Rasagiline Mesylate - ≥99%, high purity , Monoamine oxidase B inhibitor, CAS No.161735-79-1, Monoamine oxidase B inhibitor

  • ≥99%
Item Number
R129875
Grouped product items
SKUSizeAvailabilityPrice Qty
R129875-50mg
50mg
In stock
$58.90
R129875-250mg
250mg
In stock
$265.90
R129875-1g
1g
In stock
$955.90
R129875-5g
5g
In stock
$4,301.90

MAO-B inhibitor

Basic Description

Synonyms(1R)-2,3-Dihydro-N-2-propynyl-1H-in den-1-amine methanesulfonate | s2102 | D02562 | MFCD08460604 | 1H-INDEN-1-AMINE, 2,3-DIHYDRO-N-2-PROPYNYL-, (R)-, METHANESULPHONATE | Rasagiline mesylate [USAN] | 1H-Inden-1-amine, 2,3-dihydro-N-2-propyn-1-yl-, (1R)-, m
Specifications & Purity≥99%
Biochemical and Physiological MechanismsRasagiline Mesylate is an antiparkinsonian and a selective irreversible MAO-B inhibitor. Rasagiline mesylate is an effective therapeutic option in early stages of Parkinson′s disease. It improves the motor fluctuations in levodopa-treated patients and may
Storage TempStore at 2-8°C
Shipped InWet ice
Action TypeINHIBITOR
Mechanism of actionMonoamine oxidase B inhibitor
NoteWherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one month. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description

Rasagiline Mesylate is a new MAO-B inhibitor for the treatment of idiopathic Parkinson's disease.
A selective irreversible MAO-B inhibitor

Associated Targets(Human)

MAOB Tclin Amine oxidase [flavin-containing] B (2 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MAOA Tclin Amine oxidase [flavin-containing] A (1 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)
MAOA Tclin Monoamine oxidase A (11911 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ACHE Tclin Acetylcholinesterase (18204 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
MAOB Tclin Monoamine oxidase B (8835 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
BCHE Tclin Butyrylcholinesterase (7174 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCC2 Tchem Canalicular multispecific organic anion transporter 1 (1191 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCB11 Tchem Bile salt export pump (2311 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCC3 Tbio Canalicular multispecific organic anion transporter 2 (718 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID
ABCC4 Tchem Multidrug resistance-associated protein 4 (785 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Associated Targets(non-human)

rep Replicase polyprotein 1ab (378 Activities)
Activity TypeRelationActivity valueUnitsAction TypeJournalPubMed IddoiAssay Aladdin ID

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Names and Identifiers

IUPAC Name methanesulfonic acid;(1R)-N-prop-2-ynyl-2,3-dihydro-1H-inden-1-amine
INCHI InChI=1S/C12H13N.CH4O3S/c1-2-9-13-12-8-7-10-5-3-4-6-11(10)12;1-5(2,3)4/h1,3-6,12-13H,7-9H2;1H3,(H,2,3,4)/t12-;/m1./s1
InChi Key JDBJJCWRXSVHOQ-UTONKHPSSA-N
Canonical SMILES CS(=O)(=O)O.C#CCNC1CCC2=CC=CC=C12
Isomeric SMILES CS(=O)(=O)O.C#CCN[C@@H]1CCC2=CC=CC=C12
WGK Germany 3
PubChem CID 3052775
Molecular Weight 267.34

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

6 results found

Lot NumberCertificate TypeDateItem
B23171125Certificate of AnalysisFeb 23, 2023 R129875
B23171133Certificate of AnalysisFeb 23, 2023 R129875
B23171154Certificate of AnalysisFeb 23, 2023 R129875
B2318010Certificate of AnalysisFeb 23, 2023 R129875
B2318055Certificate of AnalysisFeb 23, 2023 R129875
D1527038Certificate of AnalysisJan 09, 2023 R129875

Chemical and Physical Properties

SolubilityDMSO 53 mg/mL Water 53 mg/mL Ethanol 53 mg/mL
SensitivityHeat Sensitive
Specific Rotation[α]21° (C=2,EtOH)
Melt Point(°C)157 °C

Safety and Hazards(GHS)

Pictogram(s) GHS07
Signal Warning
Hazard Statements

H302:Harmful if swallowed

Precautionary Statements

P501:Dispose of contents/container to ...

P264:Wash hands [and …] thoroughly after handling.

P270:Do not eat, drink or smoke when using this product.

P330:Rinse mouth.

P301+P317:IF SWALLOWED: Get medical help.

WGK Germany 3
Merck Index 8116

Related Documents

Solution Calculators