Recombinant DOK1 Antibody - Primary antibody, specific to DOK1, Rabbit IgG

    Application:
  • WB
Features and benefits
  • Host species: Rabbit
  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
Item Number
Ab100293
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab100293-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$69.90
Ab100293-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$199.90
Ab100293-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab100293-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,399.90

Recombinant; Rabbit anti Human DOK1 Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant DOK1 Antibody - Primary antibody, specific to DOK1, Rabbit IgG
SynonymsDocking protein 1 62kD antibody | Docking protein 1 antibody | DOK 1 antibody | DOK1 antibody | DOK1_HUMAN antibody | Downstream of tyrosine kinase 1 antibody | p62(dok) antibody | P62DOK antibody | pp62 antibody | DOK1 | pp62 | P62DOK | Anti-DOK1 antibod
Specifications & PurityExactAb™, Validated, Recombinant, 0.5 mg/mL
Host speciesRabbit
SpecificityDOK1
ImmunogenA synthetic peptide derived from human DOK1 (AA 430-481)
Positive ControlWB: K562, Jurkat, NIH/3T3 and C6 cell lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human DOK1 Antibody, Recombinant, could be used for WB and so on.

Application:

WB: 1/500 - 1/1000

Protein Function

DOK proteins are enzymatically inert adaptor or scaffolding proteins. They provide a docking platform for the assembly of multimolecular signaling complexes. DOK1 appears to be a negative regulator of the insulin signaling pathway. Modulates integrin activation by competing with talin for the same binding site on ITGB3. 

Post-translational

Constitutively tyrosine-phosphorylated.
Phosphorylated on tyrosine residues by the insulin receptor kinase. Results in the negative regulation of the insulin signaling pathway.

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration0.5 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant DOK1 Antibody (Ab100293) - Western Blot
All lanes: Recombinant DOK1 Antibody (Ab100293) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 52 kDa
Observed band size: 44, 58 kDa
Exposure time: 21.5 s 

Recombinant DOK1 Antibody (Ab100293) - Western Blot
All lanes: Recombinant DOK1 Antibody (Ab100293) at 1/1000 dilution
Samples: Lysates at 10 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 52 kDa
Observed band size: 44, 58 kDa
Exposure time: 3.0 s 

Associated Targets(Human)

DOK1 Tbio Docking protein 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB 1/500-1/1000

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1/500-1/1000

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0809176Certificate of AnalysisAug 05, 2024 Ab100293
ZJ24F0809175Certificate of AnalysisAug 05, 2024 Ab100293

Related Documents

Solution Calculators