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Recombinant DKK1 Antibody - Primary antibody, specific to DKK1, Rabbit IgG

  • ExactAb™
  • Recombinant
  • Validated
  • 1.2 mg/mL
Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human DKK1 Antibody; WB, IHC; Unconjugated

  • Species reactivity(Reacts with): Human,Rat
  • Isotype: Rabbit IgG
    Application:
  • IHC
  • WB
Item Number
Ab099940
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab099940-10μl
10μl
In stock
$66.90
Ab099940-50μl
50μl
In stock
$189.90
Ab099940-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab099940-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,599.90

Recombinant; Rabbit anti Human DKK1 Antibody; WB, IHC; Unconjugated

View related series
Accession#:O94907 DKK1 Gene ID:22943

Basic Description

Product NameRecombinant DKK1 Antibody - Primary antibody, specific to DKK1, Rabbit IgG
Synonymsdickkopf (Xenopus laevis) homolog 1; dickkopf homolog 1 (Xenopus laevis); dickkopf related protein-1; Dickkopf-1; dickkopf-related protein 1; Dkk1; Dkk-1; hDkk-1; SKdickkopf-1 like; Dickkopf 1 antibody; Dickkopf 1 homolog antibody; Dickkopf 1 like antibod
Specifications & PurityExactAb™, Validated, Recombinant, 1.2 mg/mL
Host speciesRabbit
SpecificityDKK1
ImmunogenA synthetic peptide derived from human DKK1 (AA 204-266).
Positive ControlWB: HeLa, MOLT-4, HEK293 and MCF7 cell lysates. IHC: Human placenta tissue.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human DKK1 Antibody, Recombinant, could be used for WB, IHC and so on.
Application:
WB: 1/500-1/1000
IHC: 1/50-1/100
Protein Function:
Antagonizes canonical Wnt signaling by inhibiting LRP5/6 interaction with Wnt and by forming a ternary complex with the transmembrane protein KREMEN that promotes internalization of LRP5/6. DKKs play an important role in vertebrate development, where they locally inhibit Wnt regulated processes such as antero-posterior axial patterning, limb development, somitogenesis and eye formation. In the adult, Dkks are implicated in bone formation and bone disease, cancer and Alzheimer disease.

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration1.2 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant DKK1 Antibody (Ab099940) - Western Blot
All lanes: Recombinant DKK1 Antibody (Ab099940) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 29 kDa
Observed band size: 37, 41, 50 kDa
Exposure time: 24.9 s

Recombinant DKK1 Antibody (Ab099940) - IHC
Immunohistochemistry analysis of paraffin-embedded Human placenta using Recombinant DKK1 Antibody (Ab099940). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Associated Targets

DKK1 Tchem Dickkopf-related protein 1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

1/500-1/1000

IHC

1/50 - 1/100

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0303272Certificate of AnalysisMar 14, 2024 Ab099940
ZJ24F0303271Certificate of AnalysisMar 14, 2024 Ab099940

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