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RCI-0879 , CAS No.R613112, Antagonist of UT receptor

Item Number

R613112

Grouped product items
SKU	Size	Availability	Price	Qty
R613112-5mg	5mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$1,334.90
R613112-25mg	25mg	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,000.90

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Basic Description

UTS2R Tchem Urotensin-2 receptor (0 Activities)

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

IUPAC Name	6,7-dichloro-4-{2-[(2S)-4-[2-(morpholin-4-yl)ethanesulfonyl]-2-[(pyrrolidin-1-yl)methyl]piperazin-1-yl]-2-oxoethyl}-3,4-dihydro-2H-1,4-benzoxazin-3-one
INCHI	InChI=1S/C25H35Cl2N5O6S/c26-20-13-22-23(14-21(20)27)38-18-25(34)32(22)17-24(33)31-6-5-30(16-19(31)15-29-3-1-2-4-29)39(35,36)12-9-28-7-10-37-11-8-28/h13-14,19H,1-12,15-18H2/t19-/m0/s1
InChi Key	ABDQSBVMVCODPZ-IBGZPJMESA-N
Canonical SMILES	O=C(N1CCN(C[C@@H]1CN1CCCC1)S(=O)(=O)CCN1CCOCC1)CN1C(=O)COc2c1cc(Cl)c(c2)Cl
PubChem CID	155817517

GPCRdb Ligand	RCI-0879
PubChem CID	155817517

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1. Tandon R, Soni A, Singh RK, Sodhi R, Seth MK, Sinha S, Sahdev S, Dhage G, Das B, Dastidar SG et al.. (2020) Identification of novel Urotensin-II receptor antagonists with potent inhibition of U-II induced pressor response in mice.. Eur J Pharmacol, 886 (13): (173391). [PMID:32745605] [10.1021/op500134e]

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