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Recombinant CD30 Antibody (PE) - Primary antibody, specific to TNFRSF8, Human IgG1

  • Azide Free
  • ExactAb™
  • Recombinant
  • Validated
  • 5μL/test
Features and benefits
  • Short Overview:

    Recombinant; CD30 Antibody (PE); Flow

  • Species reactivity(Reacts with): Cynomolgus monkey,Human
  • Isotype: Human IgG1
    Application:
  • Flow Cytometry
Item Number
Ab176338
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab176338-10T (Trial Size)
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10T
In stock
$66.90
Ab176338-25T
25T
In stock
$99.90
Ab176338-100T
100T
In stock
$239.90

Recombinant; CD30 Antibody (PE); Flow

Basic Description

Product NameRecombinant CD30 Antibody (PE) - Primary antibody, specific to TNFRSF8, Human IgG1
SynonymsCD 30 antibody|CD30 antibody|CD30 antigen antibody|CD30L receptor antibody|Cytokine receptor CD30 antibody|D1S166E antibody|KI 1 antibody|KI 1 antigenantibody|Ki-1 antigen antibody|KI1 antibody|Lymphocyte activation antigen CD30 antibody|TNFRSF 8 antibody
Specifications & PurityExactAb™, Validated, Azide Free, Recombinant, 5μL/test
SpecificityTNFRSF8
Positive ControlFlow: Jurkat
ConjugationPE
GradeAzide Free, ExactAb™, Recombinant, Validated
Product Description

Application:
Flow: 5μL/test
For flow cytometric staining, the suggested use of this reagent is 5 µL per million cells in 100 µL staining volume or 5 µL per 100 µL of whole blood.

Product Properties

IsotypeHuman IgG1
Light Chain Typekappa
Purification MethodProtein A purified
FormLiquid
Concentration5μL/test
Storage TempStore at 2-8°C,Protected from light,Freeze prohibited
Shipped InWet ice
Stability And StorageThe antibody solution should be stored undiluted between 2°C and 8°C for one year. Do not freeze. Protect from light.

Images

Recombinant CD30 Antibody (PE) (Ab176338) - Flow Cytometry
Flow cytometry analysis of CD30 expression by Jurkat cells (red) compared to an isotype control (blue). Cells were stained with Recombinant CD30 Antibody (PE) (Ab176338) at 5μL/test for 1 hour at 4°C. Blue - Isotype control. Black - Unlabelled control, cells without incubation with primary antibody.

Associated Targets

TNFRSF8 Tclin Tumor necrosis factor receptor superfamily member 8 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
Flow

5μl/test

Certificates

Certificate of Analysis(COA)

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4 results found

Lot NumberCertificate TypeDateItem
ZJ24F0102317Certificate of AnalysisJan 10, 2024 Ab176338
ZJ24F0102316Certificate of AnalysisJan 10, 2024 Ab176338
ZJ24F0102315Certificate of AnalysisJan 10, 2024 Ab176338
ZJ23R1200195Certificate of AnalysisDec 21, 2023 Ab176338

Related Documents

References

1. Reusch U, Burkhardt C, Fucek I, Le Gall F, Le Gall M, Hoffmann K, Knackmuss SH, Kiprijanov S, Little M, Zhukovsky EA.  (2014)  A novel tetravalent bispecific TandAb (CD30/CD16A) efficiently recruits NK cells for the lysis of CD30+ tumor cells..  MAbs,  (3): (728-39).  [PMID:24670809]
2. Dürkop, H H and 5 more authors..  (1992)  Molecular cloning and expression of a new member of the nerve growth factor receptor family that is characteristic for Hodgkin's disease..  Cell,    (7):   [PMID:1310894]
3. Jung, W W and 6 more authors..  (1994)  Opposite effects of the CD30 ligand are not due to CD30 mutations: results from cDNA cloning and sequence comparison of the CD30 antigen from different sources..  Molecular immunology,      [PMID:7527901]
4. Smith, C A CA and 9 more authors..  (1993)  CD30 antigen, a marker for Hodgkin's lymphoma, is a receptor whose ligand defines an emerging family of cytokines with homology to TNF..  Cell,    (2):   [PMID:8391931]
5. Lee, S Y SY, Park, C G CG and Choi, Y Y..  (1996)  T cell receptor-dependent cell death of T cell hybridomas mediated by the CD30 cytoplasmic domain in association with tumor necrosis factor receptor-associated factors..  The Journal of experimental medicine,    (1):   [PMID:8627180]
6. Horie, R R and 9 more authors..  (1996)  A variant CD30 protein lacking extracellular and transmembrane domains is induced in HL-60 by tetradecanoylphorbol acetate and is expressed in alveolar macrophages..  Blood,    (1):   [PMID:8839832]
7. Aizawa, S S and 9 more authors..  (1997)  Tumor necrosis factor receptor-associated factor (TRAF) 5 and TRAF2 are involved in CD30-mediated NFkappaB activation..  The Journal of biological chemistry,    (24):   [PMID:8999898]
8. Boucher, L M LM, Marengère, L E LE, Lu, Y Y, Thukral, S S and Mak, T W TW..  (1997)  Binding sites of cytoplasmic effectors TRAF1, 2, and 3 on CD30 and other members of the TNF receptor superfamily..  Biochemical and biophysical research communications,    (28):   [PMID:9168896]
9. Mizushima, S S and 8 more authors..  (1998)  Cloning and characterization of a cDNA encoding the human homolog of tumor necrosis factor receptor-associated factor 5 (TRAF5)..  Gene,    (30):   [PMID:9511754]
10. Francisco, Joseph A JA and 14 more authors..  (2003)  cAC10-vcMMAE, an anti-CD30-monomethyl auristatin E conjugate with potent and selective antitumor activity..  Blood,    (15):   [PMID:12714494]

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