Recombinant JNK2 Antibody - Primary antibody, specific to JNK2, Rabbit IgG
Synonyms
c Jun kinase 2 antibody; C Jun N terminal kinase 2 antibody; c-Jun N-terminal kinase 2 antibody; JNK 55 antibody; JNK-55 antibody; JNK2 alpha antibody; JNK2 antibody; JNK2 beta antibody; JNK2A antibody; JNK2alpha antibody; JNK2B antibody; JNK2BETA antibod
Specifications & Purity
ExactAb™, Validated, Recombinant, 0.3 mg/mL
Host species
Rabbit
Specificity
JNK2
Immunogen
A synthetic peptide derived from human JNK2 (AA 361-374).
Positive Control
WB: K562, HEK293, C6 and NIH/3T3 cell lysates. IHC: Human colon cancer tissue.
Conjugation
Unconjugated
Grade
ExactAb™, Recombinant, Validated
Product Description
Rabbit anti Human JNK2 Antibody, Recombinant, could be used for WB, IHC and so on. Application: WB: 1/500-1/1000 IHC: 1/50-1/100 Function Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. JNK2 isoforms display different binding patterns: alpha-1 and alpha-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 alpha-2, and JUND binds only weakly to it.
Product Properties
Isotype
Rabbit IgG
SDS-PAGE
150 kDa
Purification Method
Antigen affinity purified
Form
Liquid
Concentration
0.3 mg/mL
Storage Temp
Store at -20°C,Avoid repeated freezing and thawing
Shipped In
Ice chest + Ice pads
Stability And Storage
Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.
Images
Recombinant JNK2 Antibody (Ab111533) - Western Blot All lanes: Recombinant JNK2 Antibody (Ab111533) at 1/2000 dilution Samples: Lysates at 20 µg per lane Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 48 kDa Observed band size: 41, 49 kDa Exposure time: 6.4 s
Recombinant JNK2 Antibody (Ab111533) - IHC Immunohistochemistry analysis of paraffin-embedded Human colon cancer using Recombinant JNK2 Antibody (Ab111533). High-pressure and temperature Sodium Citrate pH 6.0 was used for antigen retrieval.
Associated Targets(Human)
MAPK9TchemMitogen-activated protein kinase 9 (0 Activities)