| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab106687-10μl | 10μl | In stock | $69.90 | |
| Ab106687-50μl | 50μl | In stock | $199.90 | |
| Ab106687-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $289.90 | |
| Ab106687-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,699.90 |
Recombinant; Rabbit anti Human GSTM1 Antibody; WB; Unconjugated
| Product Name | Recombinant GSTM1 Antibody - Primary antibody, specific to GSTM1, Rabbit IgG |
|---|---|
| Synonyms | GST1-1 | EC 2.5.1.18 | glutathione S-alkyltransferase | glutathione S-aralkyltransferase | glutathione S-aryltransferase | glutathione S-transferase M1 | Glutathione STransferase mu 1 | Glutathione S-Transferase mu 1 | GST class-mu 1 | GST HB subunit 4 | |
| Specifications & Purity | ExactAb™, Validated, Recombinant, 0.7 mg/mL |
| Host species | Rabbit |
| Specificity | GSTM1 |
| Immunogen | A synthetic peptide derived from human GSTM1 (AA 103-114) |
| Positive Control | WB: Jurkat, Hep G2, HeLa and C6 cell lysates. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description |
Rabbit anti Human GSTM1 Antibody, Recombinant, could be used for WB and so on. |
| Isotype | Rabbit IgG |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Antigen affinity purified |
| Form | Liquid |
| Concentration | 0.7 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Recombinant GSTM1 Antibody (Ab106687) - Western Blot
All lanes: Recombinant GSTM1 Antibody (Ab106687) at 1/2000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 26 kDa
Observed band size: 28 kDa
Exposure time: 5.0 s
Recombinant GSTM1 Antibody (Ab106687) - Western Blot
All lanes: Recombinant GSTM1 Antibody (Ab106687) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 26 kDa
Observed band size: 28 kDa
Exposure time: 20.0 s
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Activity Type | Relation | Activity value | Units | Action Type | Journal | PubMed Id | doi | Assay Aladdin ID |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/500-1/2000 "> 1/500-1/2000 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0303779 | Certificate of Analysis | Mar 27, 2024 | Ab106687 |
| ZJ24F0303778 | Certificate of Analysis | Mar 27, 2024 | Ab106687 |
| 1. Chakrapani H, Kalathur RC, Maciag AE, Citro ML, Ji X, Keefer LK, Saavedra JE.. (2008) Synthesis, mechanistic studies, and anti-proliferative activity of glutathione/glutathione S-transferase-activated nitric oxide prodrugs.. Bioorg Med Chem, 16 (22): (9764-9771). [PMID:18930407] [10.1016/j.bmc.2008.09.063] |
| 2. Wang CH, Wu HT, Cheng HM, Yen TJ, Lu IH, Chang HC, Jao SC, Shing TK, Li WS.. (2011) Inhibition of glutathione S-transferase M1 by new gabosine analogues is essential for overcoming cisplatin resistance in lung cancer cells.. J Med Chem, 54 (24): (8574-8581). [PMID:22085405] [10.1021/jm201131n] |
| 3. Singhal, S S SS and 5 more authors.. (1992) Gender related differences in the expression and characteristics of glutathione S-transferases of human colon.. Biochimica et biophysica acta, (15): [PMID:1420361] |
| 4. Singhal, S S SS and 5 more authors.. (1991) Purification and characterization of human muscle glutathione S-transferases: evidence that glutathione S-transferase zeta corresponds to a locus distinct from GST1, GST2, and GST3.. Archives of biochemistry and biophysics, (15): [PMID:1846734] |
| 5. Tsuchida, S S, Maki, T T and Sato, K K.. (1990) Purification and characterization of glutathione transferases with an activity toward nitroglycerin from human aorta and heart. Multiplicity of the human class Mu forms.. The Journal of biological chemistry, (5): [PMID:2110160] |
| 6. Comstock, K E KE, Sanderson, B J BJ, Claflin, G G and Henner, W D WD.. (1990) GST1 gene deletion determined by polymerase chain reaction.. Nucleic acids research, (25): [PMID:2362832] |
| 7. Seidegård, J J, Vorachek, W R WR, Pero, R W RW and Pearson, W R WR.. (1988) Hereditary differences in the expression of the human glutathione transferase active on trans-stilbene oxide are due to a gene deletion.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:3174634] |
| 8. DeJong, J L JL, Chang, C M CM, Whang-Peng, J J, Knutsen, T T and Tu, C P CP.. (1988) The human liver glutathione S-transferase gene superfamily: expression and chromosome mapping of an Hb subunit cDNA.. Nucleic acids research, (12): [PMID:3419925] |
| 9. Mannervik, B B and 6 more authors.. (1985) Identification of three classes of cytosolic glutathione transferase common to several mammalian species: correlation between structural data and enzymatic properties.. Proceedings of the National Academy of Sciences of the United States of America, [PMID:3864155] |
| 10. Alin, P P, Mannervik, B B and Jörnvall, H H.. (1985) Structural evidence for three different types of glutathione transferase in human tissues.. FEBS letters, (25): [PMID:3979555] |
| 11. Mera, N N and 6 more authors.. (1994) Immunochemical evidence for the occurrence of Mu class glutathione S-transferase in human fetal livers.. Journal of biochemistry, [PMID:7822249] |
| 12. Pearson, W R WR and 6 more authors.. (1993) Identification of class-mu glutathione transferase genes GSTM1-GSTM5 on human chromosome 1p13.. American journal of human genetics, [PMID:8317488] |
| 13. Zhong, S S, Spurr, N K NK, Hayes, J D JD and Wolf, C R CR.. (1993) Deduced amino acid sequence, gene structure and chromosomal location of a novel human class Mu glutathione S-transferase, GSTM4.. The Biochemical journal, (1): [PMID:8471052] |
| 14. Patskovsky, Y V YV, Patskovska, L N LN and Listowsky, I I.. (1999) Functions of His107 in the catalytic mechanism of human glutathione S-transferase hGSTM1a-1a.. Biochemistry, (26): [PMID:9930979] |
| 15. Hubbard, M J MJ and McHugh, N J NJ.. (2000) Human ERp29: isolation, primary structural characterisation and two-dimensional gel mapping.. Electrophoresis, [PMID:11271497] |
| 16. Moore, Lee E LE and 14 more authors.. (2007) Polymorphisms in one-carbon metabolism and trans-sulfuration pathway genes and susceptibility to bladder cancer.. International journal of cancer, (1): [PMID:17311259] |
| 17. Schwartzbaum, Judith A JA and 14 more authors.. (2007) An international case-control study of glutathione transferase and functionally related polymorphisms and risk of primary adult brain tumors.. Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, [PMID:17372252] |
| 18. Ouerhani, Slah S and 7 more authors.. () The role of glutathione transferases M1 and T1 in individual susceptibility to bladder cancer in a Tunisian population.. Annals of human biology, [PMID:17381051] |
| 19. Sakoda, Lori C LC and 10 more authors.. (2008) Glutathione S-transferase M1 and P1 polymorphisms and risk of breast cancer and fibrocystic breast conditions in Chinese women.. Breast cancer research and treatment, [PMID:17624589] |
