Recombinant H-FABP Antibody - Primary antibody, for ELISA,CLIA,GICA,Capture antibody,FIA various applications, from Human, generated in Rat, specific to Human H-FABP, IgG1

    Application:
  • Capture Antibody
  • CLIA
  • ELISA
  • FIA
  • GICA
Features and benefits
  • Host species: Mouse
  • Species reactivity(Reacts with): Human
  • Isotype: Mouse IgG1
  • Clone Number: 26H2
  • Conjugation: Unconjugated
Item Number
Ab107394
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab107394-10μg
10μg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$26.90
Ab107394-50μg
50μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$78.90
Ab107394-100μg
100μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$138.90
Ab107394-1mg
1mg
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$627.90

Recombinant(26H2); Mouse anti Human H-FABP antibody; Capture antibody, ELISA, CLIA, FIA; Unconjugated

Basic Description

Product NameRecombinant H-FABP Antibody - Primary antibody, for ELISA,CLIA,GICA,Capture antibody,FIA various applications, from Human, generated in Rat, specific to Human H-FABP, IgG1
Synonyms422 protein antibody | Cardiac FABP antibody | Cardiac Fatty Acid Binding Protein antibody | FABP 11 antibody | FABP 3 antibody | FABP11 antibody | FABP3 antibody | FABPH_HUMAN antibody | Fatty acid binding protein 11 antibody | Fatty acid binding protein
Specifications & PurityExactAb™, Validated, Carrier Free, Azide Free, Recombinant, Lot by Lot
Host SpeciesRat
Host speciesMouse
SpecificityHuman H-FABP
ApplicationELISA,CLIA,GICA,Capture antibody,FIA
ImmunogenE. coli-derived recombinant human H-FABP(Met1-Ala133)
ConjugationUnconjugated
GradeAzide Free, Carrier Free, ExactAb™, Recombinant, Validated
Product Description

Applications
Capture antibody
CLIA: 1μg/mL
ELISA: 1μg/mL
FIA: 1mg/mL

Function
FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters.

Product Properties

Antibody TypePrimary antibody
ClonalityRecombinant
IsotypeIgG1
SDS-PAGE150 kDa
Purification MethodProtein A purified
Matched Pairs[Ab007972] Recombinant H-FABP Antibody as detection antibody in ELISA, CLIA
SourceCHO supernatant
FormLiquid
ConcentrationLot by Lot
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at -20±5℃ for three years. Avoid freeze/thaw.

Associated Targets(Human)

FABP3 Tchem Fatty acid-binding protein, heart (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Mechanisms of Action

Mechanism of ActionAction Typetarget IDTarget NameTarget TypeTarget OrganismBinding Site NameReferences

Application

ApplicationDilution info
FIA

1 mg/mL

ELISA

1 μg/mL

CLIA

1 μg/mL

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
ZJ23F0500231Certificate of AnalysisJun 05, 2023 Ab107394
ZJ23F0500229Certificate of AnalysisJun 05, 2023 Ab107394

Related Documents

References

1. Hertzel AV, Hellberg K, Reynolds JM, Kruse AC, Juhlmann BE, Smith AJ, Sanders MA, Ohlendorf DH, Suttles J, Bernlohr DA.  (2009)  Identification and characterization of a small molecule inhibitor of Fatty Acid binding proteins..  J Med Chem,  52  (19): (6024-31).  [PMID:19754198] [10.1021/op500134e]
2. Young AC, Scapin G, Kromminga A, Patel SB, Veerkamp JH, Sacchettini JC.  (1994)  Structural studies on human muscle fatty acid binding protein at 1.4 A resolution: binding interactions with three C18 fatty acids..  Structure,  (6): (523-34).  [PMID:7922029] [10.1021/op500134e]
3. Liu X, Huang X, Lin W, Wang D, Diao Y, Li H, Hui X, Wang Y, Xu A, Wu D et al..  (2011)  New aromatic substituted pyrazoles as selective inhibitors of human adipocyte fatty acid-binding protein..  Bioorg Med Chem Lett,  21  (10): (2949-52).  [PMID:21481589] [10.1021/op500134e]
4. Haiyan Cai,Guirui Yan,Xiaodong Zhang,Olena Gorbenko,Heyao Wang,Weiliang Zhu.  (2010-05-18)  Discovery of highly selective inhibitors of human fatty acid binding protein 4 (FABP4) by virtual screening..  Bioorganic & medicinal chemistry letters,  20  ((12)): (3675-3679).  [PMID:20471252]
5. Lehmann F, Haile S, Axen E, Medina C, Uppenberg J, Svensson S, Lundbäck T, Rondahl L, Barf T..  (2004)  Discovery of inhibitors of human adipocyte fatty acid-binding protein, a potential type 2 diabetes target..  Bioorg Med Chem Lett,  14  (17): (4445-4448).  [PMID:15357969] [10.1016/j.bmcl.2004.06.057]
6. Barf T, Lehmann F, Hammer K, Haile S, Axen E, Medina C, Uppenberg J, Svensson S, Rondahl L, Lundbäck T..  (2009)  N-Benzyl-indolo carboxylic acids: Design and synthesis of potent and selective adipocyte fatty-acid binding protein (A-FABP) inhibitors..  Bioorg Med Chem Lett,  19  (6): (1745-1748).  [PMID:19217286] [10.1016/j.bmcl.2009.01.084]
7. Cai H, Liu Q, Gao D, Wang T, Chen T, Yan G, Chen K, Xu Y, Wang H, Li Y, Zhu W..  (2015)  Novel fatty acid binding protein 4 (FABP4) inhibitors: virtual screening, synthesis and crystal structure determination..  Eur J Med Chem,  90  (241-250).  [PMID:25461324] [10.1016/j.ejmech.2014.11.020]
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9. Kühne H, Obst-Sander U, Kuhn B, Conte A, Ceccarelli SM, Neidhart W, Rudolph MG, Ottaviani G, Gasser R, So SS, Li S, Zhang X, Gao L, Myers M..  (2016)  Design and synthesis of selective, dual fatty acid binding protein 4 and 5 inhibitors..  Bioorg Med Chem Lett,  26  (20): (5092-5097).  [PMID:27658368] [10.1016/j.bmcl.2016.08.071]
10. Gao DD, Dou HX, Su HX, Zhang MM, Wang T, Liu QF, Cai HY, Ding HP, Yang Z, Zhu WL, Xu YC, Wang HY, Li YX..  (2018)  From hit to lead: Structure-based discovery of naphthalene-1-sulfonamide derivatives as potent and selective inhibitors of fatty acid binding protein 4..  Eur J Med Chem,  154  (44-59).  [PMID:29775936] [10.1016/j.ejmech.2018.05.007]
11. Yan S, Elmes MW, Tong S, Hu K, Awwa M, Teng GYH, Jing Y, Freitag M, Gan Q, Clement T, Wei L, Sweeney JM, Joseph OM, Che J, Carbonetti GS, Wang L, Bogdan DM, Falcone J, Smietalo N, Zhou Y, Ralph B, Hsu HC, Li H, Rizzo RC, Deutsch DG, Kaczocha M, Ojima I..  (2018)  SAR studies on truxillic acid mono esters as a new class of antinociceptive agents targeting fatty acid binding proteins..  Eur J Med Chem,  154  (233-252).  [PMID:29803996] [10.1016/j.ejmech.2018.04.050]
12. He Y, Dou H, Gao D, Wang T, Zhang M, Wang H, Li Y..  (2019)  Identification of new dual FABP4/5 inhibitors based on a naphthalene-1-sulfonamide FABP4 inhibitor..  Bioorg Med Chem,  27  (19): (115015-115015).  [PMID:31420256] [10.1016/j.bmc.2019.07.031]
13. Zanotti, G G, Scapin, G G, Spadon, P P, Veerkamp, J H JH and Sacchettini, J C JC..  (1992)  Three-dimensional structure of recombinant human muscle fatty acid-binding protein..  The Journal of biological chemistry,    (15):   [PMID:1526991]
14. Peeters, R A RA, Veerkamp, J H JH, Geurts van Kessel, A A, Kanda, T T and Ono, T T..  (1991)  Cloning of the cDNA encoding human skeletal-muscle fatty-acid-binding protein, its peptide sequence and chromosomal localization..  The Biochemical journal,    (15):   [PMID:1710107]
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