Recombinant CHMP2B Antibody - Primary antibody, specific to CHMP2B, Rabbit IgG

    Application:
  • WB
Features and benefits
  • Host species: Rabbit
  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
Item Number
Ab096362
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab096362-10μl
10μl
In stock
$66.90
Ab096362-50μl
50μl
In stock
$199.90
Ab096362-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab096362-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,499.90

Recombinant; Rabbit anti Human CHMP2B Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant CHMP2B Antibody - Primary antibody, specific to CHMP2B, Rabbit IgG
SynonymsALS17 antibody | Charged multivesicular body protein 2b antibody | CHM2B_HUMAN antibody | CHMP family, member 2B antibody | CHMP2.5 antibody | CHMP2b antibody | Chromatin modifying protein 2b antibody | Chromatin-modifying protein 2b antibody | DMT1 antib
Specifications & PurityExactAb™, Validated, Recombinant, 0.4 mg/mL
Host speciesRabbit
SpecificityCHMP2B
ImmunogenA synthetic peptide derived from human CHMP2B (AA 171-213)
Positive ControlWB: A431, HeLa, MCF7, A549, HEK293, NIH/3T3 and C6 cell lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human CHMP2B Antibody, Recombinant, could be used for WB and so on.
Application
WB: 1/500-1/1000
Protein Function
Probable core component of the endosomal sorting required for transport complex III (ESCRT-III) which is involved in multivesicular bodies (MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles (ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O, -I,-II and -III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis and the budding of enveloped viruses (HIV-1 and other lentiviruses). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4.

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration0.4 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant CHMP2B Antibody (Ab096362) - Western Blot
All lanes: Recombinant CHMP2B Antibody (Ab096362) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 24 kDa
Observed band size: 30 kDa
Exposure time: 1.1 s


Associated Targets(Human)

CHMP2B Tbio Charged multivesicular body protein 2b (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB1/500-1/1000

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1/500-1/1000

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberChartCertificate TypeDateItem
ZJ24F0505420Certificate of AnalysisMay 11, 2024 Ab096362
ZJ24F0505419Certificate of AnalysisMay 11, 2024 Ab096362

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