Recombinant ApoER2 Antibody - Primary antibody, specific to ApoER2, Rabbit IgG

    Application:
  • WB
Features and benefits
  • Host species: Rabbit
  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
Item Number
Ab089253
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab089253-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab089253-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
Ab089253-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$319.90
Ab089253-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,099.90

Recombinant; Rabbit anti Human ApoER2 Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant ApoER2 Antibody - Primary antibody, specific to ApoER2, Rabbit IgG
SynonymsAPOER2 antibody | Apolipoprotein E receptor 2 antibody | low density lipoprotein receptor-related protein 8 antibody | Low-density lipoprotein receptor-related protein 8 antibody | LRP-8 antibody | LRP8 antibody | LRP8_HUMAN antibody | LRP8 | MCI1 | LRP-8
Specifications & PurityExactAb™, Validated, KD, Recombinant, Lot by Lot
Host speciesRabbit
SpecificityApoER2
ImmunogenA synthetic peptide derived from human ApoER2 (AA 900-963).
Positive ControlWB: SK-N-SH and C6 cell lysates.
ConjugationUnconjugated
GradeExactAb™, KD Validation, Recombinant, Validated
Product Description

Rabbit anti Human ApoER2 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/2000
Protein Function:
Cell surface receptor for Reelin (RELN) and apolipoprotein E (apoE)-containing ligands. LRP8 participates in transmitting the extracellular Reelin signal to intracellular signaling processes, by binding to DAB1 on its cytoplasmic tail. Reelin acts via both the VLDL receptor (VLDLR) and LRP8 to regulate DAB1 tyrosine phosphorylation and microtubule function in neurons. LRP8 has higher affinity for Reelin than VLDLR. LRP8 is thus a key component of the Reelin pathway which governs neuronal layering of the forebrain during embryonic brain development. Binds the endoplasmic reticulum resident receptor-associated protein (RAP). Binds dimers of beta 2-glycoprotein I and may be involved in the suppression of platelet aggregation in the vasculature. Highly expressed in the initial segment of the epididymis, where it affects the functional expression of clusterin and phospholipid hydroperoxide glutathione peroxidase (PHGPx), two proteins required for sperm maturation. May also function as an endocytic receptor.

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
ConcentrationLot by Lot
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant ApoER2 Antibody (Ab089253) - Western Blot
All lanes: Recombinant ApoER2 Antibody (Ab089253) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 106 kDa
Observed band size: 95 kDa
Exposure time: 39.9 s

Associated Targets(Human)

LRP8 Tbio Low-density lipoprotein receptor-related protein 8 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB 1/500-1/2000

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1/500-1/2000

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0607503Certificate of AnalysisJun 27, 2024 Ab089253
ZJ24F0607502Certificate of AnalysisJun 27, 2024 Ab089253

Related Documents

Solution Calculators