| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab091424-10μl | 10μl | In stock | $69.90 | |
| Ab091424-50μl | 50μl | In stock | $209.90 | |
| Ab091424-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $299.90 | |
| Ab091424-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,399.90 |
Recombinant; Rabbit anti Human BMP4 Antibody; WB, ICC, IF; Unconjugated
| Product Name | Recombinant BMP4 Antibody - Primary antibody, specific to BMP4, Rabbit IgG |
|---|---|
| Synonyms | zgc:100779 antibody | BMP 2B antibody | BMP 4 antibody | BMP-2B antibody | BMP-4 antibody | BMP2B antibody | BMP2B1 antibody | BMP4 antibody | BMP4_HUMAN antibody | Bone morphogenetic protein 2B antibody | Bone morphogenetic protein 4 antibody | DVR4 anti |
| Specifications & Purity | ExactAb™, Validated, Recombinant, 0.5 mg/mL |
| Host species | Rabbit |
| Specificity | BMP4 |
| Immunogen | A synthetic peptide derived from human BMP4 (AA 385-397) |
| Positive Control | WB: K562, A431, A459 and HeLa cell lysates. ICC/IF: Hep G2 cells. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description | Rabbit anti Human BMP4 Antibody, Recombinant, could be used for WB, ICC/IF and so on. Application
Protein Function Induces cartilage and bone formation. Also act in mesoderm induction, tooth development, limb formation and fracture repair. Acts in concert with PTHLH/PTHRP to stimulate ductal outgrowth during embryonic mammary development and to inhibit hair follicle induction. |
| Isotype | Rabbit IgG |
|---|---|
| SDS-PAGE | 150 kDa |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Recombinant BMP4 Antibody (Ab091424) - Western Blot
All lanes: Recombinant BMP4 Antibody (Ab091424) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 47 kDa
Observed band size: 45 kDa
Exposure time: 50.6 s
Recombinant BMP4 Antibody (Ab091424) - IF/ICC
Immunocytochemistry analysis of BMP4 (green) in Hep G2 using Recombinant BMP4 Antibody (Ab091424), and cells were counterstained with DAPI (blue).
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/500-1/1000"> 1/500-1/1000 |
| IF/ICC |
1/50-1/200
">
1/50-1/200
|
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0102407 | Certificate of Analysis | Jan 10, 2024 | Ab091424 |
| ZJ24F0102408 | Certificate of Analysis | Jan 10, 2024 | Ab091424 |
| 1. Wozney, J M JM and 7 more authors.. (1988) Novel regulators of bone formation: molecular clones and activities.. Science (New York, N.Y.), (16): [PMID:3201241] |
| 2. Oida, S S, Iimura, T T, Maruoka, Y Y, Takeda, K K and Sasaki, S S.. (1995) Cloning and sequence of bone morphogenetic protein 4 (BMP-4) from a human placental cDNA library.. DNA sequence : the journal of DNA sequencing and mapping, [PMID:7579580] |
| 3. ten Dijke, P P and 8 more authors.. (1994) Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4.. The Journal of biological chemistry, (24): [PMID:8006002] |
| 4. Shore, E M EM and 10 more authors.. (1998) The human bone morphogenetic protein 4 (BMP-4) gene: molecular structure and transcriptional regulation.. Calcified tissue international, [PMID:9701626] |
| 5. Felder, Bärbel B and 6 more authors.. (2002) Evaluation of BMP4 and its specific inhibitor NOG as candidates in human neural tube defects (NTDs).. European journal of human genetics : EJHG, [PMID:12404109] |
| 6. Yanagita, Motoko M and 9 more authors.. (2004) USAG-1: a bone morphogenetic protein antagonist abundantly expressed in the kidney.. Biochemical and biophysical research communications, (2): [PMID:15020244] |
| 7. Bakrania, Preeti P and 20 more authors.. (2008) Mutations in BMP4 cause eye, brain, and digit developmental anomalies: overlap between the BMP4 and hedgehog signaling pathways.. American journal of human genetics, [PMID:18252212] |
| 8. Weber, Stefanie S and 17 more authors.. (2008) SIX2 and BMP4 mutations associate with anomalous kidney development.. Journal of the American Society of Nephrology : JASN, [PMID:18305125] |
| 9. Sengle, Gerhard G and 7 more authors.. (2008) Targeting of bone morphogenetic protein growth factor complexes to fibrillin.. The Journal of biological chemistry, (16): [PMID:18339631] |
| 10. Suzuki, Satoshi S and 26 more authors.. (2009) Mutations in BMP4 are associated with subepithelial, microform, and overt cleft lip.. American journal of human genetics, [PMID:19249007] |
| 11. Tagliabracci, Vincent S VS and 14 more authors.. (2015) A Single Kinase Generates the Majority of the Secreted Phosphoproteome.. Cell, (18): [PMID:26091039] |
| 12. Jin, Xin X and 9 more authors.. (2017) Fstl1 Promotes Glioma Growth Through the BMP4/Smad1/5/8 Signaling Pathway.. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, [PMID:29212066] |
