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Recombinant alpha 1 Fetoprotein Antibody - Primary antibody, specific to AFP, IgG

Recombinant

Validated

ExactAb™

0.532 mg/mL

Features and benefits

Short Overview:
Recombinant (RM1011), Recombinant Anti-alpha 1 Fetoprotein Antibody; IHC, IF/ICC, Flow, WB, IP, ELISA; Unconjugated
Species reactivity(Reacts with): Human,Mouse,Rat
Isotype: IgG

Application:

ELISA
Flow Cytometry
IF/ICC
IHC
IP
WB

Item Number

Ab088271

Grouped product items
SKU	Size	Availability	Price
Ab088271-10μl	10μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$69.90
Ab088271-50μl	50μl	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$207.90
Ab088271-100μl	100μl	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$327.90
Ab088271-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,007.90

Recombinant (RM1011), Recombinant Anti-alpha 1 Fetoprotein Antibody; IHC, IF/ICC, Flow, WB, IP, ELISA; Unconjugated

View related series

Click to view target information: AFP

Accession#:P02771 AFP AFP; alpha 1 Fetoprotein alpha 1 Fetoprotein Gene ID:174

Basic Description

Product Name	Recombinant alpha 1 Fetoprotein Antibody - Primary antibody, specific to AFP, IgG
Synonyms	AFP; Alpha-1-fetoprotein; alpha-fetoglobulin; alpha-Fetoprotein; DSCAM2; FETA; HP; HPAFP; Afp antibody; AFPD antibody; Alpha fetoglobulin antibody; Alpha fetoprotein antibody; Alpha fetoprotein precursor antibody; Alpha-1-fetoprotein antibody; Alpha-fetog
Specifications & Purity	ExactAb™, Validated, Recombinant, 0.532 mg/mL
Host species	Rabbit
Specificity	AFP
Immunogen	Recombinant fragment.
Positive Control	IHC-P: Human hepatic carcinoma.
Conjugation	Unconjugated
Grade	ExactAb™, Recombinant, Validated
Product Description	Recombinant Anti-alpha 1 Fetoprotein Antibody, Primary antibody, could be used for IHC, IF/ICC, Flow, WB, IP, ELISA and so on. Application: IHC : 1/50 - 1/100 Protein Function Binds copper, nickel, and fatty acids as well as, and bilirubin less well than, serum albumin. Only a small percentage (less than 2%) of the human AFP shows estrogen-binding properties. Post-translational Independent studies suggest heterogeneity of the N-terminal sequence of the mature protein and of the cleavage site of the signal sequence. Sulfated.

Product Properties

Isotype	IgG
Light Chain Type	kappa
Purification Method	Protein A purified
Form	Liquid
Concentration	0.532 mg/mL
Storage Temp	Store at -20°C
Shipped In	Ice chest + Ice pads
Stability And Storage	Shipped at 4°C. Store at +4°C short term (1-2 weeks). Upon delivery aliquot. Store at -20°C long term. Avoid freeze / thaw cycle.

Associated Targets(Human)

AFP Tbio Alpha-fetoprotein (0 Activities)

Discover Target: AFP

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

AFP Tbio Alpha-fetoprotein (0 Activities)

Discover Target: AFP

Activity Type	Relation	Activity value	Units	Action Type	Journal	PubMed Id	doi	Assay Aladdin ID

Application

Dilution info

IHC

1/100 - 1/200

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number	Certificate Type	Date	Item
ZJ23F0700715	Certificate of Analysis	Apr 25, 2024	Ab088271
ZJ23F0700716	Certificate of Analysis	Apr 25, 2024	Ab088271

References

1. Yachnin, S S, Hsu, R R, Heinrikson, R L RL and Miller, J B JB.. (1977) Studies on human alpha-fetoprotein. Isolation and characterization of monomeric and polymeric forms and amino-terminal sequence analysis.. Biochimica et biophysica acta, (23): [PMID:70228]
2. Aoyagi, Y Y, Ikenaka, T T and Ichida, F F.. (1977) Comparative chemical structures of human alpha-fetoproteins from fetal serum and from ascites fluid of a patient with hepatoma.. Cancer research, [PMID:71198]
3. Aoyagi, Y Y, Ikenaka, T T and Ichida, F F.. (1978) Copper(II)-binding ability of human alpha-fetoprotein.. Cancer research, [PMID:80265]
4. Aoyagi, Y Y, Ikenaka, T T and Ichida, F F.. (1979) alpha-Fetoprotein as a carrier protein in plasma and its bilirubin-binding ability.. Cancer research, [PMID:89900]
5. Pucci, P P and 6 more authors.. (1991) Human alpha-fetoprotein primary structure: a mass spectrometric study.. Biochemistry, (21): [PMID:1709810]
6. Liu, M C MC, Yu, S S, Sy, J J, Redman, C M CM and Lipmann, F F.. (1985) Tyrosine sulfation of proteins from the human hepatoma cell line HepG2.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:2414772]
7. Gibbs, P E PE, Zielinski, R R, Boyd, C C and Dugaiczyk, A A.. (1987) Structure, polymorphism, and novel repeated DNA elements revealed by a complete sequence of the human alpha-fetoprotein gene.. Biochemistry, (10): [PMID:2436661]
8. Sakai, M M and 5 more authors.. (1985) The human alpha-fetoprotein gene. Sequence organization and the 5' flanking region.. The Journal of biological chemistry, (25): [PMID:2580830]
9. Ruoslahti, E E and 5 more authors.. (1974) Alpha fetoprotein: structure and expression in man and inbred mouse strains under normal conditions and liver injury.. Johns Hopkins medical journal. Supplement, [PMID:4138095]
10. Beattie, W G WG and Dugaiczyk, A A.. (1982) Structure and evolution of human alpha-fetoprotein deduced from partial sequence of cloned cDNA.. Gene, [PMID:6187626]
11. Morinaga, T T, Sakai, M M, Wegmann, T G TG and Tamaoki, T T.. (1983) Primary structures of human alpha-fetoprotein and its mRNA.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:6192439]
12. McVey, J H JH and 6 more authors.. (1993) A G-->A substitution in an HNF I binding site in the human alpha-fetoprotein gene is associated with hereditary persistence of alpha-fetoprotein (HPAFP).. Human molecular genetics, [PMID:7684942]
13. Sharony, Reuven R, Zadik, Idit I and Parvari, Ruti R.. (2004) Congenital deficiency of alpha feto-protein.. European journal of human genetics : EJHG, [PMID:15280901]
14. Petit, François M FM and 10 more authors.. (2009) A new mutation in the AFP gene responsible for a total absence of alpha feto-protein on second trimester maternal serum screening for Down syndrome.. European journal of human genetics : EJHG, [PMID:18854864]
15. Tagliabracci, Vincent S VS and 14 more authors.. (2015) A Single Kinase Generates the Majority of the Secreted Phosphoproteome.. Cell, (18): [PMID:26091039]
16. Thomas R Burkard,Melanie Planyavsky,Ines Kaupe,Florian P Breitwieser,Tilmann Bürckstümmer,Keiryn L Bennett,Giulio Superti-Furga,Jacques Colinge. (2011-01-29) Initial characterization of the human central proteome.. BMC systems biology, 5 (17-17). [PMID:21269460]

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