A synthetic peptide derived from human CCDC98 (AA 380-409).
Positive Control
WB: MCF7, HeLa, HEK293 and Jurkat cell lysates. IP: HeLa lysates.
Conjugation
Unconjugated
Grade
ExactAb™, KD Validation, Recombinant, Validated
Product Description
Rabbit anti Human CCDC98 Antibody, Recombinant, could be used for WB, IP and so on. Application: WB: 1/500-1/2000 IP: 1/50 Protein Function: Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the BRCA1-BARD1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as a central scaffold protein that assembles the various components of the BRCA1-A complex and mediates the recruitment of BRCA1.
Product Properties
Isotype
Rabbit IgG
Light Chain Type
kappa
SDS-PAGE
150 kDa
Purification Method
Protein A purified
Form
Liquid
Concentration
Lot by Lot
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
Images
Recombinant CCDC98 Antibody (Ab093417) - Western Blot All lanes: Recombinant CCDC98 Antibody (Ab093417) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 47 kDa Observed band size: 49 kDa Exposure time: 54.3 s
Recombinant CCDC98 Antibody (Ab093417) - IP Immunoprecipitate (IP) analysis using Recombinant CCDC98 Antibody (Ab093417) at 1/50 dilution (WB with Recombinant CCDC98 Antibody (Ab093417) at 1/6000 dilution).
Recombinant CCDC98 Antibody (Ab093417) - Western Blot All lanes use Recombinant CCDC98 Antibody (Ab093417) at 1/1000 dilution for 1 hour at room temperature.