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Recombinant c-Maf Antibody

Recombinant

Validated

ExactAb™

Lot by Lot

Features and benefits

Short Overview:
Recombinant; Rabbit anti Human c-Maf Antibody; WB; Unconjugated
Species reactivity(Reacts with): Human,Mouse,Rat
Isotype: Rabbit IgG

Application:

Item Number

Ab096954

Grouped product items
SKU	Size	Availability	Price
Ab096954-10μl	10μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$69.90
Ab096954-50μl	50μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$199.90
Ab096954-100μl	100μl	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$289.90
Ab096954-1ml	1ml	Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding.	$2,299.90

Recombinant; Rabbit anti Human c-Maf Antibody; WB; Unconjugated

View related series

Click to view target information: MAF

Fluorescence dye Naphthyridine compounds peptide receptor Signaling Pathways

Basic Description

Product Name	Recombinant c-Maf Antibody
Synonyms	Avian musculoaponeurotic fibrosarcoma (MAF) protooncogene antibody \| Avian musculoaponeurotic fibrosarcoma (v maf)antibody \| c maf proto oncogene antibody \| cMaf antibody \| maf antibody \| MAF_HUMAN antibody \| MAF2 antibody \| MGC71685 antibody \| AS42 oncog
Specifications & Purity	ExactAb™, Validated, Recombinant, Lot by Lot
Host species	Rabbit
Specificity	MAF
Immunogen	A synthetic peptide derived from human c-Maf (AA 331-362)
Positive Control	WB: HeLa, Jurkat, Hep G2, A549, HUVEC, Raji, NIH/3T3 and C6 cell lysates.
Conjugation	Unconjugated
Grade	ExactAb™, Recombinant, Validated
Product Description	Rabbit anti Human c-Maf Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/2000 Protein Function Acts as a transcriptional activator or repressor. Involved in embryonic lens fiber cell development. Recruits the transcriptional coactivators CREBBP and/or EP300 to crystallin promoters leading to up-regulation of crystallin gene during lens fiber cell differentiation. Activates the expression of IL4 in T helper 2 (Th2) cells. Increases T cell susceptibility to apoptosis by interacting with MYB and decreasing BCL2 expression. Together with PAX6, transactivates strongly the glucagon gene promoter through the G1 element. Activates transcription of the CD13 proximal promoter in endothelial cells. Represses transcription of the CD13 promoter in early stages of myelopoiesis by affecting the ETS1 and MYB cooperative interaction. Involved in the initial chondrocyte terminal differentiation and the disappearance of hypertrophic chondrocytes during endochondral bone development. Binds to the sequence 5'-[GT]G[GC]N[GT]NCTCAGNN-3' in the L7 promoter. Binds to the T-MARE (Maf response element) sites of lens-specific alpha- and beta-crystallin gene promoters. Binds element G1 on the glucagon promoter. Binds an AT-rich region adjacent to the TGC motif (atypical Maf response element) in the CD13 proximal promoter in endothelial cells (By similarity). When overexpressed, represses anti-oxidant reponse element (ARE)-mediated transcription. Involved either as an oncogene or as a tumor suppressor, depending on the cell context. Binds to the ARE sites of detoxifying enzyme gene promoters. Post-translational Ubiquitinated, leading to its degradation by the proteasome. Ubiquitination is triggered by glucocorticoids. Phosphorylated by GSK3 and MAPK13 on serine and threonine residues (Probable). The phosphorylation status can serve to either stimulate or inhibit transcription.

Product Properties

Isotype	Rabbit IgG
Light Chain Type	Kappa
SDS-PAGE	150 kDa
Purification Method	Protein A purified
Form	Liquid
Concentration	Lot by Lot
Storage Temp	Store at -20°C,Avoid repeated freezing and thawing
Shipped In	Ice chest + Ice pads
Stability And Storage	Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant c-Maf Antibody (Ab096954) - Western Blot
All lanes: Recombinant c-Maf Antibody (Ab096954) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 42 kDa
Observed band size: 45 kDa
Exposure time: 32.9 s

Application

Dilution info

1/500-1/2000

Certificates

Certificate of Analysis(COA)

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Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot Number	Certificate Type	Date	Item
ZJ24F0708578	Certificate of Analysis	Jul 22, 2024	Ab096954
ZJ24F0708577	Certificate of Analysis	Jul 22, 2024	Ab096954

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