(R)-DPN - ≥98%(HPLC), high purity , CAS No.524047-78-7

  • ≥98%(HPLC)
Item Number
R288752
Grouped product items
SKUSizeAvailabilityPrice Qty
R288752-10mg
10mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$278.90

Enantiomer ofDPN

Basic Description

Synonyms(R)-Dpn | 524047-78-7 | (R)-2,3-Bis(4-hydroxyphenyl)-propionitrile | (2R)-2,3-bis(4-hydroxyphenyl)propanenitrile | Di-p-hydroxyphenylpropionitrile, (R)- | BG5CYS8SFD | CHEMBL198159 | UNII-BG5CYS8SFD | Tocris-1494 | (R)-di-p-hydroxyphenylpropionitrile | BDBM50364076 | Benzenepr
Specifications & Purity≥98%(HPLC)
Biochemical and Physiological MechanismsEnantiomer ofDPN. Displays higher affinity for estrogen receptor (ER)βover ERα(Kivalues are 1.82 and 147 nM respectively).
Storage TempStore at -20°C
Shipped InIce chest + Ice pads

Associated Targets(Human)

ESR1 Tclin Estrogen receptor (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ESR2 Tclin Estrogen receptor beta (4 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
ESR1 Tclin Estrogen receptor alpha (17718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR2 Tclin Estrogen receptor beta (9272 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ALDH1A1 Tchem Aldehyde dehydrogenase 1A1 (77053 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP1A2 Tchem Cytochrome P450 1A2 (26471 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C19 Tchem Cytochrome P450 2C19 (29246 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MEN1 Tchem Menin/Histone-lysine N-methyltransferase MLL (48157 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

lef Anthrax lethal factor (7585 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ESR1 Estrogen receptor (4 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SARS-CoV-2 (38078 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Names and Identifiers

IUPAC Name (2R)-2,3-bis(4-hydroxyphenyl)propanenitrile
INCHI InChI=1S/C15H13NO2/c16-10-13(12-3-7-15(18)8-4-12)9-11-1-5-14(17)6-2-11/h1-8,13,17-18H,9H2/t13-/m0/s1
InChi Key GHZHWDWADLAOIQ-ZDUSSCGKSA-N
Canonical SMILES C1=CC(=CC=C1CC(C#N)C2=CC=C(C=C2)O)O
Isomeric SMILES C1=CC(=CC=C1C[C@@H](C#N)C2=CC=C(C=C2)O)O
PubChem CID 6604873
Molecular Weight 239.27

Certificates

Certificate of Analysis(COA)

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Chemical and Physical Properties

SolubilitySolvent:1eq. NaOH, Max Conc. mg/mL: 5.98, Max Conc. mM: 25; Solvent:DMSO, Max Conc. mg/mL: 23.93, Max Conc. mM: 100; Solvent:ethanol, Max Conc. mg/mL: 23.93, Max Conc. mM: 100

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Solution Calculators