Recombinant CA153 Antibody - Primary antibody, for ELISA,CLIA,Detection antibody various applications, from Human, generated in Mouse, specific to CA153, IgG1

Features and benefits
  • Short Overview:

    Recombinant (25A3); Mouse anti Human CA153 Antibody; Detection antibody, ELISA, CLIA; Unconjugated

  • Application: ELISA,CLIA,Detection antibody
  • Species reactivity(Reacts with): Human
  • Isotype: IgG1
    Application:
  • CLIA
  • Detection Antibody
  • ELISA
Item Number
Ab116378
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab116378-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$39.90
Ab116378-50μg
50μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$117.90
Ab116378-100μg
100μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$147.90
Ab116378-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,107.90

Recombinant (25A3); Mouse anti Human CA153 Antibody; Detection antibody, ELISA, CLIA; Unconjugated

Basic Description

Product NameRecombinant CA153 Antibody - Primary antibody, for ELISA,CLIA,Detection antibody various applications, from Human, generated in Mouse, specific to CA153, IgG1
SynonymsADMCKD antibody; ADMCKD1 antibody; Breast carcinoma associated antigen DF3 antibody; Breast carcinoma-associated antigen DF3 antibody; CA 15-3 antibody; CA15 3 antibody; CA15 3 antigen antibody; CA15-3 antibody; CA15.3 antibody; Cancer antigen 15-3 antibo
Specifications & PurityExactAb™, Validated, Carrier Free, Azide Free, Recombinant, Lot by Lot
Host SpeciesMouse
Host speciesMouse
SpecificityCA153
ApplicationELISA,CLIA,Detection antibody
ImmunogenNative protein
EpitopeCore peptides (Class DF3)
ConjugationUnconjugated
GradeAzide Free, Carrier Free, ExactAb™, Recombinant, Validated
Product Description

Recombinant (25A3), Mouse anti Human CA153 Antibody could used as the detection antibody in ELISA, CLIA at 1.0 μg/mL.

Product Properties

Antibody TypePrimary antibody
ClonalityRecombinant
IsotypeIgG1
SDS-PAGE150kDa
Purification MethodProtein A or Protein G purified
Matched Pairs[Ab005519] Recombinant Cancer Antigen 153 (CA153) Antibody as capture antibody
SourceCHO supernatant
FormLiquid
ConcentrationLot by Lot
Storage TempStore at 2-8°C,Avoid repeated freezing and thawing
Shipped InWet ice
Stability And StorageStorage: 2-8℃ . Avoid repeated freeze/thaw cycles.

Associated Targets(Human)

MUC1 Tchem Mucin-1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
ELISA

1 μg/mL

CLIA

1 μg/mL

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
ZJ23F0500196Certificate of AnalysisMay 25, 2023 Ab116378
ZJ23F0500197Certificate of AnalysisMay 25, 2023 Ab116378
ZJ23F0500151Certificate of AnalysisMay 17, 2023 Ab116378
ZJ23F0500152Certificate of AnalysisMay 17, 2023 Ab116378

Related Documents

References

1. Tsarfaty, I I and 9 more authors..  (1990)  Isolation and characterization of an expressed hypervariable gene coding for a breast-cancer-associated antigen..  Gene,    (14):   [PMID:1688329]
2. Gendler, S J SJ and 8 more authors..  (1990)  Molecular cloning and expression of human tumor-associated polymorphic epithelial mucin..  The Journal of biological chemistry,    (5):   [PMID:1697589]
3. Hareuveni, M M and 9 more authors..  (1990)  A transcribed gene, containing a variable number of tandem repeats, codes for a human epithelial tumor antigen. cDNA cloning, expression of the transfected gene and over-expression in breast cancer tissue..  European journal of biochemistry,    (20):   [PMID:2112460]
4. Lancaster, C A CA and 5 more authors..  (1990)  Structure and expression of the human polymorphic epithelial mucin gene: an expressed VNTR unit..  Biochemical and biophysical research communications,    (31):   [PMID:2268309]
5. Ligtenberg, M J MJ, Vos, H L HL, Gennissen, A M AM and Hilkens, J J..  (1990)  Episialin, a carcinoma-associated mucin, is generated by a polymorphic gene encoding splice variants with alternative amino termini..  The Journal of biological chemistry,    (5):   [PMID:2318825]
6. Wreschner, D H DH and 9 more authors..  (1990)  Human epithelial tumor antigen cDNA sequences. Differential splicing may generate multiple protein forms..  European journal of biochemistry,    (20):   [PMID:2351132]
7. Lan, M S MS, Batra, S K SK, Qi, W N WN, Metzgar, R S RS and Hollingsworth, M A MA..  (1990)  Cloning and sequencing of a human pancreatic tumor mucin cDNA..  The Journal of biological chemistry,    (5):   [PMID:2394722]
8. Abe, M M, Siddiqui, J J and Kufe, D D..  (1989)  Sequence analysis of the 5' region of the human DF3 breast carcinoma-associated antigen gene..  Biochemical and biophysical research communications,    (15):   [PMID:2597151]
9. Gendler, S S, Taylor-Papadimitriou, J J, Duhig, T T, Rothbard, J J and Burchell, J J..  (1988)  A highly immunogenic region of a human polymorphic epithelial mucin expressed by carcinomas is made up of tandem repeats..  The Journal of biological chemistry,    (15):   [PMID:3417635]
10. Pandey, P P, Kharbanda, S S and Kufe, D D..  (1995)  Association of the DF3/MUC1 breast cancer antigen with Grb2 and the Sos/Ras exchange protein..  Cancer research,    (15):   [PMID:7664271]
11. Zrihan-Licht, S S and 7 more authors..  (1994)  Characterization and molecular cloning of a novel MUC1 protein, devoid of tandem repeats, expressed in human breast cancer tissue..  European journal of biochemistry,    (1):   [PMID:7925397]
12. Zrihan-Licht, S S, Baruch, A A, Elroy-Stein, O O, Keydar, I I and Wreschner, D H DH..  (1994)  Tyrosine phosphorylation of the MUC1 breast cancer membrane proteins. Cytokine receptor-like molecules..  FEBS letters,    (12):   [PMID:7988707]
13. Yu, C J CJ and 8 more authors..  ()  Mucin mRNA expression in lung adenocarcinoma cell lines and tissues..  Oncology,      [PMID:8604237]
14. Weiss, M M, Baruch, A A, Keydar, I I and Wreschner, D H DH..  (1996)  Preoperative diagnosis of thyroid papillary carcinoma by reverse transcriptase polymerase chain reaction of the MUC1 gene..  International journal of cancer,    (28):   [PMID:8608966]
15. Yamamoto, M M, Bharti, A A, Li, Y Y and Kufe, D D..  (1997)  Interaction of the DF3/MUC1 breast carcinoma-associated antigen and beta-catenin in cell adhesion..  The Journal of biological chemistry,    (9):   [PMID:9139698]
16. Oosterkamp, H M HM, Scheiner, L L, Stefanova, M C MC, Lloyd, K O KO and Finstad, C L CL..  (1997)  Comparison of MUC-1 mucin expression in epithelial and non-epithelial cancer cell lines and demonstration of a new short variant form (MUC-1/Z)..  International journal of cancer,    (3):   [PMID:9212228]
17. Müller, S S and 5 more authors..  (1997)  Localization of O-glycosylation sites on glycopeptide fragments from lactation-associated MUC1. All putative sites within the tandem repeat are glycosylation targets in vivo..  The Journal of biological chemistry,    (3):   [PMID:9312074]
18. Li, Y Y, Bharti, A A, Chen, D D, Gong, J J and Kufe, D D..  (1998)  Interaction of glycogen synthase kinase 3beta with the DF3/MUC1 carcinoma-associated antigen and beta-catenin..  Molecular and cellular biology,      [PMID:9819408]
19. Baruch, A A and 10 more authors..  (1999)  The breast cancer-associated MUC1 gene generates both a receptor and its cognate binding protein..  Cancer research,    (1):   [PMID:10197628]
20. Müller, S S and 5 more authors..  (1999)  High density O-glycosylation on tandem repeat peptide from secretory MUC1 of T47D breast cancer cells..  The Journal of biological chemistry,    (25):   [PMID:10373415]
21. Li, Y Y, Kuwahara, H H, Ren, J J, Wen, G G and Kufe, D D..  (2001)  The c-Src tyrosine kinase regulates signaling of the human DF3/MUC1 carcinoma-associated antigen with GSK3 beta and beta-catenin..  The Journal of biological chemistry,    (2):   [PMID:11152665]
22. Parry, S S and 5 more authors..  (2001)  Identification of MUC1 proteolytic cleavage sites in vivo..  Biochemical and biophysical research communications,    (11):   [PMID:11341784]
23. Engelmann, K K, Baldus, S E SE and Hanisch, F G FG..  (2001)  Identification and topology of variant sequences within individual repeat domains of the human epithelial tumor mucin MUC1..  The Journal of biological chemistry,    (27):   [PMID:11350974]
24. Ren, Jian J, Li, Yongqing Y and Kufe, Donald D..  (2002)  Protein kinase C delta regulates function of the DF3/MUC1 carcinoma antigen in beta-catenin signaling..  The Journal of biological chemistry,    (17):   [PMID:11877440]
25. Thathiah, Amantha A, Blobel, Carl P CP and Carson, Daniel D DD..  (2003)  Tumor necrosis factor-alpha converting enzyme/ADAM 17 mediates MUC1 shedding..  The Journal of biological chemistry,    (31):   [PMID:12441351]
26. Li, Yongqing Y and 7 more authors..  (2003)  Heregulin targets gamma-catenin to the nucleolus by a mechanism dependent on the DF3/MUC1 oncoprotein..  Molecular cancer research : MCR,      [PMID:12939402]
27. Huang, Lei L and 5 more authors..  ()  MUC1 cytoplasmic domain coactivates Wnt target gene transcription and confers transformation..  Cancer biology & therapy,      [PMID:14688481]
28. Kinlough, Carol L CL, Poland, Paul A PA, Bruns, James B JB, Harkleroad, Keri L KL and Hughey, Rebecca P RP..  (2004)  MUC1 membrane trafficking is modulated by multiple interactions..  The Journal of biological chemistry,    (17):   [PMID:15471854]
29. Mukherjee, P P, Tinder, T L TL, Basu, G D GD and Gendler, S J SJ..  (2005)  MUC1 (CD227) interacts with lck tyrosine kinase in Jurkat lymphoma cells and normal T cells..  Journal of leukocyte biology,      [PMID:15513966]
30. Levitin, Fiana F and 19 more authors..  (2005)  A novel protein derived from the MUC1 gene by alternative splicing and frameshifting..  The Journal of biological chemistry,    (18):   [PMID:15623537]
31. Wei, Xiaolong X, Xu, Hai H and Kufe, Donald D..  (2005)  Human MUC1 oncoprotein regulates p53-responsive gene transcription in the genotoxic stress response..  Cancer cell,      [PMID:15710329]
32. Zhang, Li-Xin LX, Li, Chun-Hai CH, Sun, Li-Ya LY, Wang, Miao M and Lu, Hao-Jun HJ..  (2003)  [Soluble expression of peptide containing MUC1/Y-specific epitope in Escherichia coli and preparation of the antibody]..  Sheng wu gong cheng xue bao = Chinese journal of biotechnology,      [PMID:15969018]
33. Engelmann, Katja K and 6 more authors..  (2005)  Transmembrane and secreted MUC1 probes show trafficking-dependent changes in O-glycan core profiles..  Glycobiology,      [PMID:15972891]
34. Levitin, Fiana F and 8 more authors..  (2005)  The MUC1 SEA module is a self-cleaving domain..  The Journal of biological chemistry,    (30):   [PMID:15987679]
35. Huang, Lei L and 5 more authors..  (2005)  MUC1 oncoprotein blocks glycogen synthase kinase 3beta-mediated phosphorylation and degradation of beta-catenin..  Cancer research,    (15):   [PMID:16288032]
36. Wei, Xiaolong X, Xu, Hai H and Kufe, Donald D..  (2006)  MUC1 oncoprotein stabilizes and activates estrogen receptor alpha..  Molecular cell,    (20):   [PMID:16427018]
37. Parry, Simon S and 6 more authors..  (2006)  N-Glycosylation of the MUC1 mucin in epithelial cells and secretions..  Glycobiology,      [PMID:16585136]
38. Gregory, S G SG and 178 more authors..  (2006)  The DNA sequence and biological annotation of human chromosome 1..  Nature,    (18):   [PMID:16710414]
39. Pochampalli, M R MR, el Bejjani, R M RM and Schroeder, J A JA..  (2007)  MUC1 is a novel regulator of ErbB1 receptor trafficking..  Oncogene,    (15):   [PMID:16983337]
40. Wei, Xiaolong X, Xu, Hai H and Kufe, Donald D..  (2007)  Human mucin 1 oncoprotein represses transcription of the p53 tumor suppressor gene..  Cancer research,    (15):   [PMID:17308127]
41. Lillehoj, Erik P EP, Lu, Wenju W, Kiser, Timothy T, Goldblum, Simeon E SE and Kim, K Chul KC..  (2007)  MUC1 inhibits cell proliferation by a beta-catenin-dependent mechanism..  Biochimica et biophysica acta,      [PMID:17524503]
42. Singh, Pankaj K PK and 7 more authors..  (2007)  Platelet-derived growth factor receptor beta-mediated phosphorylation of MUC1 enhances invasiveness in pancreatic adenocarcinoma cells..  Cancer research,    (1):   [PMID:17545600]
43. Duffy, Michael J MJ, Evoy, Denis D and McDermott, Enda W EW..  (2010)  CA 15-3: uses and limitation as a biomarker for breast cancer..  Clinica chimica acta; international journal of clinical chemistry,    (14):   [PMID:20816948]
44. Zhang, Lixin L, Vlad, Anda A, Milcarek, Christine C and Finn, Olivera J OJ..  (2013)  Human mucin MUC1 RNA undergoes different types of alternative splicing resulting in multiple isoforms..  Cancer immunology, immunotherapy : CII,      [PMID:22941036]
45. Zhou, Houjiang H and 6 more authors..  (2013)  Toward a comprehensive characterization of a human cancer cell phosphoproteome..  Journal of proteome research,    (4):   [PMID:23186163]
46. Kirby, Andrew A and 42 more authors..  (2013)  Mutations causing medullary cystic kidney disease type 1 lie in a large VNTR in MUC1 missed by massively parallel sequencing..  Nature genetics,      [PMID:23396133]
47. Li, Y Y and 7 more authors..  (2001)  The epidermal growth factor receptor regulates interaction of the human DF3/MUC1 carcinoma antigen with c-Src and beta-catenin..  The Journal of biological chemistry,    (21):   [PMID:11483589]

Solution Calculators