Recombinant BAP1 Antibody - Primary antibody, specific to BAP1, Rabbit IgG

    Application:
  • WB
Features and benefits
  • Host species: Rabbit
  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
Item Number
Ab090597
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab090597-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab090597-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
Ab090597-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90
Ab090597-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,699.90

Recombinant; Rabbit anti Human BAP1 Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant BAP1 Antibody - Primary antibody, specific to BAP1, Rabbit IgG
SynonymsBAP1 | BAP 1 | BAP1_HUMAN | BRCA 1 associated protein 1 | BRCA1 associated protein 1 | BRCA1-associated protein 1 | Cerebral protein 13 | Cerebral protein 6 | DKFZp686N04275 | FLJ35406 | FLJ37180 | HUCEP 13 | Hucep 6 | HUCEP13 | Hucep6 | KIAA0272 | TPDS |
Specifications & PurityExactAb™, Validated, Recombinant, 0.6 mg/mL
Host speciesRabbit
SpecificityBAP1
ImmunogenRecombinant protein of human BAP1 (AA 35-185)
Positive ControlWB: A375, A549, MOLT-4, U-2 OS, NIH/3T3 and C6 cell lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human BAP1 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function
Deubiquitinating enzyme that plays a key role in chromatin by mediating deubiquitination of histone H2A and HCFC1. Catalytic component of the PR-DUB complex, a complex that specifically mediates deubiquitination of histone H2A monoubiquitinated at 'Lys-119' (H2AK119ub1). Does not deubiquitinate monoubiquitinated histone H2B. Acts as a regulator of cell growth by mediating deubiquitination of HCFC1 N-terminal and C-terminal chains, with some specificity toward 'Lys-48'-linked polyubiquitin chains compared to 'Lys-63'-linked polyubiquitin chains. Deubiquitination of HCFC1 does not lead to increase stability of HCFC1. Interferes with the BRCA1 and BARD1 heterodimer activity by inhibiting their ability to mediate ubiquitination and autoubiquitination. It however does not mediate deubiquitination of BRCA1 and BARD1. Acts as a tumor suppressor.

Product Properties

IsotypeRabbit IgG
Purification MethodAntigen affinity purified
FormLiquid
Concentration0.6 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant BAP1 Antibody (Ab090597) - Western Blot
All lanes: Recombinant BAP1 Antibody (Ab090597) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 80 kDa
Observed band size: 94 kDa
Exposure time: 75.1 s

Associated Targets(Human)

BAP1 Tbio Ubiquitin carboxyl-terminal hydrolase BAP1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Application

ApplicationDilution info
WB 1/500-1/1000

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1/500-1/1000

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0607020Certificate of AnalysisJun 19, 2024 Ab090597
ZJ24F0607019Certificate of AnalysisJun 19, 2024 Ab090597

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