Recombinant CEACAM5 Antibody - Primary antibody, for ELISA,CLIA,Capture antibody various applications, from Human, generated in Mouse, specific to CEACAM5, IgG1

    Application:
  • Capture Antibody
  • CLIA
  • ELISA
Features and benefits
  • Host species: Mouse
  • Species reactivity(Reacts with): Human
  • Isotype: Mouse IgG1
  • Clone Number: 37C4
  • Conjugation: Unconjugated
Item Number
Ab095938
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab095938-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$19.90
Ab095938-50μg
50μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$57.90
Ab095938-100μg
100μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$87.90
Ab095938-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$507.90

Recombinant (37C4); Mouse anti Human CEACAM5 Antibody; Capture antibody, ELISA, CLIA; Unconjugated

Basic Description

Product NameRecombinant CEACAM5 Antibody - Primary antibody, for ELISA,CLIA,Capture antibody various applications, from Human, generated in Mouse, specific to CEACAM5, IgG1
SynonymsAnti-CEACAM5 Antibody | Recombinant CEACAM5 antibody | Carcinoembryonic antigen antibody | Carcinoembryonic antigen-related cell adhesion molecule 5 antibody | CD66e antibody | CEA antibody | Ceacam5 antibody | CEAM5_HUMAN antibody | DKFZp781M2392 antibod
Specifications & PurityExactAb™, Validated, Carrier Free, Azide Free, Recombinant, Lot by Lot
Host SpeciesMouse
Host speciesMouse
SpecificityCEACAM5
ApplicationELISA,CLIA,Capture antibody
ImmunogenNative protein
ConjugationUnconjugated
GradeAzide Free, Carrier Free, ExactAb™, Recombinant, Validated
Product Description

Recombinant (37C4), Mouse anti Human CEACAM5 Antibody could be as capture antibody in ELISA, CLIA at 1.0µg/mL.

Function
Cell surface glycoprotein that plays a role in cell adhesion and in intracellular signaling. Receptor for E.coli Dr adhesins.

Product Properties

Antibody TypePrimary antibody
ClonalityRecombinant
IsotypeIgG1
SDS-PAGE150KDa
Purification MethodProtein A purified
Matched Pairs[ Ab007319] Recombinant CEACAM5 antibody
SourceCHO supernatant
FormLiquid
ConcentrationLot by Lot
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStorage: -20℃ for long term storage. Avoid repeated freeze / thaw cycles.

Images

Relevance of detection results between aladdin Antibody Pair (Ab095938 & Ab007319) and Roche in CLIA

· Capture antibody: Recombinant CEACAM5 Antibody (Ab095938) at 1.0 μg/mL.

· Detection antibody: CEACAM5 Mouse mAb (Ab007319) at 1.0 μg/mL.

· Linear Range: 0.2-1000 ng/mL, R² ≥ 0.96.

Associated Targets(Human)

CEACAM5 Tbio Carcinoembryonic antigen-related cell adhesion molecule 5 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Application

ApplicationDilution info
ELISA

1 μg/mL

CLIA

1 μg/mL

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

4 results found

Lot NumberCertificate TypeDateItem
ZJ23F0500185Certificate of AnalysisMay 25, 2023 Ab095938
ZJ23F0500184Certificate of AnalysisMay 25, 2023 Ab095938
ZJ23F0500145Certificate of AnalysisMay 17, 2023 Ab095938
ZJ23F0500144Certificate of AnalysisMay 17, 2023 Ab095938

Related Documents

References

1. Hefta, L J LJ and 5 more authors..  (1990)  Expression of complementary DNA and genomic clones for carcinoembryonic antigen and nonspecific cross-reacting antigen in Chinese hamster ovary and mouse fibroblast cells and characterization of the membrane-expressed products..  Cancer research,    (15):   [PMID:2317824]
2. Schrewe, H H and 8 more authors..  (1990)  Cloning of the complete gene for carcinoembryonic antigen: analysis of its promoter indicates a region conveying cell type-specific expression..  Molecular and cellular biology,      [PMID:2342461]
3. Oikawa, S S and 5 more authors..  (1989)  Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: homophilic and heterophilic adhesion..  Biochemical and biophysical research communications,    (16):   [PMID:2803308]
4. Zimmermann, W W, Ortlieb, B B, Friedrich, R R and von Kleist, S S..  (1987)  Isolation and characterization of cDNA clones encoding the human carcinoembryonic antigen reveal a highly conserved repeating structure..  Proceedings of the National Academy of Sciences of the United States of America,      [PMID:3033671]
5. Barnett, T T, Goebel, S J SJ, Nothdurft, M A MA and Elting, J J JJ..  (1988)  Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains..  Genomics,      [PMID:3220478]
6. Beauchemin, N N, Benchimol, S S, Cournoyer, D D, Fuks, A A and Stanners, C P CP..  (1987)  Isolation and characterization of full-length functional cDNA clones for human carcinoembryonic antigen..  Molecular and cellular biology,      [PMID:3670312]
7. Oikawa, S S, Nakazato, H H and Kosaki, G G..  (1987)  Primary structure of human carcinoembryonic antigen (CEA) deduced from cDNA sequence..  Biochemical and biophysical research communications,    (30):   [PMID:3814146]
8. Frängsmyr, L L, Baranov, V V and Hammarström, S S..  ()  Four carcinoembryonic antigen subfamily members, CEA, NCA, BGP and CGM2, selectively expressed in the normal human colonic epithelium, are integral components of the fuzzy coat..  Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine,      [PMID:10436421]
9. Boehm, M K MK and Perkins, S J SJ..  (2000)  Structural models for carcinoembryonic antigen and its complex with the single-chain Fv antibody molecule MFE23..  FEBS letters,    (9):   [PMID:10854848]
10. Taheri, M M and 5 more authors..  (2000)  Self recognition in the Ig superfamily. Identification of precise subdomains in carcinoembryonic antigen required for intercellular adhesion..  The Journal of biological chemistry,    (1):   [PMID:10864933]
11. Ordoñez, C C, Screaton, R A RA, Ilantzis, C C and Stanners, C P CP..  (2000)  Human carcinoembryonic antigen functions as a general inhibitor of anoikis..  Cancer research,    (1):   [PMID:10910050]
12. Grimwood, Jane J and 97 more authors..  (2004)  The DNA sequence and biology of human chromosome 19..  Nature,    (1):   [PMID:15057824]
13. Ramachandran, Prasanna P and 5 more authors..  (2006)  Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry..  Journal of proteome research,      [PMID:16740002]
14. Korotkova, Natalia N and 9 more authors..  (2008)  Binding of Dr adhesins of Escherichia coli to carcinoembryonic antigen triggers receptor dissociation..  Molecular microbiology,      [PMID:18086185]
15. Govindan, Serengulam V SV, Cardillo, Thomas M TM, Moon, Sung-Ju SJ, Hansen, Hans J HJ and Goldenberg, David M DM..  (2009)  CEACAM5-targeted therapy of human colonic and pancreatic cancer xenografts with potent labetuzumab-SN-38 immunoconjugates..  Clinical cancer research : an official journal of the American Association for Cancer Research,    (1):   [PMID:19789330]
16. Bonsor, Daniel A DA, Günther, Sebastian S, Beadenkopf, Robert R, Beckett, Dorothy D and Sundberg, Eric J EJ..  (2015)  Diverse oligomeric states of CEACAM IgV domains..  Proceedings of the National Academy of Sciences of the United States of America,    (3):   [PMID:26483485]

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