ralmitaront , CAS No.2133417-13-5, Agonist of TA 1 receptor

Item Number

R613090

Grouped product items
SKU	Size	Availability	Price	Qty
R613090-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$271.90
R613090-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$948.90

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Basic Description

Synonyms	(s)-5-ethyl-4-methyl-n-(4-(morpholin-2-yl)phenyl)-1h-pyrazole-3-carboxamide \| 5-Ethyl-4-methyl-N-{4-[(2S)-morpholin-2-yl]phenyl}-1H-pyrazole-3-carboxamide \| 5-Ethyl-4-methyl-N-[4-[(2S)-morpholin-2-yl]phenyl]-1H-pyrazole-3-carboxamide \| DTXSID901336976 \| 1
Specifications & Purity	Moligand™
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of TA 1 receptor

Names and Identifiers

IUPAC Name	5-ethyl-4-methyl-N-[4-[(2S)-morpholin-2-yl]phenyl]-1H-pyrazole-3-carboxamide
INCHI	InChI=1S/C17H22N4O2/c1-3-14-11(2)16(21-20-14)17(22)19-13-6-4-12(5-7-13)15-10-18-8-9-23-15/h4-7,15,18H,3,8-10H2,1-2H3,(H,19,22)(H,20,21)/t15-/m1/s1
InChi Key	XHHXGKRFUPEPFM-OAHLLOKOSA-N
Canonical SMILES	CCC1=C(C(=NN1)C(=O)NC2=CC=C(C=C2)C3CNCCO3)C
Isomeric SMILES	CCC1=C(C(=NN1)C(=O)NC2=CC=C(C=C2)[C@H]3CNCCO3)C
Alternate CAS	2133417-13-5
PubChem CID	130429734

PubChem CID

ChEMBL Ligand

CAS Registry No.

References

1. Dedic N, Dworak H, Zeni C, Rutigliano G, Howes OD. (2021) Therapeutic Potential of TAAR1 Agonists in Schizophrenia: Evidence from Preclinical Models and Clinical Studies.. Int J Mol Sci, 22 (24): (1755-70). [PMID:34947997] [10.1021/op500134e]
2. Sparacino G, Verdolini N, Vieta E, Pacchiarotti I. (2022) Existing and emerging pharmacological approaches to the treatment of mania: A critical overview.. Transl Psychiatry, 12 (1): (169). [PMID:35461339] [10.1021/op500134e]
3. Kantrowitz JT. (2021) Trace Amine-Associated Receptor 1 as a Target for the Development of New Antipsychotics: Current Status of Research and Future Directions.. CNS Drugs, 35 (11): (1153-1161). [PMID:34655036] [10.1021/op500134e]
4. Kane JM. (2022) A New Treatment Paradigm: Targeting Trace Amine-Associated Receptor 1 (TAAR1) in Schizophrenia.. J Clin Psychopharmacol, 42 (5 Suppl 1): (S1-S13). [PMID:36099402] [10.1021/op500134e]

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Basic Description