| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab108605-10μl | 10μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $69.90 | |
| Ab108605-50μl | 50μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $189.90 | |
| Ab108605-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $289.90 | |
| Ab108605-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,699.90 |
Recombinant; Rabbit anti Human HP1 alphaAntibody; WB, IF/ICC; Unconjugated
| Product Name | Recombinant HP1 alpha Antibody |
|---|---|
| Synonyms | CBX5 | HP1 | HP1A | HEL25 | HP1alpha | Antigen p25 antibody | CBX5 antibody | CBX5_HUMAN antibody | CG8409 antibody | Chromobox 5 antibody | Chromobox homolog 5 (HP1 alpha homolog, Drosophila) antibody | Chromobox homolog 5 antibody | Chromobox protein ho |
| Specifications & Purity | Recombinant, ExactAb™, Validated, See COA |
| Biochemical and Physiological Mechanisms | Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with |
| Host species | Rabbit |
| Specificity | CBX5 |
| Immunogen | A synthetic peptide derived from human CBX5 (AA 141-191) |
| Positive Control | WB: THP-1, Jurkat, Raji, HeLa, HEK293, SH-SY5Y, NIH/3T3 and C6 cell lysates. IF/ICC: HeLa cells. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description |
Rabbit anti Human HP1 alpha Antibody, Recombinant, could be used for WB, IF/ICC and so on.
|
| Isotype | Rabbit IgG |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | See COA |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Recombinant HP1 alpha Antibody (Ab108605) - Western Blot
All lanes: Recombinant HP1 alpha Antibody (Ab108605) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab176443) at 1/20000 dilution
Predicted band size: 22 kDa
Observed band size: 24 kDa
Exposure time: 6.0 s
Recombinant HP1 alpha Antibody (Ab108605) - IF/ICC
Immunofluorescent analysis of HeLa cells, using Recombinant HP1 alpha Antibody (Ab108605) at 1/50 dilution.
Recombinant HP1 alpha Antibody (Ab108605) - IF/ICC
Immunofluorescent analysis of HeLa cells, using Recombinant HP1 alpha Antibody (Ab108605) at 1/150 dilution.
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Mechanism of Action | Action Type | target ID | Target Name | Target Type | Target Organism | Binding Site Name | References |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/1000 - 1/2000"> 1/1000 - 1/2000 |
| IF/ICC | 1/50 - 1/200 "> 1/50 - 1/200 |
Enter Lot Number to search for COA:
