Recombinant; Rabbit anti Human BST2/Tetherin Antibody; WB; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab091772-10μl | 10μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 | |
| Ab091772-50μl | 50μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $199.90 | |
| Ab091772-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $299.90 | |
| Ab091772-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,699.90 |
Recombinant; Rabbit anti Human BST2/Tetherin Antibody; WB; Unconjugated
| Product Name | Recombinant BST2/Tetherin Antibody - Primary antibody, specific to BST2, Rabbit IgG |
|---|---|
| Synonyms | BST-2 | HM1.24 antigen | Tetherin | bone marrow stromal antigen 2 | bone marrow stromal cell antigen 2 | BST2 | BST-2 | CD317 antigen | CD317 | HM1.24 Antigen | NPC-A-7 | PDCA-1 | Tetherinl | Bone marrow stromal antigen 2 antibody | Bone marrow stromal ce |
| Specifications & Purity | ExactAb™, Validated, Recombinant, 0.25 mg/mL |
| Host species | Rabbit |
| Specificity | BST2 |
| Immunogen | A synthetic peptide derived from human BST2 (AA 100-150) |
| Positive Control | WB: MOLT-4, U937, NIH/3T3 and C6 cell lysates. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description | Rabbit anti Human BST2/Tetherin Antibody, Recombinant, could be used for WB and so on. |
| Isotype | Rabbit IgG |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | 0.25 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Recombinant BST2/Tetherin Antibody (Ab091772) - Western Blot
All lanes: Recombinant BST2/Tetherin Antibody (Ab091772) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/30000 dilution
Predicted band size: 20 kDa
Observed band size: 45, 48 kDa
Exposure time: 47.2 s
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/500-1/1000 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0708921 | Certificate of Analysis | Jul 29, 2024 | Ab091772 |
| ZJ24F0708920 | Certificate of Analysis | Jul 29, 2024 | Ab091772 |
| 1. Ishikawa, J J and 9 more authors.. (1995) Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth.. Genomics, (10): [PMID:7607676] |
| 2. Ohtomo, T T and 10 more authors.. (1999) Molecular cloning and characterization of a surface antigen preferentially overexpressed on multiple myeloma cells.. Biochemical and biophysical research communications, (19): [PMID:10329429] |
| 3. Grimwood, Jane J and 97 more authors.. (2004) The DNA sequence and biology of human chromosome 19.. Nature, (1): [PMID:15057824] |
| 4. Vidal-Laliena, Miriam M and 5 more authors.. () Characterization of antibodies submitted to the B cell section of the 8th Human Leukocyte Differentiation Antigens Workshop by flow cytometry and immunohistochemistry.. Cellular immunology, [PMID:16157322] |
| 5. Elortza, Felix F and 7 more authors.. (2006) Modification-specific proteomics of plasma membrane proteins: identification and characterization of glycosylphosphatidylinositol-anchored proteins released upon phospholipase D treatment.. Journal of proteome research, [PMID:16602701] |
| 6. Neil, Stuart J D SJ, Zang, Trinity T and Bieniasz, Paul D PD.. (2008) Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu.. Nature, (24): [PMID:18200009] |
| 7. Jouvenet, Nolwenn N and 8 more authors.. (2009) Broad-spectrum inhibition of retroviral and filoviral particle release by tetherin.. Journal of virology, [PMID:19036818] |
| 8. Kaletsky, Rachel L RL, Francica, Joseph R JR, Agrawal-Gamse, Caroline C and Bates, Paul P.. (2009) Tetherin-mediated restriction of filovirus budding is antagonized by the Ebola glycoprotein.. Proceedings of the National Academy of Sciences of the United States of America, (24): [PMID:19179289] |
| 9. Wollscheid, Bernd B and 7 more authors.. (2009) Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.. Nature biotechnology, [PMID:19349973] |
| 10. Cao, Wei W and 14 more authors.. (2009) Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction.. The Journal of experimental medicine, (6): [PMID:19564354] |
| 11. Andrew, Amy J AJ, Miyagi, Eri E, Kao, Sandra S and Strebel, Klaus K.. (2009) The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to Vpu.. Retrovirology, (8): [PMID:19737401] |
| 12. Le Tortorec, Anna A and Neil, Stuart J D SJ.. (2009) Antagonism to and intracellular sequestration of human tetherin by the human immunodeficiency virus type 2 envelope glycoprotein.. Journal of virology, [PMID:19740980] |
| 13. Iwabu, Yukie Y and 7 more authors.. (2009) HIV-1 accessory protein Vpu internalizes cell-surface BST-2/tetherin through transmembrane interactions leading to lysosomes.. The Journal of biological chemistry, (11): [PMID:19837671] |
| 14. Perez-Caballero, David D and 6 more authors.. (2009) Tetherin inhibits HIV-1 release by directly tethering virions to cells.. Cell, (30): [PMID:19879838] |
| 15. Gupta, Ravindra K and Towers, Greg J.. (2009) A tail of Tetherin: how pandemic HIV-1 conquered the world.. Cell host & microbe, (19): [PMID:19917491] |
| 16. Hinz, Andreas A and 10 more authors.. (2010) Structural basis of HIV-1 tethering to membranes by the BST-2/tetherin ectodomain.. Cell host & microbe, (22): [PMID:20399176] |
| 17. Pardieu, Claire C and 8 more authors.. (2010) The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin.. PLoS pathogens, (15): [PMID:20419159] |
| 18. Radoshitzky, Sheli R SR and 14 more authors.. (2010) Infectious Lassa virus, but not filoviruses, is restricted by BST-2/tetherin.. Journal of virology, [PMID:20686043] |
| 19. Evans, David T; Serra-Moreno, Ruth; Singh, Rajendra K and Guatelli, John C.. (2010) BST-2/tetherin: a new component of the innate immune response to enveloped viruses.. Trends in microbiology, [PMID:20688520] |
| 20. Schubert, Heidi L HL and 8 more authors.. (2010) Structural and functional studies on the extracellular domain of BST2/tetherin in reduced and oxidized conformations.. Proceedings of the National Academy of Sciences of the United States of America, (19): [PMID:20880831] |
| 21. Yang, Haitao H and 9 more authors.. (2010) Structural insight into the mechanisms of enveloped virus tethering by tetherin.. Proceedings of the National Academy of Sciences of the United States of America, (26): [PMID:20940320] |
| 22. Weidner, Jessica M JM and 5 more authors.. (2010) Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms.. Journal of virology, [PMID:20943977] |
| 23. Kuhl, Björn D BD, Cheng, Vicky V, Wainberg, Mark A MA and Liang, Chen C.. (2011) Tetherin and its viral antagonists.. Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology, [PMID:21222046] |
| 24. Xu, Fengwen F and 7 more authors.. (2011) Tetherin inhibits prototypic foamy virus release.. Virology journal, (2): [PMID:21529378] |
| 25. Watanabe, Rie R, Leser, George P GP and Lamb, Robert A RA.. (2011) Influenza virus is not restricted by tetherin whereas influenza VLP production is restricted by tetherin.. Virology, (15): [PMID:21621240] |
| 26. Le Tortorec, Anna A, Willey, Suzanne S and Neil, Stuart J D SJ.. (2011) Antiviral inhibition of enveloped virus release by tetherin/BST-2: action and counteraction.. Viruses, [PMID:21994744] |
| 27. Gu, Gongping G, Zhao, Dejian D, Yin, Ziming Z and Liu, Ping P.. (2012) BST-2 binding with cellular MT1-MMP blocks cell growth and migration via decreasing MMP2 activity.. Journal of cellular biochemistry, [PMID:22065321] |
| 28. Arias, Juan F; Iwabu, Yukie and Tokunaga, Kenzo.. (2011) Structural Basis for the Antiviral Activity of BST-2/Tetherin and Its Viral Antagonism.. Frontiers in microbiology, [PMID:22180752] |
| 29. Sato, Kei K, Gee, Peter P and Koyanagi, Yoshio Y.. (2012) Vpu and BST2: Still Not There Yet?. Frontiers in microbiology, [PMID:22509177] |
| 30. Dafa-Berger, Avis A and 5 more authors.. (2012) Modulation of hepatitis C virus release by the interferon-induced protein BST-2/tetherin.. Virology, (5): [PMID:22520941] |
| 31. Hammonds, Jason; Wang, Jaang-Jiun and Spearman, Paul.. (2012) Restriction of Retroviral Replication by Tetherin/BST-2.. Molecular biology international, [PMID:22811908] |
| 32. Van Damme, Petra P and 15 more authors.. (2012) N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.. Proceedings of the National Academy of Sciences of the United States of America, (31): [PMID:22814378] |
| 33. Cocka, Luis J LJ and Bates, Paul P.. (2012) Identification of alternatively translated Tetherin isoforms with differing antiviral and signaling activities.. PLoS pathogens, [PMID:23028328] |
| 34. Bego, Mariana G MG and 5 more authors.. (2015) Vpu Exploits the Cross-Talk between BST2 and the ILT7 Receptor to Suppress Anti-HIV-1 Responses by Plasmacytoid Dendritic Cells.. PLoS pathogens, [PMID:26172439] |
| 35. Taylor, Justin K JK and 7 more authors.. (2015) Severe Acute Respiratory Syndrome Coronavirus ORF7a Inhibits Bone Marrow Stromal Antigen 2 Virion Tethering through a Novel Mechanism of Glycosylation Interference.. Journal of virology, [PMID:26378163] |
| 36. Thomas R Burkard,Melanie Planyavsky,Ines Kaupe,Florian P Breitwieser,Tilmann Bürckstümmer,Keiryn L Bennett,Giulio Superti-Furga,Jacques Colinge. (2011-01-29) Initial characterization of the human central proteome.. BMC systems biology, 5 (17-17). [PMID:21269460] |
