Recombinant EMAP II/AIMP1 Antibody - Primary antibody, specific to AIMP1, Rabbit IgG

    Application:
  • WB
Features and benefits
  • Host species: Rabbit
  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
Item Number
Ab101549
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab101549-10μl
10μl
In stock
$69.90
Ab101549-50μl
50μl
In stock
$199.90
Ab101549-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$329.90
Ab101549-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,999.90

Recombinant; Rabbit anti Human EMAP II/AIMP1 Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant EMAP II/AIMP1 Antibody - Primary antibody, specific to AIMP1, Rabbit IgG
SynonymsAIMP1 | p43 | HLD3 | EMAP2 | SCYE1 | EMAPII | AIMP 1 antibody | Aimp1 antibody | AIMP1/p43 antibody | AIMP1_HUMAN antibody | Aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 antibody | ARS interacting multifunctional protein 1 antib
Specifications & PurityExactAb™, Validated, Recombinant, 0.4 mg/mL
Host speciesRabbit
SpecificityAIMP1
ImmunogenA synthetic peptide derived from human EMAP II (AA 164-177)
Positive ControlWB: HeLa, HEK293, Hep G2, NIH/3T3 and C6 cell lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human EMAP II/AIMP1 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/1000
Protein Function:
Non-catalytic component of the multisynthase complex. Stimulates the catalytic activity of cytoplasmic arginyl-tRNA synthase. Binds tRNA. Possesses inflammatory cytokine activity. Negatively regulates TGF-beta signaling through stabilization of SMURF2 by binding to SMURF2 and inhibiting its SMAD7-mediated degradation. Involved in glucose homeostasis through induction of glucagon secretion at low glucose levels. Promotes dermal fibroblast proliferation and wound repair. Regulates KDELR1-mediated retention of HSP90B1/gp96 in the endoplasmic reticulum. Plays a role in angiogenesis by inducing endothelial cell migration at low concentrations and endothelian cell apoptosis at high concentrations. Induces maturation of dendritic cells and monocyte cell adhesion. Modulates endothelial cell responses by degrading HIF-1A through interaction with PSMA7.

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration0.4 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant EMAP II/AIMP1 Antibody (Ab101549) - Western Blot
All lanes: Recombinant EMAP II/AIMP1 Antibody (Ab101549) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 34 kDa
Observed band size: 34 kDa
Exposure time: 96.1 s

Recombinant EMAP II/AIMP1 Antibody (Ab101549) - Western Blot
All lanes: Recombinant EMAP II/AIMP1 Antibody (Ab101549) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 34 kDa
Observed band size: 32, 34 kDa
Exposure time: 120.0 s

Associated Targets(Human)

AIMP1 Tbio Aminoacyl tRNA synthase complex-interacting multifunctional protein 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Application

ApplicationDilution info
WB 1/1000

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1/1000

Certificates

Certificate of Analysis(COA)

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2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0505900Certificate of AnalysisMay 21, 2024 Ab101549
ZJ24F0505901Certificate of AnalysisMay 21, 2024 Ab101549

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