Recombinant Egr1 Antibody - Primary antibody, specific to Egr1, Rabbit IgG
Synonyms
AT225 | NGFI-A | AT225Transcription factor ETR103 | early growth response 1 | early growth response protein 1 | EGR1 | EGR-1 | G0S30 | KROX24 | KROX-24 | Nerve growth factor-induced protein A | NGFIA | NGFI-ATranscription factor Zif268 | TIS8 | ZIF-268 |
Specifications & Purity
ExactAb™, Validated, Recombinant, 1.11 mg/mL
Host species
Rabbit
Specificity
Egr1
Immunogen
A synthetic peptide derived from human Egr1 (AA 50-200)
Positive Control
WB: 293T lysates.
Conjugation
Unconjugated
Grade
ExactAb™, Recombinant, Validated
Product Description
Rabbit anti Human Egr1 Antibody, Recombinant, could be used for WB and so on. Application: WB: 1/500-1/1000 Protein Function： Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-CGCCCCCGC-3'(EGR-site). Activates the transcription of target genes whose products are required for mitogenesis and differentiation.
Product Properties
Isotype
Rabbit IgG
Light Chain Type
kappa
SDS-PAGE
150 kDa
Purification Method
Protein A purified
Form
Liquid
Concentration
1.11 mg/mL
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
Associated Targets(Human)
EGR1TbioEarly growth response protein 1 (0 Activities)
1.Shimizu, N N and 6 more authors.. (1992) A gene coding for a zinc finger protein is induced during 12-O-tetradecanoylphorbol-13-acetate-stimulated HL-60 cell differentiation.. Journal of biochemistry, [PMID:1569051]
2.Wright, J J JJ and 5 more authors.. (1990) Expression of a zinc finger gene in HTLV-I- and HTLV-II-transformed cells.. Science (New York, N.Y.), (4):[PMID:2110381]
3.Suggs, S V SV, Katzowitz, J L JL, Tsai-Morris, C C and Sukhatme, V P VP.. (1990) cDNA sequence of the human cellular early growth response gene Egr-1.. Nucleic acids research, (25):[PMID:2377485]
4.Mayya, Viveka V and 7 more authors.. (2009) Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.. Science signaling, (18):[PMID:19690332]
5.Hu, Chi-Tan CT and 6 more authors.. (2010) Snail associates with EGR-1 and SP-1 to upregulate transcriptional activation of p15INK4b.. The FEBS journal, [PMID:20121949]
6.Cullen, Eva M EM, Brazil, Jennifer C JC and O'Connor, Clare M CM.. (2010) Mature human neutrophils constitutively express the transcription factor EGR-1.. Molecular immunology, [PMID:20363028]
7.Hashimoto, Hideharu H and 5 more authors.. (2014) Wilms tumor protein recognizes 5-carboxylcytosine within a specific DNA sequence.. Genes & development, (15):[PMID:25258363]
8.Zandarashvili, Levani; White, Mark A; Esadze, Alexandre and Iwahara, Junji.. (2015) Structural impact of complete CpG methylation within target DNA on specific complex formation of the inducible transcription factor Egr-1.. FEBS letters, (8):[PMID:25999311]
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