| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab176339-10T (Trial Size) Apply for free trial size（?） Every year, as a valued customer, you have the exclusive opportunity to explore and enjoy three different trial products of your choice, absolutely free! | 10T | In stock | $93.90 | |
| Ab176339-25T | 25T | In stock | $139.90 | |
| Ab176339-100T | 100T | In stock | $299.90 |
Recombinant; CD30 Antibody (APC); Flow
| Product Name | Recombinant CD30 Antibody (APC) - Primary antibody, specific to TNFRSF8, Human IgG1 |
|---|---|
| Synonyms | CD 30 antibody | CD30 antibody | CD30 antigen antibody | CD30L receptor antibody | Cytokine receptor CD30 antibody | D1S166E antibody | KI 1 antibody | KI 1 antigenantibody | Ki-1 antigen antibody | KI1 antibody | Lymphocyte activation antigen CD30 antibo |
| Specifications & Purity | ExactAb™, Validated, Azide Free, Recombinant, 5μL/test |
| Host species | Human |
| Specificity | TNFRSF8 |
| Positive Control | Flow: Jurkat |
| Conjugation | APC |
| Grade | Azide Free, ExactAb™, Recombinant, Validated |
| Product Description | Application: |
| Isotype | Human IgG1 |
|---|---|
| Light Chain Type | kappa |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | 5μL/test |
| Storage Temp | Store at 2-8°C,Protected from light,Freeze prohibited |
| Shipped In | Wet ice |
| Stability And Storage | The antibody solution should be stored undiluted between 2°C and 8°C for one year. Do not freeze. Protect from light. |
Recombinant CD30 Antibody (APC) (Ab176339) - Flow Cytometry
Flow cytometry analysis of CD30 expression by Jurkat cells (red) compared to an isotype control (blue). Cells were stained with Recombinant CD30 Antibody (APC) (Ab176339) at 5μL/test for 1 hour at 4°C. Blue - Isotype control. Black - Unlabelled control, cells without incubation with primary antibody.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Application | Dilution info |
|---|---|
| Flow Cytometry |
5μl/test For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. "> 5μl/test For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood. |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0102320 | Certificate of Analysis | Jan 10, 2024 | Ab176339 |
| ZJ24F0102319 | Certificate of Analysis | Jan 10, 2024 | Ab176339 |
| ZJ24F0102318 | Certificate of Analysis | Jan 10, 2024 | Ab176339 |
| ZJ23R1200196 | Certificate of Analysis | Dec 21, 2023 | Ab176339 |
| 1. Reusch U, Burkhardt C, Fucek I, Le Gall F, Le Gall M, Hoffmann K, Knackmuss SH, Kiprijanov S, Little M, Zhukovsky EA. (2014) A novel tetravalent bispecific TandAb (CD30/CD16A) efficiently recruits NK cells for the lysis of CD30+ tumor cells.. MAbs, 6 (3): (728-39). [PMID:24670809] [10.1021/op500134e] |
| 2. Dürkop, H H and 5 more authors.. (1992) Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease.. Cell, (7): [PMID:1310894] |
| 3. Jung, W W and 6 more authors.. (1994) Opposite effects of the CD30 ligand are not due to CD30 mutations: results from cDNA cloning and sequence comparison of the CD30 antigen from different sources.. Molecular immunology, [PMID:7527901] |
| 4. Smith, C A CA and 9 more authors.. (1993) CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF.. Cell, (2): [PMID:8391931] |
| 5. Lee, S Y SY, Park, C G CG and Choi, Y Y.. (1996) T cell receptor-dependent cell death of T cell hybridomas mediated by the CD30 cytoplasmic domain in association with tumor necrosis factor receptor-associated factors.. The Journal of experimental medicine, (1): [PMID:8627180] |
| 6. Horie, R R and 9 more authors.. (1996) A variant CD30 protein lacking extracellular and transmembrane domains is induced in HL-60 by tetradecanoylphorbol acetate and is expressed in alveolar macrophages.. Blood, (1): [PMID:8839832] |
| 7. Aizawa, S S and 9 more authors.. (1997) Tumor necrosis factor receptor-associated factor (TRAF) 5 and TRAF2 are involved in CD30-mediated NFkappaB activation.. The Journal of biological chemistry, (24): [PMID:8999898] |
| 8. Boucher, L M LM, Marengère, L E LE, Lu, Y Y, Thukral, S S and Mak, T W TW.. (1997) Binding sites of cytoplasmic effectors TRAF1, 2, and 3 on CD30 and other members of the TNF receptor superfamily.. Biochemical and biophysical research communications, (28): [PMID:9168896] |
| 9. Mizushima, S S and 8 more authors.. (1998) Cloning and characterization of a cDNA encoding the human homolog of tumor necrosis factor receptor-associated factor 5 (TRAF5).. Gene, (30): [PMID:9511754] |
| 10. Francisco, Joseph A JA and 14 more authors.. (2003) cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity.. Blood, (15): [PMID:12714494] |
