| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab096045-10μl | 10μl | In stock | $86.90 | |
| Ab096045-50μl | 50μl | In stock | $259.90 | |
| Ab096045-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $369.90 | |
| Ab096045-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,399.90 |
Recombinant; Rabbit anti human CENPC antibody; WB; Unconjugated
| Product Name | Recombinant CENPC antibody - Primary antibody, specific to CENPC, Rabbit IgG |
|---|---|
| Synonyms | CENP-C1 | MIF2 | hcp-4 | CENPC | CENP-C 1 antibody | CENP-C antibody | CENPC_HUMAN antibody | CENPC1 antibody | Centromere autoantigen C antibody | Centromere autoantigen C1 antibody | Centromere protein C 1 antibody | Centromere protein C antibody | hcp- |
| Specifications & Purity | ExactAb™, Validated, Recombinant, 2.0 mg/mL |
| Host species | Rabbit |
| Specificity | CENPC |
| Immunogen | A synthetic peptide derived from human CENPC (AA 400-530) |
| Positive Control | WB: HeLa and C6 cell lysates. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description |
Rabbit anti Human CENPC Antibody, Recombinant, could be used for WB and so on. |
| Isotype | Rabbit IgG |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | 2.0 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Recombinant CENPC antibody (Ab096045) - Western Blot
All lanes: Recombinant CENPC antibody (Ab096045) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 107 kDa
Observed band size: 98 kDa
Exposure time: 12.2 s
Recombinant CENPC antibody (Ab096045) - Western Blot
All lanes: Recombinant CENPC antibody (Ab096045) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 107 kDa
Observed band size: 98 kDa
Exposure time: 30.0 s
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/500-1/1000"> 1/500-1/1000 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0505387 | Certificate of Analysis | May 11, 2024 | Ab096045 |
| ZJ24F0505386 | Certificate of Analysis | May 11, 2024 | Ab096045 |
| 1. Saitoh, H H and 6 more authors.. (1992) CENP-C, an autoantigen in scleroderma, is a component of the human inner kinetochore plate.. Cell, (10): [PMID:1339310] |
| 2. Pluta, A F AF, Earnshaw, W C WC and Goldberg, I G IG.. (1998) Interphase-specific association of intrinsic centromere protein CENP-C with HDaxx, a death domain-binding protein implicated in Fas-mediated cell death.. Journal of cell science, (30): [PMID:9645950] |
| 3. Hillier, Ladeana W LW and 121 more authors.. (2005) Generation and annotation of the DNA sequences of human chromosomes 2 and 4.. Nature, (7): [PMID:15815621] |
| 4. Foltz, Daniel R DR and 5 more authors.. (2006) The human CENP-A centromeric nucleosome-associated complex.. Nature cell biology, [PMID:16622419] |
| 5. Izuta, Hiroshi H and 10 more authors.. (2006) Comprehensive analysis of the ICEN (Interphase Centromere Complex) components enriched in the CENP-A chromatin of human cells.. Genes to cells : devoted to molecular & cellular mechanisms, [PMID:16716197] |
| 6. Alonso, Alicia A and 8 more authors.. (2007) Co-localization of CENP-C and CENP-H to discontinuous domains of CENP-A chromatin at human neocentromeres.. Genome biology, [PMID:17651496] |
| 7. Dephoure, Noah N and 6 more authors.. (2008) A quantitative atlas of mitotic phosphorylation.. Proceedings of the National Academy of Sciences of the United States of America, (5): [PMID:18669648] |
| 8. Gopalakrishnan, Suhasni S, Sullivan, Beth A BA, Trazzi, Stefania S, Della Valle, Giuliano G and Robertson, Keith D KD.. (2009) DNMT3B interacts with constitutive centromere protein CENP-C to modulate DNA methylation and the histone code at centromeric regions.. Human molecular genetics, (1): [PMID:19482874] |
| 9. Trazzi, Stefania S and 6 more authors.. (2009) The C-terminal domain of CENP-C displays multiple and critical functions for mammalian centromere formation.. PloS one, (8): [PMID:19503796] |
| 10. Mayya, Viveka V and 7 more authors.. (2009) Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.. Science signaling, (18): [PMID:19690332] |
| 11. Rigbolt, Kristoffer T G KT and 9 more authors.. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.. Science signaling, (15): [PMID:21406692] |
| 12. Gascoigne, Karen E KE and 5 more authors.. (2011) Induced ectopic kinetochore assembly bypasses the requirement for CENP-A nucleosomes.. Cell, (29): [PMID:21529714] |
| 13. Zhou, Houjiang H and 6 more authors.. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome.. Journal of proteome research, (4): [PMID:23186163] |
| 14. Dornblut, Carsten C and 11 more authors.. (2014) A CENP-S/X complex assembles at the centromere in S and G2 phases of the human cell cycle.. Open biology, (12): [PMID:24522885] |
| 15. Xiao, Zhenyu Z and 5 more authors.. (2015) System-wide Analysis of SUMOylation Dynamics in Response to Replication Stress Reveals Novel Small Ubiquitin-like Modified Target Proteins and Acceptor Lysines Relevant for Genome Stability.. Molecular & cellular proteomics : MCP, [PMID:25755297] |
| 16. Roulland, Yohan Y and 19 more authors.. (2016) The Flexible Ends of CENP-A Nucleosome Are Required for Mitotic Fidelity.. Molecular cell, (18): [PMID:27499292] |
