Recombinant Apolipoprotein L1/APOL1 Antibody - Primary antibody, specific to Apolipoprotein L1/APOL1, Rabbit IgG

    Application:
  • WB
Features and benefits
  • Host species: Rabbit
  • Species reactivity(Reacts with): Human
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
Item Number
Ab089364
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab089364-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$79.90

Recombinant; Rabbit anti Human Apolipoprotein L1/APOL1 Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant Apolipoprotein L1/APOL1 Antibody - Primary antibody, specific to Apolipoprotein L1/APOL1, Rabbit IgG
SynonymsAPO Lantibody | Apo-L antibody | ApoL antibody | APOL I antibody | ApoL-I antibody | APOL1 antibody | APOL1_HUMAN antibody | APOLI antibody | Apolipoprotein L antibody | Apolipoprotein L I antibody | Apolipoprotein L-I antibody | Apolipoprotein L1 antibod
Specifications & PurityExactAb™, Validated, Recombinant, 0.5 mg/mL
Host speciesRabbit
SpecificityApolipoprotein L1/APOL1
ImmunogenA synthetic peptide derived from human APOL1 (AA 303-345)
Positive ControlWB: A431 cell lysate.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Note20μl卖完停产,不再备货
Product Description

Rabbit anti Human Apolipoprotein L1/APOL1 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function:
May play a role in lipid exchange and transport throughout the body. May participate in reverse cholesterol transport from peripheral cells to the liver.

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration0.5 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant Apolipoprotein L1/APOL1 Antibody (Ab089364) - Western Blot
All lanes: Recombinant Apolipoprotein L1/APOL1 Antibody (Ab089364) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 44 kDa
Observed band size: 44 kDa
Exposure time: 30.0 s

Associated Targets(Human)

APOL1 Tbio Apolipoprotein L1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Application

ApplicationDilution info
WB1/500-1/1000

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1/500-1/1000

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0708986Certificate of AnalysisJul 31, 2024 Ab089364
ZJ24F0708985Certificate of AnalysisJul 31, 2024 Ab089364

Related Documents

References

1. Sabnis RW.  (2020)  Novel APOL1 Inhibitors for Treating Kidney Diseases..  ACS Med Chem Lett,  11  (12.0): (2352-2353).  [PMID:33335649] [10.1021/acsmedchemlett.0c00531]
2. Duchateau, P N PN and 7 more authors..  (1997)  Apolipoprotein L, a new human high density lipoprotein apolipoprotein expressed by the pancreas. Identification, cloning, characterization, and plasma distribution of apolipoprotein L..  The Journal of biological chemistry,    (10):   [PMID:9325276]
3. Dunham, I I and 24 more authors..  (1999)  The DNA sequence of human chromosome 22..  Nature,    (2):   [PMID:10591208]
4. Duchateau, P N PN, Pullinger, C R CR, Cho, M H MH, Eng, C C and Kane, J P JP..  (2001)  Apolipoprotein L gene family: tissue-specific expression, splicing, promoter regions; discovery of a new gene..  Journal of lipid research,      [PMID:11290834]
5. Page, N M NM, Butlin, D J DJ, Lomthaisong, K K and Lowry, P J PJ..  (2001)  The human apolipoprotein L gene cluster: identification, classification, and sites of distribution..  Genomics,    (15):   [PMID:11374903]
6. Monajemi, Houshang H, Fontijn, Ruud D RD, Pannekoek, Hans H and Horrevoets, Anton J G AJ..  (2002)  The apolipoprotein L gene cluster has emerged recently in evolution and is expressed in human vascular tissue..  Genomics,      [PMID:11944986]
7. Liu, Tao T and 6 more authors..  ()  Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry..  Journal of proteome research,      [PMID:16335952]
8. Sjöblom, Tobias T and 28 more authors..  (2006)  The consensus coding sequences of human breast and colorectal cancers..  Science (New York, N.Y.),    (13):   [PMID:16959974]
9. Tzur, Shay S and 10 more authors..  (2010)  Missense mutations in the APOL1 gene are highly associated with end stage kidney disease risk previously attributed to the MYH9 gene..  Human genetics,      [PMID:20635188]
10. Genovese, Giulio G and 17 more authors..  (2010)  Association of trypanolytic ApoL1 variants with kidney disease in African Americans..  Science (New York, N.Y.),    (13):   [PMID:20647424]
11. Bian, Yangyang Y and 9 more authors..  (2014)  An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome..  Journal of proteomics,    (16):   [PMID:24275569]
12. Tagliabracci, Vincent S VS and 14 more authors..  (2015)  A Single Kinase Generates the Majority of the Secreted Phosphoproteome..  Cell,    (18):   [PMID:26091039]
13. Olabisi, Opeyemi A OA and Heneghan, John F JF..  (2017)  APOL1 Nephrotoxicity: What Does Ion Transport Have to Do With It?.  Seminars in nephrology,      [PMID:29110762]

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