A synthetic peptide derived from human CRTC3 (AA 606-619)
Positive Control
WB: K562, HeLa, HEK293, Jurkat, U-2 OS and C6 cell lysates. ICC/IF: HeLa cell
Conjugation
Unconjugated
Grade
ExactAb™, Recombinant, Validated
Product Description
Rabbit anti Human CRTC3 Antibody, Recombinant, could be used for WB, ICC, IF and so on. Application: WB: 1/500-1/1000 ICC/IF: 1/50-1/200 Protein Function Transcriptional coactivator for CREB1 which activates transcription through both consensus and variant cAMP response element (CRE) sites. Acts as a coactivator, in the SIK/TORC signaling pathway, being active when dephosphorylated and acts independently of CREB1 'Ser-133' phosphorylation. Enhances the interaction of CREB1 with TAF4. Regulates the expression of specific CREB-activated genes such as the steroidogenic gene, StAR. Potent coactivator of PPARGC1A and inducer of mitochondrial biogenesis in muscle cells. Also coactivator for TAX activation of the human T-cell leukemia virus type 1 (HTLV-1) long terminal repeats (LTR).
Product Properties
Isotype
Rabbit IgG
Purification Method
Antigen affinity purified
Form
Liquid
Concentration
1.0 mg/mL
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
Images
Recombinant CRTC3 Antibody (Ab097855) - Western Blot All lanes: Recombinant CRTC3 Antibody (Ab097855) at 1/1000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 67 kDa Observed band size: 72 kDa Exposure time: 41.2 s
Recombinant CRTC3 Antibody (Ab097855) - IF/ICC Immunocytochemistry analysis of CRTC3 (green) in HeLa using Recombinant CRTC3 Antibody (Ab097855), and cells were counterstained with DAPI (blue).