| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab086986-10μl | 10μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $89.90 | |
| Ab086986-50μl | 50μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $269.90 | |
| Ab086986-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $429.90 | |
| Ab086986-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,399.90 |
Recombinant; Rabbit anti Human ABCG1 Antibody; WB; Unconjugated
| Product Name | ABCG1 Antibody - Primary antibody, specific to ABCG1, Rabbit IgG |
|---|---|
| Synonyms | ATP-binding cassette transporter 8 | EC 7.6.2.- | White protein homolog | ABC transporter 8antibody | ABC8 antibody | ABCG1 antibody | ABCG1_HUMAN antibody | ATP-binding cassette sub family G member 1 antibody | ATP-binding cassette sub-family G member 1 |
| Specifications & Purity | ExactAb™, Validated, Recombinant, 0.3 mg/mL |
| Host species | Rabbit |
| Specificity | ABCG1 |
| Immunogen | A synthetic peptide derived from human ABCG1 (AA 182-195) |
| Positive Control | WB: HeLa, Hep G2 and A549 cell lysates. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description | Rabbit anti Human ABCG1 Antibody, Recombinant, could be used for WB and so on. |
| Isotype | Rabbit IgG |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Recombinant ABCG1 Antibody (Ab086986) - Western Blot
All lanes: Recombinant ABCG1 Antibody (Ab086986) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution
Predicted band size: 76 kDa
Observed band size: 100 kDa
Exposure time: 200.0 s
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB |
1/1000
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1/1000
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Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0809221 | Certificate of Analysis | Aug 05, 2024 | Ab086986 |
| ZJ24F0809220 | Certificate of Analysis | Aug 05, 2024 | Ab086986 |
| 1. Kennedy MA, Venkateswaran A, Tarr PT, Xenarios I, Kudoh J, Shimizu N, Edwards PA. (2001) Characterization of the human ABCG1 gene: liver X receptor activates an internal promoter that produces a novel transcript encoding an alternative form of the protein.. J Biol Chem, 276 (42): (39438-47). [PMID:11500512] [10.1021/op500134e] |
| 2. Venkateswaran A, Repa JJ, Lobaccaro JM, Bronson A, Mangelsdorf DJ, Edwards PA. (2000) Human white/murine ABC8 mRNA levels are highly induced in lipid-loaded macrophages. A transcriptional role for specific oxysterols.. J Biol Chem, 275 (19): (14700-7). [PMID:10799558] [10.1021/op500134e] |
| 3. Chen, H H and 6 more authors.. (1996) Cloning of the cDNA for a human homologue of the Drosophila white gene and mapping to chromosome 21q22.3.. American journal of human genetics, [PMID:8659545] |
| 4. Croop, J M JM and 8 more authors.. (1997) Isolation and characterization of a mammalian homolog of the Drosophila white gene.. Gene, (31): [PMID:9034316] |
| 5. Klucken, J J and 11 more authors.. (2000) ABCG1 (ABC8), the human homolog of the Drosophila white gene, is a regulator of macrophage cholesterol and phospholipid transport.. Proceedings of the National Academy of Sciences of the United States of America, (18): [PMID:10639163] |
| 6. Hattori, M M and 64 more authors.. (2000) The DNA sequence of human chromosome 21.. Nature, (18): [PMID:10830953] |
| 7. Berry, A A and 16 more authors.. (2000) Refined localization of autosomal recessive nonsyndromic deafness DFNB10 locus using 34 novel microsatellite markers, genomic structure, and exclusion of six known genes in the region.. Genomics, (15): [PMID:10950923] |
| 8. Lorkowski, S S and 7 more authors.. (2001) Genomic sequence and structure of the human ABCG1 (ABC8) gene.. Biochemical and biophysical research communications, (12): [PMID:11162488] |
| 9. Porsch-Ozcurumez, M M and 8 more authors.. (2001) The zinc finger protein 202 (ZNF202) is a transcriptional repressor of ATP binding cassette transporter A1 (ABCA1) and ABCG1 gene expression and a modulator of cellular lipid efflux.. The Journal of biological chemistry, (13): [PMID:11279031] |
| 10. Lorkowski, S S and 9 more authors.. (2001) Expression of the ATP-binding cassette transporter gene ABCG1 (ABC8) in Tangier disease.. Biochemical and biophysical research communications, (18): [PMID:11350058] |
| 11. Schmitz, G G, Langmann, T T and Heimerl, S S.. (2001) Role of ABCG1 and other ABCG family members in lipid metabolism.. Journal of lipid research, [PMID:11590207] |
| 12. Kaplan, Rebecca R, Gan, Xiaodong X, Menke, John G JG, Wright, Samuel D SD and Cai, Tian-Quan TQ.. (2002) Bacterial lipopolysaccharide induces expression of ABCA1 but not ABCG1 via an LXR-independent pathway.. Journal of lipid research, [PMID:12032171] |
| 13. Kobayashi, Aya A and 8 more authors.. (2006) Efflux of sphingomyelin, cholesterol, and phosphatidylcholine by ABCG1.. Journal of lipid research, [PMID:16702602] |
| 14. and Lage, Hermann H.. (2006) MDR1/P-glycoprotein (ABCB1) as target for RNA interference-mediated reversal of multidrug resistance.. Current drug targets, [PMID:16842213] |
| 15. Thomas, Anna C AC and 24 more authors.. (2006) ABCA12 is the major harlequin ichthyosis gene.. The Journal of investigative dermatology, [PMID:16902423] |
| 16. and Girardin, François.. (2006) Membrane transporter proteins: a challenge for CNS drug development.. Dialogues in clinical neuroscience, [PMID:17117613] |
| 17. Engel, Thomas T and 7 more authors.. (2007) Expression of ATP binding cassette-transporter ABCG1 prevents cell death by transporting cytotoxic 7beta-hydroxycholesterol.. FEBS letters, (17): [PMID:17408620] |
| 18. Uhlén, Mathias M and 10 more authors.. (2012) Antibody-based protein profiling of the human chromosome 21.. Molecular & cellular proteomics : MCP, [PMID:22042635] |
| 19. Gu, Hong-Mei HM, Wang, Fa-Qi FQ and Zhang, Da-Wei DW.. (2014) Caveolin-1 interacts with ATP binding cassette transporter G1 (ABCG1) and regulates ABCG1-mediated cholesterol efflux.. Biochimica et biophysica acta, [PMID:24576892] |
| 20. Hegyi, Zoltán Z and Homolya, László L.. (2016) Functional Cooperativity between ABCG4 and ABCG1 Isoforms.. PloS one, [PMID:27228027] |
