Recombinant CD79b Antibody - Primary antibody, specific to CD79B, Rabbit IgG

    Application:
  • WB
Features and benefits
  • Host species: Rabbit
  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
Item Number
Ab095331
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab095331-10μl
10μl
In stock
$66.90
Ab095331-50μl
50μl
In stock
$199.90
Ab095331-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab095331-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,399.90

Recombinant; Rabbit anti Human CD79b Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant CD79b Antibody - Primary antibody, specific to CD79B, Rabbit IgG
SynonymsAGM6 antibody | B cell antigen receptor complex associated protein beta chain antibody | B cell specific glycoprotein B29 antibody | B-cell antigen receptor complex-associated protein beta chain antibody | B-cell-specific glycoprotein B29 antibody | B29 a
Specifications & PurityExactAb™, Validated, Recombinant, 0.27 mg/mL
Host speciesRabbit
SpecificityCD79B
ImmunogenA synthetic peptide derived from human CD79b (AA 190-229)
Positive ControlWB: Mouse spleen, Ramos and Raji lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human CD79b Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500 - 1/1000
Protein Function
Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
Post-translational
Phosphorylated on tyrosine upon B-cell activation.

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration0.27 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant CD79b Antibody (Ab095331) - Western Blot
All lanes: Recombinant CD79b Antibody (Ab095331) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 26 kDa
Observed band size: 15, 36 kDa
Exposure time: 31.2 s

Associated Targets(Human)

CD79B Tclin B-cell antigen receptor complex-associated protein beta chain (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Application

ApplicationDilution info
WB1/500-1/1000

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1/500-1/1000

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0505476Certificate of AnalysisMay 13, 2024 Ab095331
ZJ24F0505475Certificate of AnalysisMay 13, 2024 Ab095331

Related Documents

References

1. Müller, B B, Cooper, L L and Terhorst, C C..  (1992)  Cloning and sequencing of the cDNA encoding the human homologue of the murine immunoglobulin-associated protein B29..  European journal of immunology,      [PMID:1534761]
2. Vasile, S S, Coligan, J E JE, Yoshida, M M and Seon, B K BK..  (1994)  Isolation and chemical characterization of the human B29 and mb-1 proteins of the B cell antigen receptor complex..  Molecular immunology,      [PMID:7514267]
3. Hashimoto, S S, Chiorazzi, N N and Gregersen, P K PK..  (1995)  Alternative splicing of CD79a (Ig-alpha/mb-1) and CD79b (Ig-beta/B29) RNA transcripts in human B cells..  Molecular immunology,      [PMID:7643857]
4. Hashimoto, S S, Chiorazzi, N N and Gregersen, P K PK..  (1994)  The complete sequence of the human CD79b (Ig beta/B29) gene: identification of a conserved exon/intron organization, immunoglobulin-like regulatory regions, and allelic polymorphism..  Immunogenetics,      [PMID:7913081]
5. Hashimoto, S S, Gregersen, P K PK and Chiorazzi, N N..  (1993)  The human Ig-beta cDNA sequence, a homologue of murine B29, is identical in B cell and plasma cell lines producing all the human Ig isotypes..  Journal of immunology (Baltimore, Md. : 1950),    (15):   [PMID:8419481]
6. Wood, W J WJ and 6 more authors..  (1993)  Isolation and chromosomal mapping of the human immunoglobulin-associated B29 gene (IGB)..  Genomics,      [PMID:8486355]
7. Dobbs, A Kerry and 5 more authors..  (2007)  Cutting edge: a hypomorphic mutation in Igbeta (CD79b) in a patient with immunodeficiency and a leaky defect in B cell development..  Journal of immunology (Baltimore, Md. : 1950),    (15):   [PMID:17675462]
8. Thomas R Burkard,Melanie Planyavsky,Ines Kaupe,Florian P Breitwieser,Tilmann Bürckstümmer,Keiryn L Bennett,Giulio Superti-Furga,Jacques Colinge.  (2011-01-29)  Initial characterization of the human central proteome..  BMC systems biology,  (17-17).  [PMID:21269460]

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