Ranitidine - ≥98%, high purity , CAS No.66357-35-5, Antagonist of H 2 receptor

Item Number
R304317
Grouped product items
SKUSizeAvailabilityPrice Qty
R304317-5g
5g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$9.90
R304317-25g
25g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$16.90
R304317-100g
100g
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$60.90

Basic Description

Specifications & PurityMoligand™, ≥98%
Storage TempStore at -20°C,Argon charged,Desiccated
Shipped InIce chest + Ice pads
GradeMoligand™
Action TypeANTAGONIST
Mechanism of actionAntagonist of H 2 receptor

Associated Targets(Human)

HRH2 Tclin Histamine H2 receptor (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
HRH2 Tclin Histamine H2 receptor (5428 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2D6 Tclin Cytochrome P450 2D6 (33882 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP2C9 Tchem Cytochrome P450 2C9 (32119 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
CYP3A4 Tclin Cytochrome P450 3A4 (53859 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Homo sapiens (32628 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
Caco-2 (12174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC22A1 Tchem Solute carrier family 22 member 1 (646 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCB11 Tchem Bile salt export pump (2311 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
SLC22A2 Tchem Solute carrier family 22 member 2 (261 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

Hdac6 Histone deacetylase 6 (222 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name (E)-1-N'-[2-[[5-[(dimethylamino)methyl]furan-2-yl]methylsulfanyl]ethyl]-1-N-methyl-2-nitroethene-1,1-diamine
INCHI InChI=1S/C13H22N4O3S/c1-14-13(9-17(18)19)15-6-7-21-10-12-5-4-11(20-12)8-16(2)3/h4-5,9,14-15H,6-8,10H2,1-3H3/b13-9+
InChi Key VMXUWOKSQNHOCA-UKTHLTGXSA-N
Canonical SMILES CNC(=C[N+](=O)[O-])NCCSCC1=CC=C(O1)CN(C)C
Isomeric SMILES CN/C(=C\[N+](=O)[O-])/NCCSCC1=CC=C(O1)CN(C)C
PubChem CID 3001055
Molecular Weight 314.39

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

8 results found

Lot NumberCertificate TypeDateItem
L2108117Certificate of AnalysisOct 15, 2024 R304317
L2107796Certificate of AnalysisSep 04, 2024 R304317
C2211155Certificate of AnalysisDec 23, 2021 R304317
C2211435Certificate of AnalysisDec 23, 2021 R304317
C2211436Certificate of AnalysisDec 23, 2021 R304317
E23161127Certificate of AnalysisNov 25, 2021 R304317
K2310020Certificate of AnalysisNov 25, 2021 R304317
B2324026Certificate of AnalysisNov 10, 2021 R304317

Chemical and Physical Properties

SolubilityAcetonitrile (Slightly), DMSO (Slightly), Methanol (Slightly)
SensitivityMoisture sensitive
Boil Point(°C)437.1ºC
Melt Point(°C)69-70°C

Safety and Hazards(GHS)

Pictogram(s) GHS08,   GHS07
Signal Danger
Hazard Statements

H315:Causes skin irritation

H319:Causes serious eye irritation

H335:May cause respiratory irritation

H317:May cause an allergic skin reaction

H334:May cause allergy or asthma symptoms or breathing difficulties if inhaled

Precautionary Statements

P261:Avoid breathing dust/fume/gas/mist/vapors/spray.

P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses if present and easy to do - continue rinsing.

P280:Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352:IF ON SKIN: wash with plenty of water.

P321:Specific treatment (see ... on this label).

P405:Store locked up.

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P284:[In case of inadequate ventilation] Wear respiratory protection.

P271:Use only outdoors or in a well-ventilated area.

P304+P340:IF INHALED: Remove person to fresh air and keep comfortable for breathing.

P403+P233:Store in a well-ventilated place. Keep container tightly closed.

P272:Contaminated work clothing should not be allowed out of the workplace.

P333+P313:IF SKIN irritation or rash occurs: Get medical advice/attention.

P362+P364:Take off contaminated clothing and wash it before reuse.

P264+P265:Wash hands [and …] thoroughly after handling. Do not touch eyes.

P337+P317:If eye irritation persists: Get medical help.

P332+P317:If skin irritation occurs: Get medical help.

P319:Get medical help if you feel unwell.

P342+P316:If experiencing respiratory symptoms: Get emergence medical help immediately.

Related Documents

Citations of This Product

1. Jianrui Niu, Hua Jia, Minghao Yu, Jinyu Zhu, Junjun Ma, Zhuang He, Weizhang Zhong, Yongjiang Hou, Yankai Guo.  (2024)  Nitrogen-rich penicillin residue biochar for activation of peroxymonosulfate for an efficient degradation of tetracycline and its dual-pathway mechanism.  PROCESS SAFETY AND ENVIRONMENTAL PROTECTION,  182  (416).  [PMID:16239728] [10.1016/j.psep.2023.11.066]
2. Jiezhou Pan, Haotian Liao, Guidong Gong, Yunxiang He, Qin Wang, Lang Qin, Yaoyao Zhang, Hirotaka Ejima, Blaise L. Tardy, Joseph J. Richardson, Jiaojiao Shang, Orlando J. Rojas, Yong Zeng, Junling Guo.  (2023)  Supramolecular nanoarchitectonics of phenolic-based nanofiller for controlled diffusion of versatile drugs in hydrogels.  JOURNAL OF CONTROLLED RELEASE,  360  (433).  [PMID:37422124] [10.1016/j.jconrel.2023.07.003]
3. Li Chen, Tahir Maqbool, Ghazanfar Nazir, Congyu Hou, Yanna Xu, Yulong Yang, Xihui Zhang.  (2023)  Peroxymonosulfate activated by composite ceramic membrane for the removal of pharmaceuticals and personal care products (PPCPs) mixture: Insights of catalytic and noncatalytic oxidation.  WATER RESEARCH,  229  (119444).  [PMID:36470049] [10.1016/j.watres.2022.119444]
4. Lin Wang, Qiya Sun, Yicheng Dou, Zhipeng Zhang, Tingting Yan, Yongmei Li.  (2021)  Fabricating a novel ternary recyclable Fe3O4/graphene/sulfur-doped g-C3N4 composite catalyst for enhanced removal of ranitidine under visible-light irradiation and reducing of its N-nitrosodimethylamine formation potential.  JOURNAL OF HAZARDOUS MATERIALS,  413  (125288).  [PMID:33588334] [10.1016/j.jhazmat.2021.125288]

References

1. Jianrui Niu, Hua Jia, Minghao Yu, Jinyu Zhu, Junjun Ma, Zhuang He, Weizhang Zhong, Yongjiang Hou, Yankai Guo.  (2024)  Nitrogen-rich penicillin residue biochar for activation of peroxymonosulfate for an efficient degradation of tetracycline and its dual-pathway mechanism.  PROCESS SAFETY AND ENVIRONMENTAL PROTECTION,  182  (416).  [PMID:16239728] [10.1016/j.psep.2023.11.066]
2. Jiezhou Pan, Haotian Liao, Guidong Gong, Yunxiang He, Qin Wang, Lang Qin, Yaoyao Zhang, Hirotaka Ejima, Blaise L. Tardy, Joseph J. Richardson, Jiaojiao Shang, Orlando J. Rojas, Yong Zeng, Junling Guo.  (2023)  Supramolecular nanoarchitectonics of phenolic-based nanofiller for controlled diffusion of versatile drugs in hydrogels.  JOURNAL OF CONTROLLED RELEASE,  360  (433).  [PMID:37422124] [10.1016/j.jconrel.2023.07.003]
3. Li Chen, Tahir Maqbool, Ghazanfar Nazir, Congyu Hou, Yanna Xu, Yulong Yang, Xihui Zhang.  (2023)  Peroxymonosulfate activated by composite ceramic membrane for the removal of pharmaceuticals and personal care products (PPCPs) mixture: Insights of catalytic and noncatalytic oxidation.  WATER RESEARCH,  229  (119444).  [PMID:36470049] [10.1016/j.watres.2022.119444]
4. Lin Wang, Qiya Sun, Yicheng Dou, Zhipeng Zhang, Tingting Yan, Yongmei Li.  (2021)  Fabricating a novel ternary recyclable Fe3O4/graphene/sulfur-doped g-C3N4 composite catalyst for enhanced removal of ranitidine under visible-light irradiation and reducing of its N-nitrosodimethylamine formation potential.  JOURNAL OF HAZARDOUS MATERIALS,  413  (125288).  [PMID:33588334] [10.1016/j.jhazmat.2021.125288]

Solution Calculators