Endogenous agonist peptide for the ghrelin (GHS) receptor. Stimulates release of growth hormone from the pituitary gland and regulates feeding, growth and energy production.
Storage Temp
Store at -20°C
Shipped In
Ice chest + Ice pads
Grade
Moligand™
Action Type
AGONIST
Mechanism of action
Agonist of ghrelin receptor
Note
Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description
The amino acid sequence：Gly-Ser-Ser(n-octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro- Arg
Associated Targets(Human)
GHSRTclinGrowth hormone secretagogue receptor type 1 (0 Activities)
1.Gui-Bo Liu, Yong-Xia Cheng, Hua-Min Li, Yong Liu, Li-Xin Sun, Qi Wu, Shang-Fu Guo, Ting-Ting Li, Chuan-Ling Dong, Ge Sun. (2023) Ghrelin promotes cardiomyocyte differentiation of adipose tissue‑derived mesenchymal stem cells by DDX17‑mediated regulation of the SFRP4/Wnt/β‑catenin axis. Molecular Medicine Reports, 28 (3):(1-14). [PMID:37449526]
References
1.Li C et al.. (2019) Defined Paraventricular Hypothalamic Populations Exhibit Differential Responses to Food Contingent on Caloric State.. Cell Metab, 29 (3):(681-694.e5). [PMID:30472090]
2.Alhashem F et al.. (2014) Exercise protects against obesity induced semen abnormalities via downregulating stem cell factor, upregulating Ghrelin and normalizing oxidative stress.. EXCLI J, 13 (551-72). [PMID:26417283]
3.Yu Y et al.. (2020) Ghrelin attenuates infectious bursal disease virus-induced early inflammatory response and bursal injury in chicken.. Poult Sci, 99 (11):(5399-5406). [PMID:33142456]
4.Miao H et al.. (2019) Ghrelin Promotes Proliferation and Inhibits Differentiation of 3T3-L1 and Human Primary Preadipocytes.. Front Physiol, 10 (1296). [PMID:31681009]
5.Gui-Bo Liu, Yong-Xia Cheng, Hua-Min Li, Yong Liu, Li-Xin Sun, Qi Wu, Shang-Fu Guo, Ting-Ting Li, Chuan-Ling Dong, Ge Sun. (2023) Ghrelin promotes cardiomyocyte differentiation of adipose tissue‑derived mesenchymal stem cells by DDX17‑mediated regulation of the SFRP4/Wnt/β‑catenin axis. Molecular Medicine Reports, 28 (3):(1-14). [PMID:37449526]
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K1603014