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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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R337615-5mg | 5mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $499.90 | |
R337615-25mg | 25mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $1,999.90 | |
R337615-50mg | 50mg | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $3,199.90 |
an optically active version of Venlafaxine
Synonyms | R-Venlafaxine|(R)-Venlafaxine|93413-46-8|1-[(1R)-2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol|Venlafaxine, (R)-|1-[(1R)-2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol|CHEMBL251694|B33212715Z|(R)-1-(2-(dimethylamino)-1-(4-methoxyphen |
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Specifications & Purity | ≥95% |
Storage Temp | Store at 2-8°C |
Shipped In | Wet ice |
Product Description | R-Venlafaxine is an optically active version of Venlafaxine . Venlafaxine is a derivative of phenylethylamine which is reported to facilitate neurotransmission within the central nervous system via blocking the presynaptic reuptake of neuroamines such as serotonin (5-hydroxytryptamine; 5-HT) and noradrenaline (norepinephrine). Velanfaxine is also reported to be a weak inhibitor of dopamine reuptake.|In vitro|studies indicate that Venlafaxine does not demonstrate significant activity for muscarinic, histaminergic or α-1 adrenergic receptors. The metabolism of venlafaxine is reported to occur by cytochrome P450 (CYP) enzyme CYP2D6 yielding O-desmethylvenlafaxine. A lesser metabolite, N-desmethylvenlafaxine is produced by CYP3A4. |
pKa | pKₐ: 9.27 (Predicted) |
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IUPAC Name | 1-[(1R)-2-(dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexan-1-ol |
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INCHI | InChI=1S/C17H27NO2/c1-18(2)13-16(17(19)11-5-4-6-12-17)14-7-9-15(20-3)10-8-14/h7-10,16,19H,4-6,11-13H2,1-3H3/t16-/m0/s1 |
InChi Key | PNVNVHUZROJLTJ-INIZCTEOSA-N |
Canonical SMILES | CN(C)CC(C1=CC=C(C=C1)OC)C2(CCCCC2)O |
Isomeric SMILES | CN(C)C[C@@H](C1=CC=C(C=C1)OC)C2(CCCCC2)O |
RTECS | GV8872620 |
PubChem CID | 9795623 |
Molecular Weight | 277.4 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
Lot Number | Certificate Type | Date | Item |
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E2411335 | Certificate of Analysis | Apr 17, 2024 | R337615 |
E2411336 | Certificate of Analysis | Apr 17, 2024 | R337615 |
E2411337 | Certificate of Analysis | Apr 17, 2024 | R337615 |
E2411338 | Certificate of Analysis | Apr 17, 2024 | R337615 |
E2411339 | Certificate of Analysis | Apr 17, 2024 | R337615 |
E2411340 | Certificate of Analysis | Apr 17, 2024 | R337615 |
Solubility | Soluble in ethanol, methanol, and DMSO. |
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Refractive Index | n20D1.54 (Predicted) |
Specific Rotation[α] | α20D-30.4, c = 0.25 in ethanol |
Boil Point(°C) | ~397.6° C at 760 mmHg (Predicted) |
Melt Point(°C) | 100-102° C |
RTECS | GV8872620 |
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