(R)-Equol , CAS No.221054-79-1

Item Number

R347296

Grouped product items
SKU	Size	Availability	Price	Qty
R347296-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$17.90
R347296-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$70.90

a non-steroidal estrogen produced from the metabolism of daidzein

Basic Description

Synonyms	(R)-Equol\|221054-79-1\|(+)-Equol\|Isoequol\|(R)-3-(4-hydroxyphenyl)chroman-7-ol\|R-Equol\|Equol, (+)-\|(3R)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-ol\|2V8RAP1HXA\|2H-1-Benzopyran-7-ol, 3,4-dihydro-3-(4-hydroxyphenyl)-, (3R)-\|UNII-2V8RAP1HXA\|EQUOL (R)-FORM\|S
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	(R)-Equol is a non-steroidal estrogen produced from the metabolism of the isoflavonoid phytoestrogen daidzein by human intestinal microflora. It is a chiral molecule that exists in two enantiomeric forms. In contrast to the estrogen receptor selectivity of (S)-equol , (R)-equol is a weaker ER agonist that binds to ERα and ERβ with K\|i\|values of 27.4 and 15.4 nM, respectively. The (R)-enantiomer demonstrates higher ER agonist activity at ERα compared to ERβ.

Names and Identifiers

IUPAC Name	(3R)-3-(4-hydroxyphenyl)-3,4-dihydro-2H-chromen-7-ol
INCHI	InChI=1S/C15H14O3/c16-13-4-1-10(2-5-13)12-7-11-3-6-14(17)8-15(11)18-9-12/h1-6,8,12,16-17H,7,9H2/t12-/m0/s1
InChi Key	ADFCQWZHKCXPAJ-LBPRGKRZSA-N
Canonical SMILES	C1C(COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O
Isomeric SMILES	C1[C@@H](COC2=C1C=CC(=C2)O)C3=CC=C(C=C3)O
PubChem CID	6950272
Molecular Weight	242.27

Solubility

Soluble in ethanol (~20 mg/ml), DMSO (~20 mg/ml), DMF (~10 mg/ml), and ethanol : PBS (1:10, pH 7.2) (~0.1 mg/ml).

Refractive Index

n20D1.65 (Predicted)

Solution Calculators

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Basic Description