Determine the necessary mass, volume, or concentration for preparing a solution.
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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SKU | Size | Availability | Price | Qty |
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Ab109181-10μl | 10μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $79.90 | |
Ab109181-50μl | 50μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $239.90 | |
Ab109181-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $379.90 | |
Ab109181-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,199.90 |
Recombinant; Rabbit anti Human Iba1 Antibody; WB; Unconjugated
Product Name | Recombinant Iba1 Antibody - Primary antibody, specific to AIF1, Rabbit IgG |
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Synonyms | AIF 1 antibody | AIF-1 antibody | Aif1 antibody | AIF1 protein antibody | AIF1_HUMAN antibody | Allograft inflammatory factor 1 antibody | Allograft inflammatory factor 1 splice variant G antibody | allograft inflammatory factor-1 splice variant Hara-1 an |
Specifications & Purity | Recombinant, ExactAb™, Validated, See COA |
Biochemical and Physiological Mechanisms | Actin-binding protein that enhances membrane ruffling and RAC activation. Enhances the actin-bundling activity of LCP1. Binds calcium. Plays a role in RAC signaling and in phagocytosis. May play a role in macrophage activation and function. Promotes the p |
Host species | Rabbit |
Specificity | AIF1 |
Immunogen | A synthetic peptide derived from human Iba1 (AA 1-38) |
Positive Control | WB: Rat spleen, Mouse liver, U937, THP-1, HEL and HL60 lysates. |
Conjugation | Unconjugated |
Grade | ExactAb™, Recombinant, Validated |
Product Description |
Rabbit anti Human Iba1 Antibody, Recombinant, could be used for WB and so on.
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Isotype | Rabbit IgG |
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Light Chain Type | kappa |
SDS-PAGE | 150 kDa |
Purification Method | Protein A purified |
Form | Liquid |
Concentration | See COA |
Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
Shipped In | Ice chest + Ice pads |
Stability And Storage | Store at 4℃ short term (1-2 weeks). Store at -20℃ long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
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Application | Dilution info |
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WB | 1/1000 - 1/2000"> 1/1000 - 1/2000 |
Enter Lot Number to search for COA:
1. Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M. (2009) Lysine acetylation targets protein complexes and co-regulates major cellular functions.. Science, 325 (5942): (834-40). [PMID:19608861] [10.1021/op500134e] |
2. Holzinger, I I and 5 more authors.. (1995) Cloning and genomic characterization of LST1: a new gene in the human TNF region.. Immunogenetics, [PMID:7590964] |
3. Albertella, M R MR and Campbell, R D RD.. (1994) Characterization of a novel gene in the human major histocompatibility complex that encodes a potential new member of the I kappa B family of proteins.. Human molecular genetics, [PMID:8081366] |
4. Utans, U U and 6 more authors.. (1996) Allograft inflammatory factory-1. A cytokine-responsive macrophage molecule expressed in transplanted human hearts.. Transplantation, (15): [PMID:8629302] |
5. and Autieri, M V MV.. (1996) cDNA cloning of human allograft inflammatory factor-1: tissue distribution, cytokine induction, and mRNA expression in injured rat carotid arteries.. Biochemical and biophysical research communications, (1): [PMID:8912632] |
6. de Baey, A A and 5 more authors.. (1997) Complex expression pattern of the TNF region gene LST1 through differential regulation, initiation, and alternative splicing.. Genomics, (1): [PMID:9367684] |
7. Neville, M J MJ and Campbell, R D RD.. (1999) A new member of the Ig superfamily and a V-ATPase G subunit are among the predicted products of novel genes close to the TNF locus in the human MHC.. Journal of immunology (Baltimore, Md. : 1950), (15): [PMID:10202016] |
8. Xie, Tao T and 7 more authors.. (2003) Analysis of the gene-dense major histocompatibility complex class III region and its comparison to mouse.. Genome research, [PMID:14656967] |
9. Chen, Xing X, Kelemen, Sheri E SE and Autieri, Michael V MV.. (2004) AIF-1 expression modulates proliferation of human vascular smooth muscle cells by autocrine expression of G-CSF.. Arteriosclerosis, thrombosis, and vascular biology, [PMID:15117732] |
10. Kelemen, Sheri E SE and Autieri, Michael V MV.. (2005) Expression of allograft inflammatory factor-1 in T lymphocytes: a role in T-lymphocyte activation and proliferative arteriopathies.. The American journal of pathology, [PMID:16049345] |
11. Yamada, Mitsugu M, Ohsawa, Keiko K, Imai, Yoshinori Y, Kohsaka, Shinichi S and Kamitori, Shigehiro S.. (2006) X-ray structures of the microglia/macrophage-specific protein Iba1 from human and mouse demonstrate novel molecular conformation change induced by calcium binding.. Journal of molecular biology, (1): [PMID:17011575] |
12. Schulze, Jörg O JO and 11 more authors.. (2008) Structural and functional characterization of human Iba proteins.. The FEBS journal, [PMID:18699778] |
13. Zhou, Houjiang H and 6 more authors.. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome.. Journal of proteome research, (4): [PMID:23186163] |