Recombinant KAT9/Elp3 Antibody - Primary antibody, specific to KAT9/Elp3, Rabbit IgG

    Application:
  • WB
Features and benefits
  • Host species: Rabbit
  • Species reactivity(Reacts with): Human,Mouse,Rat
  • Isotype: Rabbit IgG
  • Conjugation: Unconjugated
Item Number
Ab111794
Grouped product items
SKUSizeAvailabilityPrice Qty
Ab111794-10μl
10μl
In stock
$66.90
Ab111794-50μl
50μl
In stock
$199.90
Ab111794-100μl
100μl
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$299.90
Ab111794-1ml
1ml
Available within 8-12 weeks(?)
Production requires sourcing of materials. We appreciate your patience and understanding.
$2,799.90

Recombinant; Rabbit anti Human KAT9/Elp3 Antibody; WB; Unconjugated

Basic Description

Product NameRecombinant KAT9/Elp3 Antibody - Primary antibody, specific to KAT9/Elp3, Rabbit IgG
SynonymsInterleukin 1 Receptor-like 2 | IL-1 R6 | IL-1 Rrp2 | IL1RL2 | IL-1RL2 | IL1Rrp2 | IL-1Rrp2 | IL1RRP2IL1R-rp2Interleukin-1 receptor-related protein 2 | interleukin-1 receptor-like 2 | IL-36R | IL1R-rp2 | 2.3.1.- | hELP3 | Protein lysine acetyltransferase
Specifications & PurityExactAb™, Validated, Recombinant, 1.0 mg/mL
Host speciesRabbit
SpecificityKAT9/Elp3
ImmunogenA synthetic peptide derived from human KAT9/Elp3 (AA 1-547)
Positive ControlWB: HeLa, K562, Hep G2, Jurkat, MCF7 and HEK293 cell lysates.
ConjugationUnconjugated
GradeExactAb™, Recombinant, Validated
Product Description

Rabbit anti Human KAT9/Elp3 Antibody, Recombinant, could be used for WB and so on.
Application:
WB: 1/500-1/1000
Protein Function:
Catalytic histone acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. May also have a methyltransferase activity.

Product Properties

IsotypeRabbit IgG
Light Chain Typekappa
SDS-PAGE150 kDa
Purification MethodProtein A purified
FormLiquid
Concentration1.0 mg/mL
Storage TempStore at -20°C,Avoid repeated freezing and thawing
Shipped InIce chest + Ice pads
Stability And StorageStore at 4°C short term (1-2 weeks). Store at -20°C long term (24 months). Upon delivery aliquot. Avoid freeze/thaw cycle.

Images

Recombinant KAT9/Elp3 Antibody (Ab111794) - Western Blot
All lanes: Recombinant KAT9/Elp3 Antibody (Ab111794) at 1/1000 dilution
Samples: Lysates at 20 µg per lane
Secondary: Goat Anti-Rabbit IgG H&L (HRP) (Ab170144) at 1/20000 dilution
Predicted band size: 62 kDa
Observed band size: 49, 61 kDa
Exposure time: 14.6 s

Associated Targets(Human)

ELP3 Tbio Elongator complex protein 3 (0 Activities)
Activity TypeActivity Value -log(M)Mechanism of ActionActivity ReferencePublications (PubMed IDs)

Application

ApplicationDilution info
WB1/500-1/1000

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1/500-1/1000

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

Find and download the COA for your product by matching the lot number on the packaging.

2 results found

Lot NumberCertificate TypeDateItem
ZJ24F0505531Certificate of AnalysisMay 14, 2024 Ab111794
ZJ24F0505530Certificate of AnalysisMay 14, 2024 Ab111794

Related Documents

References

1. Hawkes, Nicola A NA and 11 more authors..  (2002)  Purification and characterization of the human elongator complex..  The Journal of biological chemistry,    (25):   [PMID:11714725]
2. Kim, Jae-Hyun JH, Lane, William S WS and Reinberg, Danny D..  (2002)  Human Elongator facilitates RNA polymerase II transcription through chromatin..  Proceedings of the National Academy of Sciences of the United States of America,    (5):   [PMID:11818576]
3. Rush, John J and 9 more authors..  (2005)  Immunoaffinity profiling of tyrosine phosphorylation in cancer cells..  Nature biotechnology,      [PMID:15592455]
4. Nusbaum, Chad C and 75 more authors..  (2006)  DNA sequence and analysis of human chromosome 8..  Nature,    (19):   [PMID:16421571]
5. Close, Pierre P and 11 more authors..  (2006)  Transcription impairment and cell migration defects in elongator-depleted cells: implication for familial dysautonomia..  Molecular cell,    (19):   [PMID:16713582]
6. Bechtel, Stephanie S and 18 more authors..  (2007)  The full-ORF clone resource of the German cDNA Consortium..  BMC genomics,    (31):   [PMID:17974005]
7. Simpson, Claire L CL and 29 more authors..  (2009)  Variants of the elongator protein 3 (ELP3) gene are associated with motor neuron degeneration..  Human molecular genetics,    (1):   [PMID:18996918]
8. Creppe, Catherine C and 16 more authors..  (2009)  Elongator controls the migration and differentiation of cortical neurons through acetylation of alpha-tubulin..  Cell,    (6):   [PMID:19185337]
9. Mayya, Viveka V and 7 more authors..  (2009)  Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions..  Science signaling,    (18):   [PMID:19690332]
10. Ahmad, Yasmeen; Boisvert, Francois-Michel; Lundberg, Emma; Uhlen, Mathias and Lamond, Angus I..  (2012)  Systematic analysis of protein pools, isoforms, and modifications affecting turnover and subcellular localization..  Molecular & cellular proteomics : MCP,      [PMID:22002106]
11. Close, Pierre P and 11 more authors..  (2012)  DERP6 (ELP5) and C3ORF75 (ELP6) regulate tumorigenicity and migration of melanoma cells as subunits of Elongator..  The Journal of biological chemistry,    (21):   [PMID:22854966]
12. Guo, Ailan and 15 more authors..  (2014)  Immunoaffinity enrichment and mass spectrometry analysis of protein methylation..  Molecular & cellular proteomics : MCP,      [PMID:24129315]
13. Dong, Chunming C and 9 more authors..  (2015)  The Elp2 subunit is essential for elongator complex assembly and functional regulation..  Structure (London, England : 1993),    (2):   [PMID:25960406]
14. Dalwadi, Udit U and Yip, Calvin K CK..  (2018)  Structural insights into the function of Elongator..  Cellular and molecular life sciences : CMLS,      [PMID:29332244]
15. Bento-Abreu, Andre A and 22 more authors..  (2018)  Elongator subunit 3 (ELP3) modifies ALS through tRNA modification..  Human molecular genetics,    (1):   [PMID:29415125]
16. Thomas R Burkard,Melanie Planyavsky,Ines Kaupe,Florian P Breitwieser,Tilmann Bürckstümmer,Keiryn L Bennett,Giulio Superti-Furga,Jacques Colinge.  (2011-01-29)  Initial characterization of the human central proteome..  BMC systems biology,  (17-17).  [PMID:21269460]

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