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Rat ghrelin-28 - 95%, high purity , CAS No.258338-12-4, Agonist of ghrelin receptor

1 Citations

Moligand™

≥95%

CAS#: 258338-12-4
Formula: C₁₄₇H₂₄₅N₄₅O₄₂
Molecular Weight: 3314.8
PubChem CID: 44134734

Item Number

G111460

Grouped product items
SKU	Size	Availability	Price	Qty
G111460-1mg	1mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$305.90
G111460-5mg	5mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,376.90

Endogenous GHS agonist

View related series

ghrelin receptor Agonist

Basic Description

Synonyms	GHRELIN, RAT \| Rat ghrelin-28 \| (Ser-3 = Ser(n-octanoyl)) \| DTXSID70657540 \| GSSFLSPEHQKAQQRKESKKPPAKLQPR \| HB2942 \| MFCD07366495 \| C147H245N45O42 \| LS-15550 \| Glycylseryl-N-octanoylserylphenylalanylleucylserylprolyl-alpha-glutamylhistidylglutaminyllysylalanylglutaminylglu
Specifications & Purity	Moligand™, ≥95%
Biochemical and Physiological Mechanisms	Endogenous agonist peptide for the ghrelin (GHS) receptor. Stimulates release of growth hormone from the pituitary gland and regulates feeding, growth and energy production.
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Grade	Moligand™
Action Type	AGONIST
Mechanism of action	Agonist of ghrelin receptor
Note	Wherever possible, you should prepare and use solutions on the same day. However, if you need to make up stock solutions in advance, we recommend that you store the solution as aliquots in tightly sealed vials at -20°C. Generally, these will be useable for up to one week. Before use, and prior to opening the vial we recommend that you allow your product to equilibrate to room temperature for at least 1 hour. Need more advice on solubility, usage and handling? Please visit our frequently asked questions (FAQ) page for more details.
Product Description	The amino acid sequence：Gly-Ser-Ser(n-octanoyl)-Phe-Leu-Ser-Pro-Glu-His-Gln-Lys-Ala-Gln-Gln-Arg-Lys-Glu-Ser-Lys-Lys-Pro-Pro-Ala-Lys-Leu-Gln-Pro- Arg

Names and Identifiers

Isomeric SMILES	CCCCCCCC(=O)N(C(CO)C(=O)NC(CC1=CC=CC=C1)C(=O)NC(CC(C)C)C(=O)NC(CO)C(=O)N2CCCC2C(=O)NC(CCC(=O)O)C(=O)NC(CC3=CNC=N3)C(=O)NC(CCC(=O)N)C(=O)NC(CCCCN)C(=O)NC(C)C(=O)NC(CCC(=O)N)C(=O)NC(CCC(=O)N)C(=O)NC(CCCNC(=N)N)C(=O)NC(CCCCN)C(=O)NC(CCC(=O)O)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(CCCCN)C(=O)N4CCCC4C(=O)N5CCCC5C(=O)NC(C)C(=O)NC(CCCCN)C(=O)NC(CC(C)C)C(=O)NC(CCC(=O)N)C(=O)N6CCCC6C(=O)NC(CCCNC(=N)N)C(=O)O)C(=O)C(CO)NC(=O)CN
PubChem CID	44134734
Molecular Weight	3314.8

CAS Registry No.

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Wikipedia

BindingDB Ligand

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1 results found

Lot Number	Certificate Type	Date	Item
K1603014	Certificate of Analysis	Jun 14, 2024	G111460

Citations of This Product

1. Gui-Bo Liu, Yong-Xia Cheng, Hua-Min Li, Yong Liu, Li-Xin Sun, Qi Wu, Shang-Fu Guo, Ting-Ting Li, Chuan-Ling Dong, Ge Sun. (2023) Ghrelin promotes cardiomyocyte differentiation of adipose tissue‑derived mesenchymal stem cells by DDX17‑mediated regulation of the SFRP4/Wnt/β‑catenin axis. Molecular Medicine Reports, 28 (3): (1-14). [PMID:37449526]

References

1. Li C et al.. (2019) Defined Paraventricular Hypothalamic Populations Exhibit Differential Responses to Food Contingent on Caloric State.. Cell Metab, 29 (3): (681-694.e5). [PMID:30472090]
2. Yu Y et al.. (2020) Ghrelin attenuates infectious bursal disease virus-induced early inflammatory response and bursal injury in chicken.. Poult Sci, 99 (11): (5399-5406). [PMID:33142456]
3. Miao H et al.. (2019) Ghrelin Promotes Proliferation and Inhibits Differentiation of 3T3-L1 and Human Primary Preadipocytes.. Front Physiol, 10 (1296). [PMID:31681009]
4. Alhashem F et al.. (2014) Exercise protects against obesity induced semen abnormalities via downregulating stem cell factor, upregulating Ghrelin and normalizing oxidative stress.. EXCLI J, 13 (551-72). [PMID:26417283]
5. Gui-Bo Liu, Yong-Xia Cheng, Hua-Min Li, Yong Liu, Li-Xin Sun, Qi Wu, Shang-Fu Guo, Ting-Ting Li, Chuan-Ling Dong, Ge Sun. (2023) Ghrelin promotes cardiomyocyte differentiation of adipose tissue‑derived mesenchymal stem cells by DDX17‑mediated regulation of the SFRP4/Wnt/β‑catenin axis. Molecular Medicine Reports, 28 (3): (1-14). [PMID:37449526]

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