Recombinant; Rabbit anti Human IMP3 Antibody; WB, ICC, IF; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab110488-10μl | 10μl | In stock | $66.90 | |
| Ab110488-50μl | 50μl | In stock | $199.90 | |
| Ab110488-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $299.90 | |
| Ab110488-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,799.90 |
Recombinant; Rabbit anti Human IMP3 Antibody; WB, ICC, IF; Unconjugated
| Product Name | Recombinant IMP3 Antibody - Primary antibody, specific to IGF2BP3, Rabbit IgG |
|---|---|
| Synonyms | Cancer/testis antigen 98 antibody; CT98 antibody; DKFZp686F1078 antibody; hKOC antibody; IF2B3_HUMAN antibody; IGF II mRNA binding protein 3 antibody; IGF-II mRNA-binding protein 3 antibody; IGF2 mRNA binding protein 3 antibody; IGF2 mRNA-binding protein |
| Specifications & Purity | ExactAb™, Validated, Recombinant, 0.2 mg/mL |
| Host species | Rabbit |
| Specificity | IGF2BP3 |
| Immunogen | A synthetic peptide derived from human IMP3 (AA 2-194) |
| Positive Control | WB: K562, HeLa, Hep G2, HEK293, HT-29, and NIH/3T3 cell lysates. ICC/IF: HeLa cells. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description |
Rabbit anti Human IMP3 Antibody, Recombinant, could be used for WB, ICC, IF and so on. |
| Isotype | Rabbit IgG |
|---|---|
| SDS-PAGE | 150 kDa |
| Purification Method | Antigen affinity purified |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Recombinant IMP3 Antibody (Ab110488) - Western Blot
All lanes: Recombinant IMP3 Antibody (Ab110488) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 64 kDa
Observed band size: 70 kDa
Exposure time: 14.5 s
Recombinant IMP3 Antibody (Ab110488) - IF/ICC
Immunocytochemistry analysis of IMP3 (green) in HeLa using Recombinant IMP3 Antibody (Ab110488), and cells were counterstained with DAPI (blue).
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/500-1/1000 |
| IF/ICC | 1/50 - 1/200 |
Enter Lot Number to search for COA:
Find and download the COA for your product by matching the lot number on the packaging.
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0102418 | Certificate of Analysis | Jan 10, 2024 | Ab110488 |
| ZJ24F0102417 | Certificate of Analysis | Jan 10, 2024 | Ab110488 |
| 1. Müeller-Pillasch, F F and 12 more authors.. (1997) Cloning of a gene highly overexpressed in cancer coding for a novel KH-domain containing protein.. Oncogene, (5): [PMID:9178771] |
| 2. Nielsen, J J and 5 more authors.. (1999) A family of insulin-like growth factor II mRNA-binding proteins represses translation in late development.. Molecular and cellular biology, [PMID:9891060] |
| 3. Mueller-Pillasch, F F and 9 more authors.. (1999) Expression of the highly conserved RNA binding protein KOC in embryogenesis.. Mechanisms of development, [PMID:10525192] |
| 4. Zhang, J Y JY and 6 more authors.. (2001) Autoimmune responses to mRNA binding proteins p62 and Koc in diverse malignancies.. Clinical immunology (Orlando, Fla.), [PMID:11465943] |
| 5. Monk, D D and 7 more authors.. (2002) Characterisation of the growth regulating gene IMP3, a candidate for Silver-Russell syndrome.. Journal of medical genetics, [PMID:12161597] |
| 6. Hillier, Ladeana W LW and 106 more authors.. (2003) The DNA sequence of human chromosome 7.. Nature, (10): [PMID:12853948] |
| 7. Nielsen, Jacob J and 6 more authors.. (2003) Nuclear transit of human zipcode-binding protein IMP1.. The Biochemical journal, (1): [PMID:12921532] |
| 8. Yisraeli, Joel K JK.. (2005) VICKZ proteins: a multi-talented family of regulatory RNA-binding proteins.. Biology of the cell, [PMID:15601260] |
| 9. Yantiss, Rhonda K RK and 8 more authors.. (2005) KOC (K homology domain containing protein overexpressed in cancer): a novel molecular marker that distinguishes between benign and malignant lesions of the pancreas.. The American journal of surgical pathology, [PMID:15644775] |
| 10. Hammer, Niels A NA and 8 more authors.. (2005) Expression of IGF-II mRNA-binding proteins (IMPs) in gonads and testicular cancer.. Reproduction (Cambridge, England), [PMID:16049158] |
| 11. Vikesaa, Jonas J and 6 more authors.. (2006) RNA-binding IMPs promote cell adhesion and invadopodia formation.. The EMBO journal, (5): [PMID:16541107] |
| 12. Jiang, Zhong Z and 10 more authors.. (2006) Analysis of RNA-binding protein IMP3 to predict metastasis and prognosis of renal-cell carcinoma: a retrospective study.. The Lancet. Oncology, [PMID:16814207] |
| 13. Li, Cuizhen C and 5 more authors.. (2007) IMP3 is a novel biomarker for adenocarcinoma in situ of the uterine cervix: an immunohistochemical study in comparison with p16(INK4a) expression.. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc, [PMID:17192788] |
| 14. Jønson, Lars L and 8 more authors.. (2007) Molecular composition of IMP1 ribonucleoprotein granules.. Molecular & cellular proteomics : MCP, [PMID:17289661] |
| 15. Bechtel, Stephanie S and 18 more authors.. (2007) The full-ORF clone resource of the German cDNA Consortium.. BMC genomics, (31): [PMID:17974005] |
| 16. Dephoure, Noah N and 6 more authors.. (2008) A quantitative atlas of mitotic phosphorylation.. Proceedings of the National Academy of Sciences of the United States of America, (5): [PMID:18669648] |
| 17. Mayya, Viveka V and 7 more authors.. (2009) Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.. Science signaling, (18): [PMID:19690332] |
| 18. Chao, Jeffrey A JA and 5 more authors.. (2010) ZBP1 recognition of beta-actin zipcode induces RNA looping.. Genes & development, (15): [PMID:20080952] |
| 19. Rigbolt, Kristoffer T G KT and 9 more authors.. (2011) System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.. Science signaling, (15): [PMID:21406692] |
| 20. Zhou, Houjiang H and 6 more authors.. (2013) Toward a comprehensive characterization of a human cancer cell phosphoproteome.. Journal of proteome research, (4): [PMID:23186163] |
| 21. Wächter, Kristin K, Köhn, Marcel M, Stöhr, Nadine N and Hüttelmaier, Stefan S.. (2013) Subcellular localization and RNP formation of IGF2BPs (IGF2 mRNA-binding proteins) is modulated by distinct RNA-binding domains.. Biological chemistry, [PMID:23640942] |
| 22. Huang, Huilin and 29 more authors.. (2018) Recognition of RNA N6-methyladenosine by IGF2BP proteins enhances mRNA stability and translation.. Nature cell biology, [PMID:29476152] |
| 23. Thomas R Burkard,Melanie Planyavsky,Ines Kaupe,Florian P Breitwieser,Tilmann Bürckstümmer,Keiryn L Bennett,Giulio Superti-Furga,Jacques Colinge. (2011-01-29) Initial characterization of the human central proteome.. BMC systems biology, 5 (17-17). [PMID:21269460] |
