Recombinant alpha 1 Fetoprotein Antibody - Primary antibody, specific to AFP, IgG

    Application:
  • ELISA
  • Flow Cytometry
  • IF/ICC
  • IHC
  • IP
  • WB
Features and benefits
  • Host species: Rabbit
  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Clone Number: RM1011
  • Conjugation: Unconjugated
Item Number
Ab088271
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab088271-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab088271-50μl
50μl
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$207.90
Ab088271-100μl
100μl
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$327.90
Ab088271-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,007.90

Recombinant (RM1011), Recombinant Anti-alpha 1 Fetoprotein Antibody; IHC, IF/ICC, Flow, WB, IP, ELISA; Unconjugated

Basic Description

Product NameRecombinant alpha 1 Fetoprotein Antibody - Primary antibody, specific to AFP, IgG
SynonymsAFP | Alpha-1-fetoprotein | alpha-fetoglobulin | alpha-Fetoprotein | DSCAM2 | FETA | HP | HPAFP | Afp antibody | AFPD antibody | Alpha fetoglobulin antibody | Alpha fetoprotein antibody | Alpha fetoprotein precursor antibody | Alpha-1-fetoprotein antibody
Specifications & PurityExactAb™, Validated, Recombinant, 0.532 mg/mL
Host speciesRabbit
SpecificityAFP
ImmunogenRecombinant fragment.
Positive ControlIHC-P: Human hepatic carcinoma.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Recombinant Anti-alpha 1 Fetoprotein Antibody, Primary antibody, could be used for IHC, IF/ICC, Flow, WB, IP, ELISA and so on.
Application:
IHC : 1/50 - 1/100
Protein Function
Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties.
Post-translational
Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence. Sulfated.

Product Properties

IsotypeIgG
Light Chain Typekappa
Purification MethodProtein A purified
FormLiquid
Concentration0.532 mg/mL
Storage TempStore at -20°C
Shipped InIce chest + Ice pads
Stability And StorageShipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

Associated Targets(Human)

AFP Tbio Alpha-fetoprotein (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Application

ApplicationDilution info
IHC1/100 - 1/200

">

1/100 - 1/200

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
ZJ23F0700715Certificate of AnalysisApr 25, 2024 Ab088271
ZJ23F0700716Certificate of AnalysisApr 25, 2024 Ab088271

Related Documents

References

1. Yachnin, S S, Hsu, R R, Heinrikson, R L RL and Miller, J B JB..  (1977)  Studies on human alpha-fetoprotein. Isolation and characterization of monomeric and polymeric forms and amino-terminal sequence analysis..  Biochimica et biophysica acta,    (23):   [PMID:70228]
2. Aoyagi, Y Y, Ikenaka, T T and Ichida, F F..  (1977)  Comparative chemical structures of human alpha-fetoproteins from fetal serum and from ascites fluid of a patient with hepatoma..  Cancer research,      [PMID:71198]
3. Aoyagi, Y Y, Ikenaka, T T and Ichida, F F..  (1978)  Copper(II)-binding ability of human alpha-fetoprotein..  Cancer research,      [PMID:80265]
4. Aoyagi, Y Y, Ikenaka, T T and Ichida, F F..  (1979)  alpha-Fetoprotein as a carrier protein in plasma and its bilirubin-binding ability..  Cancer research,      [PMID:89900]
5. Pucci, P P and 6 more authors..  (1991)  Human alpha-fetoprotein primary structure: a mass spectrometric study..  Biochemistry,    (21):   [PMID:1709810]
6. Liu, M C MC, Yu, S S, Sy, J J, Redman, C M CM and Lipmann, F F..  (1985)  Tyrosine sulfation of proteins from the human hepatoma cell line HepG2..  Proceedings of the National Academy of Sciences of the United States of America,      [PMID:2414772]
7. Gibbs, P E PE, Zielinski, R R, Boyd, C C and Dugaiczyk, A A..  (1987)  Structure, polymorphism, and novel repeated DNA elements revealed by a complete sequence of the human alpha-fetoprotein gene..  Biochemistry,    (10):   [PMID:2436661]
8. Sakai, M M and 5 more authors..  (1985)  The human alpha-fetoprotein gene. Sequence organization and the 5' flanking region..  The Journal of biological chemistry,    (25):   [PMID:2580830]
9. Ruoslahti, E E and 5 more authors..  (1974)  Alpha fetoprotein: structure and expression in man and inbred mouse strains under normal conditions and liver injury..  Johns Hopkins medical journal. Supplement,      [PMID:4138095]
10. Beattie, W G WG and Dugaiczyk, A A..  (1982)  Structure and evolution of human alpha-fetoprotein deduced from partial sequence of cloned cDNA..  Gene,      [PMID:6187626]
11. Morinaga, T T, Sakai, M M, Wegmann, T G TG and Tamaoki, T T..  (1983)  Primary structures of human alpha-fetoprotein and its mRNA..  Proceedings of the National Academy of Sciences of the United States of America,      [PMID:6192439]
12. McVey, J H JH and 6 more authors..  (1993)  A G-->A substitution in an HNF I binding site in the human alpha-fetoprotein gene is associated with hereditary persistence of alpha-fetoprotein (HPAFP)..  Human molecular genetics,      [PMID:7684942]
13. Sharony, Reuven R, Zadik, Idit I and Parvari, Ruti R..  (2004)  Congenital deficiency of alpha feto-protein..  European journal of human genetics : EJHG,      [PMID:15280901]
14. Petit, François M FM and 10 more authors..  (2009)  A new mutation in the AFP gene responsible for a total absence of alpha feto-protein on second trimester maternal serum screening for Down syndrome..  European journal of human genetics : EJHG,      [PMID:18854864]
15. Tagliabracci, Vincent S VS and 14 more authors..  (2015)  A Single Kinase Generates the Majority of the Secreted Phosphoproteome..  Cell,    (18):   [PMID:26091039]
16. Thomas R Burkard,Melanie Planyavsky,Ines Kaupe,Florian P Breitwieser,Tilmann Bürckstümmer,Keiryn L Bennett,Giulio Superti-Furga,Jacques Colinge.  (2011-01-29)  Initial characterization of the human central proteome..  BMC systems biology,  (17-17).  [PMID:21269460]

Solution Calculators