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Recombinant FMRP Antibody - Primary antibody, specific to FMRP, Rabbit IgG

  • ExactAb™
  • Recombinant
  • Validated
  • 1.0 mg/mL
Features and benefits
  • Short Overview:

    Recombinant; Rabbit anti Human FMRP Antibody; WB, IHC, ICC, IF; Unconjugated

  • Species reactivity(Reacts with): Human,Monkey,Mouse,Rat
  • Isotype: Rabbit IgG
    Application:
  • ICC/IF
  • IHC
  • WB
Item Number
Ab103843
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab103843-10μl
10μl
In stock
$69.90
Ab103843-50μl
50μl
In stock
$209.90
Ab103843-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$309.90
Ab103843-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,399.90

Recombinant; Rabbit anti Human FMRP Antibody; WB, IHC, ICC, IF; Unconjugated

Basic Description

Product NameRecombinant FMRP Antibody - Primary antibody, specific to FMRP, Rabbit IgG
Specifications & PurityExactAb™, Validated, Recombinant, 1.0 mg/mL
Host speciesRabbit
SpecificityFMRP
ImmunogenA synthetic peptide derived from human FMRP (AA 31-47)
Positive ControlWB: HEK293, U-2 OS, Jurkat, K562, HeLa, NIH/3T3 and C6 cell lysates. IHC: Human lung cancer tissue. ICC/IF: HeLa cells.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human FMRP Antibody, Recombinant, could be used for WB, IHC, ICC/IF and so on.
Application
WB: 1/500-1/1000
IHC: 1/50-1/100
ICC/IF: 1/50-1/200
Protein Function
Translation repressor. Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit mediates translation repression (By similarity). RNA-binding protein that plays a role in intracellular RNA transport and in the regulation of translation of target mRNAs. Associated with polysomes. May play a role in the transport of mRNA from the nucleus to the cytoplasm. Binds strongly to poly(G), binds moderately to poly(U) but shows very little binding to poly(A) or poly(C).

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodAntigen affinity purified
FormLiquid
Concentration1.0 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant FMRP Antibody (Ab103843) - Western Blot
All lanes: Recombinant FMRP Antibody (Ab103843) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution

Predicted band size: 71 kDa
Observed band size: 64-80 kDa
Exposure time: 22.8 s

Recombinant FMRP Antibody (Ab103843) - IF/ICC
Immunocytochemistry analysis of FMRP (green) in HeLa using Recombinant FMRP Antibody (Ab103843), and cells were counterstained with DAPI (blue).

Recombinant FMRP Antibody (Ab103843) - IHC
Immunohistochemistry analysis of paraffin-embedded Human lung cancer using Recombinant FMRP Antibody (Ab103843). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.

Associated Targets

FMR1 Tbio Synaptic functional regulator FMR1 0 Activities

Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB

1/500-1/1000

ICC/IF

1/50-1/200

IHC

1/50 - 1/100

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0506042Certificate of AnalysisMay 23, 2024 Ab103843
ZJ24F0506041Certificate of AnalysisMay 23, 2024 Ab103843

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