Basic Description

Product Name	Recombinant ERK2 Antibody - Primary antibody, specific to MAPK1, Rabbit IgG
Synonyms	ERK 2 antibody\|ERK-2 antibody\|ERT1 antibody\|Extracellular Signal Regulated Kinase 2 antibody\|Extracellular signal-regulated kinase 2 antibody\|MAP kinase 1 antibody\|MAP kinase 2 antibody\|MAP kinase isoform p42 antibody\|MAPK 1 antibody\|MAPK 2 antibody\|Mapk1
Specifications & Purity	ExactAb™, Validated, Recombinant, 0.5 mg/mL
Host species	Rabbit
Specificity	MAPK1
Immunogen	A synthetic peptide derived from human ERK2 (AA 340-360).
Positive Control	WB: K562, C6, NIH/3T3, HeLa, MCF7, A549, Hep G2, HEK293 lysates. IHC: Human Cholangiocarcinoma Tissue. ICC/IF: K562 cells.
Conjugation	Unconjugated
Grade	ExactAb™, Recombinant, Validated
Product Description	Rabbit anti Human ERK2 Antibody, Recombinant, could be used for WB, IHC, IF, ICC and so on. Application: WB: 1/500-1/1000 IHC: 1/50-1/100 IF/ICC: 1/50-1/200 Protein Function Involved in both the initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors such as ELK1. Phosphorylates EIF4EBP1; required for initiation of translation. Phosphorylates microtubule-associated protein 2 (MAP2). Phosphorylates SPZ1 (By similarity). Phosphorylates heat shock factor protein 4 (HSF4) and ARHGEF2. Acts as a transcriptional repressor. Binds to a [GC]AAA[GC] consensus sequence. Repress the expression of interferon gamma-induced genes. Seems to bind to the promoter of CCL5, DMP1, IFIH1, IFITM1, IRF7, IRF9, LAMP3, OAS1, OAS2, OAS3 and STAT1. Transcriptional activity is independent of kinase activity.

Product Properties

Isotype	Rabbit IgG
SDS-PAGE	150 kDa
Purification Method	Antigen affinity purified
Form	Liquid
Concentration	0.5 mg/mL
Storage Temp	Store at -20°C,Avoid repeated freezing and thawing
Shipped In	Ice chest + Ice pads
Stability And Storage	Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Associated Targets

MAPK1 Tchem Mitogen-activated protein kinase 1 0 Activities

Discover Target: MAPK1

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

Application

Application	Dilution info
WB	1/500-1/1000
IHC	1/50 - 1/100
IF/ICC	1/50 - 1/200

Certificates

Certificate of Analysis(COA)

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2 results found

Lot Number	Certificate Type	Date	Item
ZJ23F0800761	Certificate of Analysis	Aug 03, 2023	Ab102233
ZJ23F0800760	Certificate of Analysis	Aug 03, 2023	Ab102233

FAQs and Articles

References

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Recombinant ERK2 Antibody - Primary antibody, specific to MAPK1, Rabbit IgG