Rabbit anti Human Granzyme B Antibody, Recombinant (EP230), could be used for IHC and so on. Application IHC: 1/50-1/100 Protein Function This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.
Product Properties
Isotype
Rabbit IgG
SDS-PAGE
150 kDa
Purification Method
Protein A purified
Form
Liquid
Concentration
0.3 mg/mL
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
Images
Recombinant Granzyme B Antibody (Ab106347) - IHC Immunohistochemistry analysis of paraffin-embedded human spleen tissue labelling Granzyme B with Recombinant Granzyme B Antibody (Ab106347) at 1/100 dilution. The section was incubated with Ab106347 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.