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RA-V , CAS No.64725-24-2

CAS#: 64725-24-2
Formula: C₄₀H₄₈N₆O₉
Molecular Weight: 756.84
PubChem CID: 429599

Item Number

R649140

Grouped product items
SKU	Size	Availability	Price	Qty
R649140-1mg	1mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$283.90
R649140-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$708.90

Cyclopeptides

View related series

Apoptosis c-Myc Cyclopeptides Neuronal Signaling Notch Stem Cell/Wnt Wnt

Basic Description

Synonyms	Deoxybouvardin\|64725-24-2\|MLS002703037\|AIDS-032100\|NSC259969\|SMR001566845\|24-hydroxy-10-[(4-methoxyphenyl)methyl]-4,7,9,13,15,29-hexamethyl-22-oxa-3,6,9,12,15,29-hexazatetracyclo[14.12.2.218,21.123,27]tritriaconta-18,20,23,25,27(31),32-hexaene-2,5,8,11,14
Biochemical and Physiological Mechanisms	RA-V is a cyclic hexapeptide. RA-V has activity against Wnt , Myc and Notch with IC 50 values of 50, 75, and 93 ng/mL, respectively. RA-V can be used for the research of cancer-related signaling pathways.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Product Description	RA-V is a cyclic hexapeptide. RA-V has activity against Wnt , Myc and Notch with IC 50 values of 50, 75, and 93 ng/mL, respectively. RA-V can be used for the research of cancer-related signaling pathways In Vivo RA-V has activity against Wnt, Myc and Notch with IC 50 values of 50, 75, and 93 ng/mL, respectively . MCE has not independently confirmed the accuracy of these methods. They are for reference only. Form:Solid IC50& Target:IC50: 50 ng/mL (Wnt),75 ng/mL (Myc), 93 ng/mL (Notch)

Associated Targets

GMNN Tbio Geminin 0 Activities

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SMAD3 Tchem Mothers against decapentaplegic homolog 3 0 Activities

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POLI Tchem DNA polymerase iota 0 Activities

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ATXN2 Tbio Ataxin-2 0 Activities

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TDP1 Tchem Tyrosyl-DNA phosphodiesterase 1 0 Activities

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CGA Tbio Glycoprotein hormones alpha chain 0 Activities

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GLP1R Tclin Glucagon-like peptide 1 receptor 0 Activities

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IDH1 Tclin Isocitrate dehydrogenase [NADP] cytoplasmic 0 Activities

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PAX8 Tchem Paired box protein Pax-8 0 Activities

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NFE2L2 Tchem Nuclear factor erythroid 2-related factor 2 0 Activities

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Names and Identifiers

IUPAC Name	24-hydroxy-10-[(4-methoxyphenyl)methyl]-4,7,9,13,15,29-hexamethyl-22-oxa-3,6,9,12,15,29-hexazatetracyclo[14.12.2.218,21.123,27]tritriaconta-18,20,23,25,27(31),32-hexaene-2,5,8,11,14,30-hexone
INCHI	InChI=1S/C40H48N6O9/c1-22-35(48)42-23(2)38(51)44(4)30(18-25-8-13-28(54-7)14-9-25)37(50)43-24(3)39(52)46(6)32-19-26-10-15-29(16-11-26)55-34-21-27(12-17-33(34)47)20-31(36(49)41-22)45(5)40(32)53/h8-17,21-24,30-32,47H,18-20H2,1-7H3,(H,41,49)(H,42,48)(H,43,50)
InChi Key	VXVGFMUNENQGFW-UHFFFAOYSA-N
Canonical SMILES	CC1C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)N(C2CC3=CC=C(C=C3)OC4=C(C=CC(=C4)CC(C(=O)N1)N(C2=O)C)O)C)C)CC5=CC=C(C=C5)OC)C)C
Isomeric SMILES	CC1C(=O)NC(C(=O)N(C(C(=O)NC(C(=O)N(C2CC3=CC=C(C=C3)OC4=C(C=CC(=C4)CC(C(=O)N1)N(C2=O)C)O)C)C)CC5=CC=C(C=C5)OC)C)C
Alternate CAS	64725-24-2
PubChem CID	429599
NSC Number	259969
MeSH Entry Terms	deoxybouvardin;RA V;RA-V
Molecular Weight	756.84

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