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Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Recombinant; Rabbit anti Human ANXA2 Antibody; WB, ICC, IF; Unconjugated
SKU | Size | Availability | Price | Qty |
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Ab088973-10μl | 10μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $66.90 | |
Ab088973-50μl | 50μl | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $198.90 | |
Ab088973-100μl | 100μl | Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience! | $300.90 | |
Ab088973-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,250.90 |
Recombinant; Rabbit anti Human ANXA2 Antibody; WB, ICC, IF; Unconjugated
Product Name | Recombinant ANXA2 Antibody - Primary antibody, for WB,IF,ICC various applications, from Human, generated in Rabbit, specific to ANXA2, Rabbit IgG |
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Synonyms | Annexin A2 antibody; Annexin II antibody; Annexin II,heavy chain antibody; Annexin-2 antibody; ANX 2 antibody; ANX2 antibody; ANX2L4 antibody; ANXA2 antibody; ANXA2_HUMAN antibody; arylsulfatase B antibody; CAL1H antibody; Calpactin I heavy chain antibody |
Specifications & Purity | ExactAb™, Validated, Recombinant, 0.3 mg/mL |
Host Species | Rabbit |
Host species | Rabbit |
Specificity | ANXA2 |
Application | WB,IF,ICC |
Immunogen | A synthetic peptide derived from human Annexin A2 (AA 33-46). |
Positive Control | WB: NIH/3T3, HeLa, A549, C6 lysates. IF: HeLa cells. |
Conjugation | Unconjugated |
Grade | ExactAb™, Recombinant, Validated |
Product Description | Rabbit anti Human ANXA2 Antibody, Recombinant, could be used to WB, ICC, IF and so on. Application WB: 1/500-1/1000; ICC/IF: 1/50-1/200; Purity Antigen affinity purification Protein Function Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response. Post-translational Phosphorylation of Tyr-24 enhances heat stress-induced translocation to the cell surface. ISGylated. |
Antibody Type | Primary antibody |
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Clonality | Recombinant |
Isotype | Rabbit IgG |
SDS-PAGE | 150 kDa |
Purification Method | Antigen affinity purification |
Source | Cell supernatant |
Form | Liquid |
Concentration | 0.3 mg/mL |
Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
Shipped In | Ice chest + Ice pads |
Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
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Application | Dilution info |
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WB | 1/500-1/1000 |
ICC/IF |
1/50-1/200
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Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
Lot Number | Certificate Type | Date | Item |
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ZJ23F0700721 | Certificate of Analysis | Jul 31, 2023 | Ab088973 |
ZJ23F0700720 | Certificate of Analysis | Jul 31, 2023 | Ab088973 |
1. Manik Goel,Adam E Sienkiewicz,Renata Picciani,Richard K Lee,Sanjoy K Bhattacharya. (2011-09-03) Cochlin induced TREK-1 co-expression and annexin A2 secretion: role in trabecular meshwork cell elongation and motility.. PloS one, 6 ((8)): (e23070-e23070). [PMID:21886777] |
2. Francis Impens,Lilliana Radoshevich,Pascale Cossart,David Ribet. (2014-08-13) Mapping of SUMO sites and analysis of SUMOylation changes induced by external stimuli.. Proceedings of the National Academy of Sciences of the United States of America, 111 ((34)): (12432-12437). [PMID:25114211] |
3. Reddy TR, Li C, Guo X, Myrvang HK, Fischer PM, Dekker LV.. (2011) Design, synthesis, and structure-activity relationship exploration of 1-substituted 4-aroyl-3-hydroxy-5-phenyl-1H-pyrrol-2(5H)-one analogues as inhibitors of the annexin A2-S100A10 protein interaction.. J Med Chem, 54 (7): (2080-2094). [PMID:21375334] |
4. Jindal, H K HK, Chaney, W G WG, Anderson, C W CW, Davis, R G RG and Vishwanatha, J K JK.. (1991) The protein-tyrosine kinase substrate, calpactin I heavy chain (p36), is part of the primer recognition protein complex that interacts with DNA polymerase alpha.. The Journal of biological chemistry, (15): [PMID:1825830] |
5. Spano, F F, Raugei, G G, Palla, E E, Colella, C C and Melli, M M.. (1990) Characterization of the human lipocortin-2-encoding multigene family: its structure suggests the existence of a short amino acid unit undergoing duplication.. Gene, (15): [PMID:2174397] |
6. Gould, K L KL, Woodgett, J R JR, Isacke, C M CM and Hunter, T T.. (1986) The protein-tyrosine kinase substrate p36 is also a substrate for protein kinase C in vitro and in vivo.. Molecular and cellular biology, [PMID:2946940] |
7. Huang, K S KS and 9 more authors.. (1986) Two human 35 kd inhibitors of phospholipase A2 are related to substrates of pp60v-src and of the epidermal growth factor receptor/kinase.. Cell, (18): [PMID:3013422] |
8. Hyatt, S L SL, Liao, L L, Chapline, C C and Jaken, S S.. (1994) Identification and characterization of alpha-protein kinase C binding proteins in normal and transformed REF52 cells.. Biochemistry, (8): [PMID:8110754] |
9. Wright, J F JF, Kurosky, A A and Wasi, S S.. (1994) An endothelial cell-surface form of annexin II binds human cytomegalovirus.. Biochemical and biophysical research communications, (15): [PMID:8117306] |
10. Emans, N N and 6 more authors.. (1993) Annexin II is a major component of fusogenic endosomal vesicles.. The Journal of cell biology, [PMID:8449982] |
11. Burger, A A and 10 more authors.. (1996) The crystal structure and ion channel activity of human annexin II, a peripheral membrane protein.. Journal of molecular biology, (12): [PMID:8636985] |
12. MacLeod, Travis J TJ, Kwon, Mijung M, Filipenko, Nolan R NR and Waisman, David M DM.. (2003) Phospholipid-associated annexin A2-S100A10 heterotetramer and its subunits: characterization of the interaction with tissue plasminogen activator, plasminogen, and plasmin.. The Journal of biological chemistry, (11): [PMID:12730231] |
13. Kirshner, Julia J, Schumann, Detlef D and Shively, John E JE.. (2003) CEACAM1, a cell-cell adhesion molecule, directly associates with annexin II in a three-dimensional model of mammary morphogenesis.. The Journal of biological chemistry, (12): [PMID:14522961] |
14. Andersen, Jens S JS and 5 more authors.. (2003) Proteomic characterization of the human centrosome by protein correlation profiling.. Nature, (4): [PMID:14654843] |
15. Deora, Arunkumar B AB, Kreitzer, Geri G, Jacovina, Andrew T AT and Hajjar, Katherine A KA.. (2004) An annexin 2 phosphorylation switch mediates p11-dependent translocation of annexin 2 to the cell surface.. The Journal of biological chemistry, (15): [PMID:15302870] |
16. Giannakopoulos, Nadia V NV and 9 more authors.. (2005) Proteomic identification of proteins conjugated to ISG15 in mouse and human cells.. Biochemical and biophysical research communications, (21): [PMID:16139798] |
17. Zody, Michael C MC and 68 more authors.. (2006) Analysis of the DNA sequence and duplication history of human chromosome 15.. Nature, (30): [PMID:16572171] |
18. Chi, An A and 16 more authors.. (2006) Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.. Journal of proteome research, [PMID:17081065] |
19. Bechtel, Stephanie S and 18 more authors.. (2007) The full-ORF clone resource of the German cDNA Consortium.. BMC genomics, (31): [PMID:17974005] |
20. Mayer, Gaétan G, Poirier, Steve S and Seidah, Nabil G NG.. (2008) Annexin A2 is a C-terminal PCSK9-binding protein that regulates endogenous low density lipoprotein receptor levels.. The Journal of biological chemistry, (14): [PMID:18799458] |
21. Seidah, Nabil G NG and 10 more authors.. (2012) Annexin A2 is a natural extrahepatic inhibitor of the PCSK9-induced LDL receptor degradation.. PloS one, [PMID:22848640] |
22. Zhou, Houjiang H and 6 more authors.. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome.. Journal of proteome research, (4): [PMID:23186163] |
23. Bian, Yangyang Y and 9 more authors.. (2014) An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.. Journal of proteomics, (16): [PMID:24275569] |
24. Ly, Kévin K and 9 more authors.. (2014) Annexin A2 reduces PCSK9 protein levels via a translational mechanism and interacts with the M1 and M2 domains of PCSK9.. The Journal of biological chemistry, (20): [PMID:24808179] |
25. Somarajan, Sudha R SR and 5 more authors.. (2014) Annexin A2 mediates Mycoplasma pneumoniae community-acquired respiratory distress syndrome toxin binding to eukaryotic cells.. mBio, (19): [PMID:25139904] |
26. Bai, Dou-Sheng DS and 11 more authors.. (2016) UBAP2 negatively regulates the invasion of hepatocellular carcinoma cell by ubiquitinating and degradating Annexin A2.. Oncotarget, (31): [PMID:27121050] |
27. Thomas R Burkard,Melanie Planyavsky,Ines Kaupe,Florian P Breitwieser,Tilmann Bürckstümmer,Keiryn L Bennett,Giulio Superti-Furga,Jacques Colinge. (2011-01-29) Initial characterization of the human central proteome.. BMC systems biology, 5 (17-17). [PMID:21269460] |