Recombinant Human GM-CSF, CAS No.83869-56-1

  • ≥98%
Features and benefits
  • Accession #: P04141
  • Bioactivity: The ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
  • Endotoxin Concentration: <1.0 EU/μg
Item Number
G329704
Grouped product items
SKUSizeAvailabilityPrice Qty
G329704-5μg
5μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$490.90
G329704-20μg
20μg
Available within 4-8 weeks(?)
Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!
$1,764.90

a growth factor for in vitro colony formations of various progenitors

Basic Description

Product NameRecombinant Human GM-CSF, CAS No.83869-56-1
Product Description

Product Describtion:

GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages, and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant Human GM-CSF is a 14.6 kDa globular protein consisting of 128 amino acids, containing two intramolecular disulfide bonds and two potential N-linked glycosylation sites.

Initially reconstitute in water to 0.1-1.0 mg/ml. Store at 2°C to 8°C for up to 1 week or prepare for extended storage.

After initial reconstitution, further dilute in a buffer containing a carrier protein or stabilizer (e.g. 0.1% BSA). Store working aliquots at -20˚C to -80˚C.

Accession Number: P04141

Specifications & Purity≥98%
BioactivityThe ED50 as determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is ≤ 0.1 ng/ml, corresponding to a specific activity of ≥ 1 x 107 units/mg.
Endotoxin Concentration<1.0 EU/μg
Amino Acids18-144 aa
SequenceAA Sequence:MAPARSPSPS TQPWEHVNAI QEARRLLNLS RDTAAEMNET VEVISEMFDL QEPTCLQTRL ELYKQGLRGS LTKLKGPLTM MASHYKQHCP PTPETSCATQ IITFESFKEN LKDFLLVIPF DCWEPVQE
Accession #P04141
Predicted molecular weight14.6 kDa

Associated Targets(Human)

CSF2 Tbio Granulocyte-macrophage colony-stimulating factor (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Product Specifications

Storage TempStore at -80°C
Shipped InIce chest + Ice pads
CAS83869-56-1

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2 results found

Lot NumberCertificate TypeDateItem
H2205200Certificate of AnalysisJul 27, 2022 G329704
H2205201Certificate of AnalysisJul 27, 2022 G329704

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