| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab109944-10μl | 10μl | In stock | $66.90 | |
| Ab109944-50μl | 50μl | In stock | $199.90 | |
| Ab109944-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $299.90 | |
| Ab109944-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,399.90 |
Recombinant; Rabbit anti Human IL-15RA Antibody; WB; Unconjugated
| Product Name | Recombinant IL-15RA Antibody - Primary antibody, specific to IL15RA, Rabbit IgG |
|---|---|
| Synonyms | AA690181 antibody | CD215 antibody | I15RA_HUMAN antibody | IL 15R alpha antibody | IL-15 receptor subunit alpha antibody | IL-15R-alpha antibody | IL-15RA antibody | Il15ra antibody | Interleukin 15 receptor alpha antibody | Interleukin 15 receptor subun |
| Specifications & Purity | ExactAb™, Validated, Recombinant, 1.0 mg/mL |
| Host species | Rabbit |
| Specificity | IL15RA |
| Immunogen | A synthetic peptide derived from human IL15RA (AA 118-202) |
| Positive Control | WB: Raji lysates. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description |
Rabbit anti Human IL-15RA Antibody, Recombinant, could be used for WB and so on. |
| Isotype | Rabbit IgG |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | 1.0 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Recombinant IL-15RA Antibody (Ab109944) - Western Blot
All lanes: Recombinant IL-15RA Antibody (Ab109944) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 28 kDa
Observed band size: 42 kDa
Exposure time: 200.0 s
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/500-1/1000"> 1/500-1/1000 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0505751 | Certificate of Analysis | May 16, 2024 | Ab109944 |
| ZJ24F0505750 | Certificate of Analysis | May 16, 2024 | Ab109944 |
| 1. Anderson DM, Kumaki S, Ahdieh M, Bertles J, Tometsko M, Loomis A, Giri J, Copeland NG, Gilbert DJ, Jenkins NA et al.. (1995) Functional characterization of the human interleukin-15 receptor alpha chain and close linkage of IL15RA and IL2RA genes.. J Biol Chem, 270 (50): (29862-9). [PMID:8530383] [10.1021/op500134e] |
| 2. Quéméner A, Maillasson M, Arzel L, Sicard B, Vomiandry R, Mortier E, Dubreuil D, Jacques Y, Lebreton J, Mathé-Allainmat M. (2017) Discovery of a Small-Molecule Inhibitor of Interleukin 15: Pharmacophore-Based Virtual Screening and Hit Optimization.. J Med Chem, 60 (14): (6249-6272). [PMID:28657314] [10.1021/op500134e] |
| 3. Zhu X, Marcus WD, Xu W, Lee HI, Han K, Egan JO, Yovandich JL, Rhode PR, Wong HC. (2009) Novel human interleukin-15 agonists.. J Immunol, 183 (6): (3598-607). [PMID:19710453] [10.1021/op500134e] |
| 4. Han KP, Zhu X, Liu B, Jeng E, Kong L, Yovandich JL, Vyas VV, Marcus WD, Chavaillaz PA, Romero CA et al.. (2011) IL-15:IL-15 receptor alpha superagonist complex: high-level co-expression in recombinant mammalian cells, purification and characterization.. Cytokine, 56 (3): (804-10). [PMID:22019703] [10.1021/op500134e] |
| 5. Żyżyńska-Granica B, Trzaskowski B, Niewieczerzał S, Filipek S, Zegrocka-Stendel O, Dutkiewicz M, Krzeczyński P, Kowalewska M, Koziak K.. (2017) Pharmacophore guided discovery of small-molecule interleukin 15 inhibitors.. Eur J Med Chem, 136 (543-547). [PMID:28535470] [10.1016/j.ejmech.2017.05.034] |
| 6. Yu, W W and 9 more authors.. (1997) Large-scale concatenation cDNA sequencing.. Genome research, [PMID:9110174] |
| 7. Dubois, S S and 9 more authors.. (1999) Natural splicing of exon 2 of human interleukin-15 receptor alpha-chain mRNA results in a shortened form with a distinct pattern of expression.. The Journal of biological chemistry, (17): [PMID:10480910] |
| 8. Bulanova, E E and 6 more authors.. (2001) The IL-15R alpha chain signals through association with Syk in human B cells.. Journal of immunology (Baltimore, Md. : 1950), (1): [PMID:11714793] |
| 9. Kurowska, M M, Rudnicka, W W, Maślińska, D D and Maśliński, W W.. (2002) Expression of IL-15 and IL-15 receptor isoforms in select structures of human fetal brain.. Annals of the New York Academy of Sciences, [PMID:12114302] |
| 10. Bernard, Jérôme J and 11 more authors.. (2004) Identification of an interleukin-15alpha receptor-binding site on human interleukin-15.. The Journal of biological chemistry, (4): [PMID:15039446] |
| 11. Ratthé, Claude C and Girard, Denis D.. (2004) Interleukin-15 enhances human neutrophil phagocytosis by a Syk-dependent mechanism: importance of the IL-15Ralpha chain.. Journal of leukocyte biology, [PMID:15123770] |
| 12. Deloukas, P P and 135 more authors.. (2004) The DNA sequence and comparative analysis of human chromosome 10.. Nature, (27): [PMID:15164054] |
| 13. Mortier, Erwan E, Bernard, Jérôme J, Plet, Ariane A and Jacques, Yannick Y.. (2004) Natural, proteolytic release of a soluble form of human IL-15 receptor alpha-chain that behaves as a specific, high affinity IL-15 antagonist.. Journal of immunology (Baltimore, Md. : 1950), (1): [PMID:15265897] |
| 14. Lorenzen, Inken I, Dingley, Andrew J AJ, Jacques, Yannick Y and Grötzinger, Joachim J.. (2006) The structure of the interleukin-15 alpha receptor and its implications for ligand binding.. The Journal of biological chemistry, (10): [PMID:16377614] |
