Recombinant Granzyme B Antibody - Primary antibody, specific to Granzyme B, Rabbit IgG

    Application:
  • IHC
Features and benefits
  • Host species: Rabbit
  • Species reactivity(Reacts with): Human
  • Isotype: Rabbit IgG
  • Clone Number: EP230
  • Conjugation: Unconjugated
Item Number
Ab106347
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab106347-10μl
10μl
In stock
$39.90
Ab106347-50μl
50μl
In stock
$109.90
Ab106347-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$189.90
Ab106347-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$1,859.90

Recombinant (EP230); Rabbit anti Human Granzyme B Antibody; IHC; Unconjugated

Basic Description

Product NameRecombinant Granzyme B Antibody - Primary antibody, specific to Granzyme B, Rabbit IgG
SynonymsC11 antibody | Cathepsin G like 1 antibody | Cathepsin G-like 1 antibody | CCPI antibody | CGL 1 antibody | CGL1 antibody | CSP B antibody | CSPB antibody | CTLA 1 antibody | CTLA-1 antibody | CTLA1 antibody | CTSGL1 antibody | Cytotoxic serine protease B
Specifications & PurityExactAb™, Validated, Carrier Free, Recombinant, 0.3 mg/mL
Host speciesRabbit
SpecificityGranzyme B
ImmunogenFull length of human Granzyme B.
Positive ControlIHC: Human spleen tissue.
ConjugationUnconjugated
GradeCarrier Free, ExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human Granzyme B Antibody, Recombinant (EP230), could be used for IHC and so on.
Application
IHC: 1/50-1/100
Protein Function
This enzyme is necessary for target cell lysis in cell-mediated immune responses. It cleaves after Asp. Seems to be linked to an activation cascade of caspases (aspartate-specific cysteine proteases) responsible for apoptosis execution. Cleaves caspase-3, -7, -9 and 10 to give rise to active enzymes mediating apoptosis.

Product Properties

IsotypeRabbit IgG
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration0.3 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4℃ short term (1-2 weeks). Store at -20℃ long term (12 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant Granzyme B Antibody (Ab106347) - IHC
Immunohistochemistry analysis of paraffin-embedded human spleen tissue labelling Granzyme B with Recombinant Granzyme B Antibody (Ab106347) at 1/100 dilution. The section was incubated with Ab106347 for 30 mins at room temperature. Perform heat mediated antigen retrieval with Tris/EDTA buffer pH 9.0 was used for antigen retrieval.​

Associated Targets(Human)

GZMB Tchem Granzyme B (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Application

ApplicationDilution info
IHC1/50 - 1/100

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1/50 - 1/100

Certificates

Certificate of Analysis(COA)

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3 results found

Lot NumberCertificate TypeDateItem
ZJ24F0506362Certificate of AnalysisMay 31, 2024 Ab106347
ZJ24F0404727Certificate of AnalysisApr 22, 2024 Ab106347
ZJ24F0404726Certificate of AnalysisApr 22, 2024 Ab106347

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