Recombinant Iba1 Antibody - Primary antibody, specific to AIF1, Rabbit IgG

    Application:
  • WB
Features and benefits
  • Host species: Rabbit
  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
Item Number
Ab109181
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab109181-10μl
10μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$79.90
Ab109181-50μl
50μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$239.90
Ab109181-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$379.90
Ab109181-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,199.90

Recombinant; Rabbit anti Human Iba1 Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant Iba1 Antibody - Primary antibody, specific to AIF1, Rabbit IgG
SynonymsAIF 1 antibody | AIF-1 antibody | Aif1 antibody | AIF1 protein antibody | AIF1_HUMAN antibody | Allograft inflammatory factor 1 antibody | Allograft inflammatory factor 1 splice variant G antibody | allograft inflammatory factor-1 splice variant Hara-1 an
Specifications & PurityRecombinant, ExactAb™, Validated, See COA
Biochemical and Physiological MechanismsActin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the p
Host speciesRabbit
SpecificityAIF1
ImmunogenA synthetic peptide derived from human Iba1 (AA 1-38)
Positive ControlWB: Rat spleen, Mouse liver, U937, THP-1, HEL and HL60 lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human Iba1 Antibody, Recombinant, could be used for WB and so on.

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
ConcentrationSee COA
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Associated Targets(Human)

AIF1 Tbio Allograft inflammatory factor 1 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB1/1000 - 1/2000

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1/1000 - 1/2000

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Related Documents

References

1. Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.  (2009)  Lysine acetylation targets protein complexes and co-regulates major cellular functions..  Science,  325  (5942): (834-40).  [PMID:19608861] [10.1021/op500134e]
2. Holzinger, I I and 5 more authors..  (1995)  Cloning and genomic characterization of LST1: a new gene in the human TNF region..  Immunogenetics,      [PMID:7590964]
3. Albertella, M R MR and Campbell, R D RD..  (1994)  Characterization of a novel gene in the human major histocompatibility complex that encodes a potential new member of the I kappa B family of proteins..  Human molecular genetics,      [PMID:8081366]
4. Utans, U U and 6 more authors..  (1996)  Allograft inflammatory factory-1. A cytokine-responsive macrophage molecule expressed in transplanted human hearts..  Transplantation,    (15):   [PMID:8629302]
5. and Autieri, M V MV..  (1996)  cDNA cloning of human allograft inflammatory factor-1: tissue distribution, cytokine induction, and mRNA expression in injured rat carotid arteries..  Biochemical and biophysical research communications,    (1):   [PMID:8912632]
6. de Baey, A A and 5 more authors..  (1997)  Complex expression pattern of the TNF region gene LST1 through differential regulation, initiation, and alternative splicing..  Genomics,    (1):   [PMID:9367684]
7. Neville, M J MJ and Campbell, R D RD..  (1999)  A new member of the Ig superfamily and a V-ATPase G subunit are among the predicted products of novel genes close to the TNF locus in the human MHC..  Journal of immunology (Baltimore, Md. : 1950),    (15):   [PMID:10202016]
8. Xie, Tao T and 7 more authors..  (2003)  Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse..  Genome research,      [PMID:14656967]
9. Chen, Xing X, Kelemen, Sheri E SE and Autieri, Michael V MV..  (2004)  AIF-1 expression modulates proliferation of human vascular smooth muscle cells by autocrine expression of G-CSF..  Arteriosclerosis, thrombosis, and vascular biology,      [PMID:15117732]
10. Kelemen, Sheri E SE and Autieri, Michael V MV..  (2005)  Expression of allograft inflammatory factor-1 in T lymphocytes: a role in T-lymphocyte activation and proliferative arteriopathies..  The American journal of pathology,      [PMID:16049345]
11. Yamada, Mitsugu M, Ohsawa, Keiko K, Imai, Yoshinori Y, Kohsaka, Shinichi S and Kamitori, Shigehiro S..  (2006)  X-ray structures of the microglia/macrophage-specific protein Iba1 from human and mouse demonstrate novel molecular conformation change induced by calcium binding..  Journal of molecular biology,    (1):   [PMID:17011575]
12. Schulze, Jörg O JO and 11 more authors..  (2008)  Structural and functional characterization of human Iba proteins..  The FEBS journal,      [PMID:18699778]
13. Zhou, Houjiang H and 6 more authors..  (2013)  Toward a comprehensive characterization of a human cancer cell phosphoproteome..  Journal of proteome research,    (4):   [PMID:23186163]

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