-Specific Metaplasticity in the Visual Cortex Requires Homer1a-Mediated mGluR5 Signaling..  Neuron,  104  (4): (736-748.e6).  [PMID:31563294]

Solution Calculators