Recombinant; Rabbit anti Human KAT2B/PCAF Antibody; WB; Unconjugated
| SKU | Size | Availability | Price | Qty |
|---|---|---|---|---|
| Ab111758-10μl | 10μl | In stock | $59.90 | |
| Ab111758-50μl | 50μl | In stock | $179.90 | |
| Ab111758-100μl | 100μl | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $299.90 | |
| Ab111758-1ml | 1ml | Available within 8-12 weeks(?) Production requires sourcing of materials. We appreciate your patience and understanding. | $2,699.90 |
Recombinant; Rabbit anti Human KAT2B/PCAF Antibody; WB; Unconjugated
| Product Name | Recombinant KAT2B/PCAF Antibody - Primary antibody, specific to KAT2B, Rabbit IgG |
|---|---|
| Synonyms | CAF; P/CAF; PCAF; GCN5; GCN5L; GCN5L1; KAT2B; Pcaf; CAF antibody; CREBBP associated factor antibody; GCN5 antibody; GCN5L antibody; GCN5L1 antibody; Histone acetylase PCAF antibody; Histone acetyltransferase KAT2B antibody; Histone acetyltransferase PCAF |
| Specifications & Purity | ExactAb™, Validated, Recombinant, 0.22 mg/mL |
| Host species | Rabbit |
| Specificity | KAT2B |
| Immunogen | A synthetic peptide derived from human KAT2B/PCAF (AA 154-190) |
| Positive Control | WB: HeLa, HEK293, A431, Hep G2 and LNCaP cell lysates. |
| Conjugation | Unconjugated |
| Grade | ExactAb™, Recombinant, Validated |
| Product Description |
Rabbit anti Human KAT2B/PCAF Antibody, Recombinant, could be used for WB and so on. |
| Isotype | Rabbit IgG |
|---|---|
| Light Chain Type | kappa |
| SDS-PAGE | 150 kDa |
| Purification Method | Protein A purified |
| Form | Liquid |
| Concentration | 0.22 mg/mL |
| Storage Temp | Store at -20°C,Avoid repeated freezing and thawing |
| Shipped In | Ice chest + Ice pads |
| Stability And Storage | Store at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle. |
Recombinant KAT2B/PCAF Antibody (Ab111758) - Western Blot
All lanes: Recombinant KAT2B/PCAF Antibody (Ab111758) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/40000 dilution
Predicted band size: 93 kDa
Observed band size: 86 kDa
Exposure time: 9.3 s
| Activity Type | Activity Value -log(M) | Mechanism of Action | Activity Reference | Publications (PubMed IDs) |
|---|
| Application | Dilution info |
|---|---|
| WB | 1/500-1/1000 |
Enter Lot Number to search for COA:
To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section
| Lot Number | Certificate Type | Date | Item |
|---|---|---|---|
 ZJ24F0303368 | Certificate of Analysis | Mar 19, 2024 | Ab111758 |
| ZJ24F0303369 | Certificate of Analysis | Mar 19, 2024 | Ab111758 |
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| 41. Mujtaba, Shiraz S and 7 more authors.. (2002) Structural basis of lysine-acetylated HIV-1 Tat recognition by PCAF bromodomain.. Molecular cell, [PMID:11931765] |
| 42. Brès, Vanessa V and 8 more authors.. (2002) Differential acetylation of Tat coordinates its interaction with the co-activators cyclin T1 and PCAF.. The EMBO journal, (16): [PMID:12486002] |
| 43. Curtis, Anne M AM and 7 more authors.. (2004) Histone acetyltransferase-dependent chromatin remodeling and the vascular clock.. The Journal of biological chemistry, (20): [PMID:14645221] |
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| 47. Shin, Sook S and Janknecht, Ralf R.. (2007) Concerted activation of the Mdm2 promoter by p72 RNA helicase and the coactivators p300 and P/CAF.. Journal of cellular biochemistry, (1): [PMID:17226766] |
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| 49. Gururaj, Anupama E AE, Peng, Shaohua S, Vadlamudi, Ratna K RK and Kumar, Rakesh R.. (2007) Estrogen induces expression of BCAS3, a novel estrogen receptor-alpha coactivator, through proline-, glutamic acid-, and leucine-rich protein-1 (PELP1).. Molecular endocrinology (Baltimore, Md.), [PMID:17505058] |
| 50. Zhu, Ping P and 8 more authors.. (2007) A histone H2A deubiquitinase complex coordinating histone acetylation and H1 dissociation in transcriptional regulation.. Molecular cell, (17): [PMID:17707232] |
| 51. Pickard, Adam A, Wong, Ping-Pui PP and McCance, Dennis J DJ.. (2010) Acetylation of Rb by PCAF is required for nuclear localization and keratinocyte differentiation.. Journal of cell science, (1): [PMID:20940255] |
| 52. Xia, Peng P and 10 more authors.. (2012) EB1 acetylation by P300/CBP-associated factor (PCAF) ensures accurate kinetochore-microtubule interactions in mitosis.. Proceedings of the National Academy of Sciences of the United States of America, (9): [PMID:23001180] |
| 53. Lin, Ruiting R and 7 more authors.. (2013) Acetylation stabilizes ATP-citrate lyase to promote lipid biosynthesis and tumor growth.. Molecular cell, (22): [PMID:23932781] |
| 54. Gong, Fade F and 11 more authors.. (2015) Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.. Genes & development, (15): [PMID:25593309] |
| 55. Chen, Sifan S and 6 more authors.. (2016) SIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing.. Nature communications, (12): [PMID:26867678] |
| 56. Fournier, Marjorie M and 11 more authors.. (2016) KAT2A/KAT2B-targeted acetylome reveals a role for PLK4 acetylation in preventing centrosome amplification.. Nature communications, (31): [PMID:27796307] |
| 57. Rainger, Joe J and 15 more authors.. (2017) A recurrent de novo mutation in ACTG1 causes isolated ocular coloboma.. Human mutation, [PMID:28493397] |
| 58. Ghosh, Tushar K TK and 7 more authors.. (2018) Acetylation of TBX5 by KAT2B and KAT2A regulates heart and limb development.. Journal of molecular and cellular cardiology, [PMID:29174768] |
